Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Guorui Dou"'
Autor:
Yali Niu, Yixuan Xi, Yutong Jing, Ziyi Zhou, Xiaojia Sun, Guoheng Zhang, Tianhao Yuan, Tianfang Chang, Guorui Dou
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1979 (2023)
The outer blood–retina barrier (oBRB), comprises tightly connected retinal pigment epithelium (RPE) cells, Bruch’s membrane, and choroid blood vessels, and is essential for retinal health and normal visual function. Disruption of the RPE barrier
Externí odkaz:
https://doaj.org/article/0cb7cd40cb59425687c07d2aa476c4e5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15516 (2023)
Galectin-3 is the most studied member of the Galectin family, with a large range of mediation in biological activities such as cell growth, proliferation, apoptosis, differentiation, cell adhesion, and tissue repair, as well as in pathological proces
Externí odkaz:
https://doaj.org/article/85f14c891d7c41ec86fa0df127b6f9ac
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 215 (2023)
Oxidative stress is an imbalance between the increased production of reactive species and reduced antioxidant activity, which can cause a variety of disturbances including ocular diseases. Lycium barbarum polysaccharides (LBPs) are complex polysaccha
Externí odkaz:
https://doaj.org/article/3ed1a657dd8149b18488d54231de944e
Autor:
Ziyi Zhou, Yutong Jing, Yali Niu, Tianfang Chang, Jiaxing Sun, Changmei Guo, Yusheng Wang, Guorui Dou
Publikováno v:
Life, Vol 12, Iss 10, p 1676 (2022)
Microglia is the resident immune cell in the retina, playing the role of immune surveillance in a traditional concept. With the heated focus on the mechanisms of microglia in pathological conditions, more and more functions of microglia have been dis
Externí odkaz:
https://doaj.org/article/7655f013210c4624be28461803a595c7
Autor:
Wenqin Xu, Ying Wu, Zhicha Hu, Lijuan Sun, Guorui Dou, Zifeng Zhang, Haiyang Wang, Changmei Guo, Yusheng Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 778-790 (2019)
The role of microglia in the pathophysiology of ischemic retinal diseases has been studied extensively. Exosomes from microglial cells exert protective effects during several nervous system diseases, but their roles in hypoxia-induced retinopathy rem
Externí odkaz:
https://doaj.org/article/79fd1d35f8c94263b626c8a1b9293f60
Autor:
Wenqin Xu, Jie Yin, Lijuan Sun, Zhicha Hu, Guorui Dou, Zifeng Zhang, Haiyan Wang, Changmei Guo, Yusheng Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The role of microglia in the pathophysiology of ischemic retinal diseases has been extensively studied. Retinal microglial activation may be correlated with retinal neovascularization in oxygen-induced retinopathy (OIR), an animal model that
Externí odkaz:
https://doaj.org/article/92716593bbc5490fb7fd63d0262e65a3
Autor:
Qian Bai, Xin Wang, Hongxiang Yan, Lishi Wen, Ziyi Zhou, Yating Ye, Yutong Jing, Yali Niu, Liang Wang, Zifeng Zhang, Jingbo Su, Tianfang Chang, Guorui Dou, Yusheng Wang, Jiaxing Sun
Publikováno v:
Journal of Personalized Medicine; Volume 13; Issue 1; Pages: 146
Pathological retinal neovascularization (RNV) is the main character of ischemic ocular diseases, which causes severe visual impairments. Though retinal microglia are well acknowledged to play important roles in both physiological and pathological ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7712e1e4058b12ff0edf0caebf33c8a1
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 19; Pages: 12173
As the global trend of diabetes intensifies, the burden of vision-threatening retinopathy, particularly diabetic retinopathy (DR), is increasing. There is an urgent need to seek strategies for early prevention and control of DR. This study attempted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc98eccab2214d78b4b527bfe4bd1b8
https://pubmed.ncbi.nlm.nih.gov/36231475
https://pubmed.ncbi.nlm.nih.gov/36231475
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98275 (2014)
Age-related macular degeneration (AMD) is a leading cause of blindness in the developed world. The retinal pigment epithelium (RPE) is a critical site of pathology in AMD and αB crystallin expression is increased in RPE and associated drusen in AMD.
Externí odkaz:
https://doaj.org/article/62f3fe593fbc47c9ab034115b3320fb7
Publikováno v:
International journal of biological sciences. 17(7)
Nonalcoholic fatty liver disease (NAFLD), or, more accurately, metabolic associated fatty liver disease, accounts for a large proportion of chronic liver disorders worldwide and is closely associated with other conditions such as cardiovascular disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c071d43092f043124e4f6487dbd6f78
https://pubmed.ncbi.nlm.nih.gov/33994867
https://pubmed.ncbi.nlm.nih.gov/33994867