Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Guotao Tang"'
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13722- (2023)
Zinc depletion is associated with alcohol-associated liver injury. We tested the hypothesis that increasing zinc availability along with alcohol consumption prevents alcohol-associated liver injury. Zinc-glutathione (ZnGSH) was synthesized and direct
Externí odkaz:
https://doaj.org/article/e75b71bde8af440ab1b839d86855a206
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 47, Iss 1, Pp 2800-2809 (2019)
Triple-negative breast cancer (TNBC) is a distinct subtype of breast cancer characterized by high recurrence rates and poor prognosis compared to other breast cancers. MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of vario
Externí odkaz:
https://doaj.org/article/2b41381645af452a927c638571d37161
Autor:
Xiangping Deng, Zhongli Li, Runde Xiong, Juan Liu, Renbo Liu, Junmei Peng, Yanming Chen, Xiaoyong Lei, Xuan Cao, Xing Zheng, Zhizhong Xie, Guotao Tang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 1659-1669 (2019)
In this study, we investigated the anticancer effects of FS-7, a flavonoid salicylate derivative, in human gastric carcinoma MGC-803 cell line and studied its preliminary anticancer effects. FS-7 displayed greater in vitro cytotoxicity against MGC-80
Externí odkaz:
https://doaj.org/article/417eee55abbf4251b8235df85b99a2d6
Publikováno v:
Intelligent Pharmacy; Apr2024, Vol. 2 Issue 2, p161-172, 12p
Autor:
Xueyan Sun, Yin Zhao, Jingduo Zhao, Zhizhong Xie, Xiaoyong Lei, Xingyun Liu, Yong Li, Sheng Huang, Zhe Wang, Guotao Tang
Publikováno v:
Drug Development Research. 84:448-464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46c946d835ffdbfb099cec57fc2e8700
https://doi.org/10.1002/ddr.22035
https://doi.org/10.1002/ddr.22035
Autor:
Kaiyue Wu, Xiaoyu Peng, Miaojia Chen, Yang Li, Guotao Tang, Junmei Peng, Yuanyuan Peng, Xuan Cao
Publikováno v:
Chemical Biology & Drug Design. 99:736-757
With the development of exploration for disease-related proteins or receptors, more and more novel structural lead compounds are required to designed and synthesized. The benzimidazole is an effective structural unit in which the benzene ring is fuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cf311b020d1efd1cf10783721e1695
https://doi.org/10.1111/cbdd.14022
https://doi.org/10.1111/cbdd.14022
Autor:
Xiangping Deng, Yang Zou, Renbo Liu, Yijiao Peng, Chenglin Ouyang, Junmei Peng, Xiaoyong Lei, Zhizhong Xie, Chong Li, Guotao Tang
Publikováno v:
Polycyclic Aromatic Compounds. 43:980-999
A series of flavonoid derivatives bearing trimethoxyphenyl and benzimidazole were designed, synthesized and evaluated as potential anti-tumor agents. Compound 5g showed remarkable inhibitory activity against SGC-7901, HGC-27 and MCF-7 (IC50 values of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ac94635ecce5d253a4a13ee141069b
https://doi.org/10.1080/10406638.2021.2021251
https://doi.org/10.1080/10406638.2021.2021251
Autor:
Zixuan Zhong, Jianglin Shi, Zhe Fu, Guotao Tang, Haoting Wu, Guolu Yin, Tao Liu, Nan Guo, Tao Zhu
Publikováno v:
Thirteenth International Conference on Information Optics and Photonics (CIOP 2022).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80b6d097ad036c17cfa1d569696e9a4
https://doi.org/10.1117/12.2654907
https://doi.org/10.1117/12.2654907
Autor:
Ying Yin, Yan Tan, Xueni Wei, Xiaoshun Li, Hongfei Chen, Zehua Yang, Guotao Tang, Xu Yao, Pengbing Mi, Xing Zheng
Publikováno v:
Chemistry & Biodiversity. 19
Curcumin is a potential plant-derived drug for the treatment of breast cancer. Poor solubility and bioavailability are the main factors that limit its clinical application. Various structural modification strategies have been developed to improve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49353484bd8fdd50a3135af3b0e56d8
https://doi.org/10.1002/cbdv.202200485
https://doi.org/10.1002/cbdv.202200485
Autor:
Kaiyue Wu, Honglin Huang, Junmei Peng, Miaojia Chen, Yunfan Liu, Lizhi Jiang, Guotao Tang, Yang Li, Xuan Cao
Publikováno v:
Drug Development Research. 83:55-63
Although 1H-benzo[d]imidazole-4-carboxamide derivatives have been explored for a long time, the structure-activity relationship of the substituents in the hydrophobic pocket (AD binding sites) has not thoroughly discovered. Here in, a series of 2-(4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54df80087613fd125d912160e5f6339c
https://doi.org/10.1002/ddr.21843
https://doi.org/10.1002/ddr.21843