Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Guoping Fan"'
Autor:
Qian Liu, Jun Liu, Minmei Guo, Tzu-Cheng Sung, Ting Wang, Tao Yu, Zeyu Tian, Guoping Fan, Wencan Wu, Akon Higuchi
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Retinal degeneration (RD) is a group of disorders on irreversible vision loss. Multiple types of stem cells were used in clinical trials for RD treatment. However, it remains unknown what kinds of stem cells are most effective for
Externí odkaz:
https://doaj.org/article/3a9b2a2f8eca4935a435e775f297ee59
Autor:
Li Ma, Feng Wang, Yangping Li, Jing Wang, Qing Chang, Yuanning Du, Jotham Sadan, Zhen Zhao, Guoping Fan, Bing Yao, Jian-Fu Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract How early life experience is translated into storable epigenetic information leading to behavioral changes remains poorly understood. Here we found that Zika virus (ZIKV) induced-maternal immune activation (MIA) imparts offspring with anxiet
Externí odkaz:
https://doaj.org/article/95a0f8e578504aada7b751d4d80cfcf6
Autor:
Tengfei Wang, Shuxiang Shi, Yuanyuan Shi, Peipei Jiang, Ganlu Hu, Qinying Ye, Zhan Shi, Kexin Yu, Chenguang Wang, Guoping Fan, Suwen Zhao, Hanhui Ma, Alex C. Y. Chang, Zhi Li, Qian Bian, Chao-Po Lin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Chemicals or drugs can accumulate within biomolecular condensates formed through phase separation in cells. Here, we use super-resolution imaging to search for chemicals that induce phase transition within chromatin at the microscale. This m
Externí odkaz:
https://doaj.org/article/3515f8cbf8e5467ab24066c5ddff6073
Autor:
Doudou Xu, Boyang Wan, Kai Qiu, Yubo Wang, Xin Zhang, Ning Jiao, Enfa Yan, Jiangwei Wu, Run Yu, Shuai Gao, Min Du, Chousheng Liu, Mingzhou Li, Guoping Fan, Jingdong Yin
Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract Skeletal muscle comprises a large, heterogeneous assortment of cell populations that interact to maintain muscle homeostasis, but little is known about the mechanism that controls myogenic development in response to artificial selection. Dif
Externí odkaz:
https://doaj.org/article/63e35870064c4a539387a3334e52235e
Autor:
Xianmin Zhu, Yuehua Gao, Yimiao Feng, Jie Zheng, Yixiao Dong, Peng Zhang, Yuming Zhu, Guoping Fan
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 3, Pp n/a-n/a (2023)
Abstract Small cell lung cancer (SCLC) originates from pulmonary neuroendocrine cells and accounts for approximately 15% of lung cancer incidents. Patients with SCLC have a very low survival rate due to fast progression and early metastasis. Despite
Externí odkaz:
https://doaj.org/article/781961d2f08440279ce913c3715b6faa
Autor:
Chenglei Tian, Jing Wang, Xiaoying Ye, Jiyu Chen, Rongyan Zheng, Hanwen Yu, Jie Li, Guoxing Yin, Linlin Liu, Nannan Zhao, Guofeng Feng, Zhengmao Zhu, Jichang Wang, Guoping Fan, Lin Liu
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112645- (2023)
Summary: Various culture conditions by small molecules have been explored to extend pluripotency of stem cells, but their impacts on cell fate in vivo remain elusive. We systematically compared the effects of various culture conditions on the pluripo
Externí odkaz:
https://doaj.org/article/41f7efbba1fc497caeccbcd5bf97cff6
Autor:
Xili Ding, Qin An, Weikang Zhao, Yang Song, Xiaokai Tang, Jing Wang, Chih-Chiang Chang, Gexin Zhao, Tzung Hsiai, Guoping Fan, Yubo Fan, Song Li
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
Vascular smooth muscle cells (SMCs) are heterogeneous, and their differential responses to vascular injury are not well understood. To address this question, we performed single-cell analysis of vascular cells to a ligation injury in mouse carotid ar
Externí odkaz:
https://doaj.org/article/db7d9c388ec54b0c9d6b46aac87a2503
Autor:
Youjin Hu, Jiawei Zhong, Yuhua Xiao, Zheng Xing, Katherine Sheu, Shuxin Fan, Qin An, Yuanhui Qiu, Yingfeng Zheng, Xialin Liu, Guoping Fan, Yizhi Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Most single-cell RNA sequencing methods have limited ability to profile the transcriptome at isoform resolution. Here the authors develop scRCAT-seq to characterize the 5′- and 3′-ends of transcripts in single cells, and identify cell-type specif
Externí odkaz:
https://doaj.org/article/55349467bece45359095ffc399cb00a2
Publikováno v:
Cells, Vol 11, Iss 19, p 3146 (2022)
Retinal degenerative diseases are frequently caused by the loss of retinal neural cells such as photoreceptors. Cell replacement is regarded as one of the most promising therapies. Multiple types of stem and somatic cells have been tested for photore
Externí odkaz:
https://doaj.org/article/33bc73a228764d1aabcb626af77f6e98
Autor:
Yang Song, Jennifer Soto, Pingping Wang, Qin An, Xuexiang Zhang, SoonGweon Hong, Luke P. Lee, Guoping Fan, Li Yang, Song Li
Publikováno v:
Advanced Science, Vol 8, Iss 7, Pp n/a-n/a (2021)
Abstract Cell reprogramming is considered a stochastic process, and it is not clear which cells are prone to be reprogrammed and whether a deterministic step exists. Here, asymmetric cell division (ACD) at the early stage of induced neuronal (iN) rep
Externí odkaz:
https://doaj.org/article/167e49671f404884894d6e34b3e88d02