Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Guoshuai, Yang"'
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract Background Ischemic stroke (IS) is known for its high morbidity, disability and mortality rates, and studies designed to explore its pathophysiological mechanisms and identify novel therapeutic strategies are urgently needed. We aimed to pro
Externí odkaz:
https://doaj.org/article/9f8ba6432cc74352a21f98c64bb4b611
Autor:
Kaibin Huang, Xiaolin Zhao, Yunxiao Zhao, Guoshuai Yang, Saijun Zhou, Zhi Yang, Wenguo Huang, Guohu Weng, Pingyan Chen, Chongyang Duan, Zhenzhou Lin, Shengnan Wang, Xiangmin Liu, Yunqiang Huang, Jiangshan Zhang, Xu Zhang, Hao Li, Songsheng Ye, Yong Gu, Minzhen Zhu, Weiying Chen, Weiwei Quan, Na Liu, Quanfeng Chen, Yuan Chang, Jinzhao He, Zhong Ji, Yongming Wu, Suyue Pan
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102305- (2023)
Summary: Background: Glibenclamide alleviates brain edema and improves neurological outcomes in experimental models of stroke. We aimed to assess whether glibenclamide improves functional outcomes in patients with acute ischemic stroke treated with r
Externí odkaz:
https://doaj.org/article/08b97e63e0a14ebabf16ff6e7d260664
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 95, Iss suppl 1 (2023)
Abstract Sleep deprivation (SD) can lead to cognitive impairment caused by neuroinflammation. MiR-181c-5p/HMGB1 axis plays a part in anti-inflammation effects. However, the mechanism that miR-181c-5p facilitates learning and memory in SD mice remains
Externí odkaz:
https://doaj.org/article/e23b0db8519746a58a28b86df48844b7
Publikováno v:
Brain and Behavior, Vol 13, Iss 1, Pp n/a-n/a (2023)
Abstract Purpose To investigate the mechanism underlying the regulatory effect of melatonin on chronic sleep deprivation‐related cognitive impairment. Methods Chronic sleep deprivation (CSD) model was established using the MMPM method. After the mo
Externí odkaz:
https://doaj.org/article/3678fe69d1434ff6aa2d8897a9a71e55
Autor:
Kaibin Huang, Zhong Ji, Yongming Wu, Yunqiang Huang, Guangning Li, Saijun Zhou, Zhi Yang, Wenguo Huang, Guoshuai Yang, Guohu Weng, Pingyan Chen, Suyue Pan
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Thrombolysis with recombinant tissue plasminogen activator (rtPA) improves outcome for patients with acute ischemic stroke (AIS), but many of them still have substantial disability. Glibenclamide (US adopted name, glyburide), a lo
Externí odkaz:
https://doaj.org/article/ccd876cd5e254269ae584d4133abbc16
Publikováno v:
Neural Plasticity, Vol 2022 (2022)
Small extracellular vesicles (sEVs) secreted by mesenchymal stem cells (MSCs) have shown great therapeutic potential in cerebral ischemia-reperfusion injury (CIRI). In this study, we firstly performed a systematic review to evaluate the efficacy of M
Externí odkaz:
https://doaj.org/article/382d364aff244a32ad85367684db28d3
Publikováno v:
Acta Neurobiologiae Experimentalis; 2024, Vol. 84 Issue 2, p203-217, 15p
This report aimed to explore whether miR-188-5p regulated the pathological regulatory network of cerebral ischemia/reperfusion (I/R) injury. We simulated the cerebral I/R injury model with MACO/R and OGD/R treatments. Neuronal viability and apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59c47638d7e1f798a14add55be3fa17f
https://doi.org/10.21203/rs.3.rs-2385373/v1
https://doi.org/10.21203/rs.3.rs-2385373/v1
Publikováno v:
Brain and behaviorREFERENCES.
To investigate the mechanism underlying the regulatory effect of melatonin on chronic sleep deprivation-related cognitive impairment.Chronic sleep deprivation (CSD) model was established using the MMPM method. After the model was established, melaton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a260fe9eecf03c3712f9f650d263ea5
https://pubmed.ncbi.nlm.nih.gov/36563187
https://pubmed.ncbi.nlm.nih.gov/36563187