Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Guoqiang, Lin"'
Autor:
Feng Wang, Tiancheng Ma, Donglan Liu, Yixin Cen, Shidong Deng, Lu Zhang, Guoqiang Lin, Dingding Gao, Jincun Zhao, Jiajia Dong, Ping Tian
Publikováno v:
Acta Materia Medica, Vol 3, Iss 3, Pp 328-344 (2024)
The 3C-like protease (3CLpro) is a crucial target in anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) drug design. Herein, we performed high-throughput synthesis of catechol derivatives from the bioactive catechol-terminal alkyne sca
Externí odkaz:
https://doaj.org/article/c1b1dac4620848068740f5f672bacf6d
Autor:
Ziyi Hao, Yingying Fei, Juan Chen, Sailan Huang, Li Wang, Youhuan Yu, Meiru Bian, Yejun Si, Xingxia Zhang, Xiaotian Yang, Bing Zhang, Yan Wan, Guoqiang Lin, Yanming Zhang
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Objectives: Relapsed/refractory acute B-cell lymphoblastic leukemia (R/R B-ALL) often responds poorly to induction chemotherapy. However, recent research has shown a novel and effective drug treatment for R/R B-ALL.Methods: A total of eight patients
Externí odkaz:
https://doaj.org/article/8b52a6c0ae8f44cdb0db680bdba9c427
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39706- (2024)
Aims: Behavioral risks including tobacco use, alcohol use, low physical activity and dietary risks had been proven to contribute to the pathological process in cardiovascular diseases (CVD). Herein the lethal effects attributable to behavioral risks
Externí odkaz:
https://doaj.org/article/2b1030a9d5894ce981b1c56d6b407348
Autor:
Guoqiang, Lin
Variable selection is a classic problem in statistics. In this paper, we consider a Bayes variable selection problem based on spike-and-slab prior with mixed normal distribution proposed by Ro\v{c}kov\'a and George (2014). Motivated by Ormerod and Yo
Externí odkaz:
http://arxiv.org/abs/2211.11383
Autor:
Yi Miao, Jing Zhang, Xuzhang Lu, Meng Wu, Bingzong Li, Liang Yu, Miao Sun, Yun Zhuang, Yuqing Miao, Haiwen Ni, Xiaoyan Xie, Jingyan Xu, Yunping Zhang, Min Zhao, Min Xu, Wanchuan Zhuang, Weiying Gu, Guoqiang Lin, Haiying Hua, Jianfeng Zhu, Maozhong Xu, Tao Jia, Ping Liu, Lijia Zhai, Tongtong Zhang, Qiurong Shan, Qiudan Shen, Jun Qian, Chunling Wang, Jianyong Li, Wenyu Shi
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Background Lymphoma is the most common secondary cause of hemophagocytic lymphohistiocytosis (HLH) in adults. Lymphoma‐associated HLH (LA‐HLH) in the elderly population is not rare, however, little has been reported regarding clinicopath
Externí odkaz:
https://doaj.org/article/ac98d6cbd8ca4940947d703242305288
Publikováno v:
Journal of Materials Research and Technology, Vol 29, Iss , Pp 4151-4162 (2024)
As a kind of protective material, Diamond-Like Carbon (DLC) film can effectively improve the mechanical and tribological properties of the substrate surface. In DLC family, tetrahedral amorphous carbon (ta-C) with ultra-high hardness and excellent p
Externí odkaz:
https://doaj.org/article/65e905578e224eba9965077b24d84f6a
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30952- (2024)
Ischemia-reperfusion injury (IRI) encompasses the damage resulting from the restoration of blood supply following tissue ischemia. This phenomenon commonly occurs in clinical scenarios such as hemorrhagic shock, severe trauma, organ transplantation,
Externí odkaz:
https://doaj.org/article/586caacaaa3148788dba49e19b06d318
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background and aims The increasing prevalence of metabolic and cardiovascular diseases poses a significant challenge to global healthcare systems. Regular physical activity (PA) is recognized for its positive impact on cardiovascular risk fa
Externí odkaz:
https://doaj.org/article/58f473fbe80b498b9a121f1edbb75f92
Autor:
Junchao Tan, Guoqiang Lin, Rui Zhang, Yuting Wen, Chunying Luo, Ran Wang, Feiyun Wang, Shoujiao Peng, Jiange Zhang
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1179 (2024)
Bufotalin (BT), a major active constituent of Chansu, has been found to possess multiple pharmacological activities. Although previous studies have shown that BT could inhibit the growth of glioblastoma (GBM), the safety of BT in vivo and the potenti
Externí odkaz:
https://doaj.org/article/e7f7eb1e9d30406d9853e60041e7d822
Publikováno v:
Buildings, Vol 14, Iss 1, p 173 (2024)
Existing model tests for reinforcing loess slopes with stabilizing piles are often challenged by simulation inaccuracies in lateral loading modes and scaling. Addressing these concerns, this study conducts model tests and numerical simulations to scr
Externí odkaz:
https://doaj.org/article/ed4fc839cd5941b9a9308530c9609339