Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Guowen Jia"'
Autor:
Zhou Tong, Jianyu Tong, Wenwen Lei, Yufeng Xie, Yingzi Cui, Guowen Jia, Shihua Li, Zezhong Zhang, Zhimin Cheng, Xiao Xing, Haiyun Ma, Lan Deng, Rong Zhang, Xin Zhao, Kefang Liu, Qihui Wang, Jianxun Qi, Haomin Huang, Rui Song, Zhaoming Su, Guizhen Wu, Jing Lou, George Fu Gao
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114338- (2024)
Summary: The game between therapeutic monoclonal antibodies (mAbs) and continuously emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has favored the virus, as most therapeutic mAbs have been evaded. Addressing this chall
Externí odkaz:
https://doaj.org/article/a73e673f4b47432cb7e3e0b7cbab3ca8
Autor:
Yan Wang, Chong Zhang, Yongbo Luo, Xiaobin Ling, Bingnan Luo, Guowen Jia, Dan Su, Haohao Dong, Zhaoming Su
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Respiratory syncytial virus (RSV) is a nonsegmented, negative strand RNA virus that has caused severe lower respiratory tract infections of high mortality rates in infants and the elderly, yet no effective vaccine or antiviral therapy is ava
Externí odkaz:
https://doaj.org/article/4e9714bad1894559ad41ee35a8a02f35
Autor:
Yan Wang, Xiaobin Ling, Chong Zhang, Jian Zou, Bingnan Luo, Yongbo Luo, Xinyu Jia, Guowen Jia, Minghua Zhang, Junchao Hu, Ting Liu, Yuanfeiyi Wang, Kefeng Lu, Dan Li, Jinbiao Ma, Cong Liu, Zhaoming Su
Publikováno v:
Molecular Biomedicine, Vol 4, Iss 1, Pp 1-14 (2023)
Abstract SARS-CoV-2 and its variants, with the Omicron subvariant XBB currently prevailing the global infections, continue to pose threats on public health worldwide. This non-segmented positive-stranded RNA virus encodes the multi-functional nucleoc
Externí odkaz:
https://doaj.org/article/0e7267bf39754639bc66cdc375359333
Autor:
Cai He, Jingyun Yang, Weiqi Hong, Zimin Chen, Dandan Peng, Hong Lei, Aqu Alu, Xuemei He, Zhenfei Bi, Xiaohua Jiang, Guowen Jia, Yun Yang, Yanan Zhou, Wenhai Yu, Cong Tang, Qing Huang, Mengli Yang, Bai Li, Jingmei Li, Junbin Wang, Haiying Que, Li Chen, Wenyan Ren, Dandan Wan, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Zhaoming Su, Yuquan Wei, Xiaobo Cen, Yoshimasa Tanaka, Xiangrong Song, Shuaiyao Lu, Xiaozhong Peng, Guangwen Lu, Xiawei Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The SARS-CoV-2 Omicron variant has quickly become the predominant circulating variant, due to the high transmissibility and immune escape. Here, the authors develop a trimeric protein vaccine candidate and show a sustained humoral immune response, an
Externí odkaz:
https://doaj.org/article/6931d87e1b9f415882b4ac5ac20fee24
Autor:
Yidan Xu, Guowen Jia, Tingting Li, Zixuan Zhou, Yitian Luo, Yulin Chao, Juan Bao, Zhaoming Su, Qianhui Qu, Dianfan Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
GPI-T catalyzes the committed step in GPI anchor protein biogenesis. Here, Xu et al. report the cryo-EM structure of the human GPI-T, revealing critical elements within an elongated, shared active site which is topologically arranged for substrate sp
Externí odkaz:
https://doaj.org/article/adcaed8c934d4f11b08b9d290288a8e0
Autor:
Bingnan Luo, Chong Zhang, Xiaobin Ling, Sunandan Mukherjee, Guowen Jia, Jiahao Xie, Xinyu Jia, Liu Liu, Eugene F. Baulin, Yongbo Luo, Longxing Jiang, Haohao Dong, Xiawei Wei, Janusz M. Bujnicki, Zhaoming Su
Publikováno v:
Nature Catalysis. 6:298-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6d0169654a18817ff1ada29f7c13b7
https://doi.org/10.1038/s41929-023-00934-3
https://doi.org/10.1038/s41929-023-00934-3
Autor:
Xinyu Jia, Zhiling Pan, Yang Yuan, Bingnan Luo, Yongbo Luo, Sunandan Mukherjee, Guowen Jia, Liu Liu, Xiaobin Ling, Xiting Yang, Zhichao Miao, Xiawei Wei, Janusz M. Bujnicki, Kelei Zhao, Zhaoming Su
Publikováno v:
Cell Research. 33:328-330
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::775d6d0905b94222ef69dc41616291d1
https://doi.org/10.1038/s41422-023-00786-3
https://doi.org/10.1038/s41422-023-00786-3
Cryo-EM structure of the Mon1–Ccz1–RMC1 complex reveals molecular basis of metazoan RAB7A activation
Autor:
Xin Yong, Guowen Jia, Zhe Liu, Chunzhuang Zhou, Jiamin Yi, Yingying Tang, Li Chen, Lu Chen, Yuan Wang, Qingxiang Sun, Daniel D. Billadeau, Zhaoming Su, Da Jia
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Understanding of the evolution of metazoans from their unicellular ancestors is a fundamental question in biology. In contrast to fungi which utilize the Mon1–Ccz1 dimeric complex to activate the small GTPase RAB7A, metazoans rely on the Mon1–Ccz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::273e35b616770f3fb66505b81bc9e814
https://doi.org/10.1073/pnas.2301725120
https://doi.org/10.1073/pnas.2301725120
Autor:
Xinyu Jia, Zhiling Pan, Yang Yuan, Bingnan Luo, Yongbo Luo, Sunandan Mukherjee, Guowen Jia, Liu Liu, Xiaobin Ling, Xiting Yang, Zhichao Miao, Xiawei Wei, Janusz M. Bujnicki, Kelei Zhao, Zhaoming Su
Pseudomonas aeruginosais an opportunistic human pathogen that poses threats to hospitalized immunocompromised patients1. A non-coding small RNA (sRNA) from the repressor of secondary metabolites (Rsm) system, RsmZ, sequesters the global repressor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e132f50a76dbb3a66322bc5d0625a4e1
https://doi.org/10.1101/2022.11.16.516715
https://doi.org/10.1101/2022.11.16.516715
Autor:
Weiqi Hong, Jingyun Yang, Jun Zou, Zhenfei Bi, Cai He, Hong Lei, Xuemei He, Xue Li, Aqu Alu, Wenyan Ren, Zeng Wang, Xiaohua Jiang, Kunhong Zhong, Guowen Jia, Yun Yang, Wenhai Yu, Qing Huang, Mengli Yang, Yanan Zhou, Yuan Zhao, Dexuan Kuang, Junbin Wang, Haixuan Wang, Siyuan Chen, Min Luo, Ziqi Zhang, Tianqi Lu, Li Chen, Haiying Que, Zhiyao He, Qiu Sun, Wei Wang, Guobo Shen, Guangwen Lu, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Jiong Li, Xiangrong Song, Lunzhi Dai, Chong Chen, Jia Geng, Maling Gou, Lu Chen, Haohao Dong, Yong Peng, Canhua Huang, Zhiyong Qian, Wei Cheng, Changfa Fan, Yuquan Wei, Zhaoming Su, Aiping Tong, Shuaiyao Lu, Xiaozhong Peng, Xiawei Wei
Publikováno v:
Cellularmolecular immunology. 19(5)
Neutrophil extracellular traps (NETs) can capture and kill viruses, such as influenza viruses, human immunodeficiency virus (HIV), and respiratory syncytial virus (RSV), thus contributing to host defense. Contrary to our expectation, we show here tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46af4ac9abe54bc4bb89b301bce140a
https://pubmed.ncbi.nlm.nih.gov/35273357
https://pubmed.ncbi.nlm.nih.gov/35273357