Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Guomin Ou"'
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Hepatitis B surface antigen (HBsAg) consists of six components of large/middle/small HBs proteins (L/M/SHBs) with non-glycosylated (ng)- or glycosylated (g)- isomers at sN146 in their shared S domain. g-SHBs plays a crucial role i
Externí odkaz:
https://doaj.org/article/6c51a58d3151446884b7fd5d9f2f6428
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102317- (2023)
Summary: Exploring the essential role of Importin 11 (IPO11) in the nuclear translocation of its potential cargo proteins requires an efficient means of IPO11 deletion and re-expression. Here, we present a protocol for the generation of IPO11 deletio
Externí odkaz:
https://doaj.org/article/d90d9cb8ff464bb0868ea2a461a4566f
Autor:
Yarui Zhang, Guomin Ou, Zhujing Ye, Zhou Zhou, Qianlin Cao, Mengting Li, Jingdong Wang, Jianping Cao, Hongying Yang
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105115- (2022)
Summary: How the ataxia telangiectasia mutated (ATM) protein kinase, a core protein in DNA damage response, is regulated at post-transcription level remains unclear. Here it is identified that protein Reprimo (RPRM) downregulates ATM protein levels,
Externí odkaz:
https://doaj.org/article/e2b3eee6525b4b0888f856461b6206c8
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 5, p 260 (2023)
Concentrated growth factors (CGFs) are widely used in surgery with bone grafting, but the release of growth factors from CGFs is rapid. RADA16, a self-assembling peptide, can form a scaffold that is similar to the extracellular matrix. Based on the p
Externí odkaz:
https://doaj.org/article/efa47cca481046e3ad60fdc7e1f37f85
Autor:
Yiwei Xiao, Junning Cao, Ze Zhang, Chaoting Zeng, Guomin Ou, Jihang Shi, Zhixiu Liu, Yi Li, Juan Deng, Yinzhe Xu, Wenwen Zhang, Jie Li, Tong Li, Hui Zhuang, Shichun Lu, Kuanhui Xiang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundThe existence of hepatic cancer stem cells (CSCs) contributes to chemotherapy resistance and cancer recurrence after treatment or surgery. However, very little is known about the hepatitis B virus (HBV) replication and its relationship with
Externí odkaz:
https://doaj.org/article/96341a9f6b4c48f69acdaeff77c32ca3
Autor:
Dingjie Wang, Xingting Han, Feng Luo, Florian M. Thieringer, Yichen Xu, Guomin Ou, Sebastian Spintzyk
Publikováno v:
Journal of Functional Biomaterials, Vol 13, Iss 4, p 288 (2022)
Three-dimensionally printed polyetheretherketone (PEEK) materials are promising for fabricating customized dental abutments. This study aimed to investigate the adhesive property of a 3D-printed PEEK material. The effects of surface treatment and tem
Externí odkaz:
https://doaj.org/article/c949b6c9f7724f429876c593a3f73238
Autor:
Yuan Wang, Peng Deng, Yuting Liu, Yunshu Wu, Yaqian Chen, Yuchen Guo, Shiwen Zhang, Xiaofei Zheng, Liyan Zhou, Weiqing Liu, Qiwen Li, Weimin Lin, Xingying Qi, Guomin Ou, Cunyu Wang, Quan Yuan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
α-ketoglutarate is an intermediate of the Krebs Cycle that was recently reported to extend lifespan in C.Elegans. Here, the authors show that administration of α-ketoglutarate to mice reduces age-related bone loss, by ameliorating senescence of bon
Externí odkaz:
https://doaj.org/article/c0e3afcbf66046cca618c00251e8fdd0
Autor:
Guomin Ou, Lingyuan He, Luwei Wang, Ji Song, Xinyuan Lai, Xing Tian, Lei Wang, Kai Zhang, Xuechao Zhang, Juan Deng, Hui Zhuang, Kuanhui Xiang, Tong Li
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Genetic variability has significant impacts on biological characteristics and pathogenicity of hepatitis B virus (HBV), in which the N-terminal sequence of the presurface 1 (preS1) region of HBV large surface protein (LHBs) displays genotype (GT) dep
Externí odkaz:
https://doaj.org/article/9ea35cfd687f44c2b6843407e57900f8
Autor:
Xiaofei Zheng, Shiwen Zhang, Guomin Ou, Peng Deng, Yunshu Wu, Cun-Yu Wang, Qiwen Li, Yuchen Guo, Y. Chen, Quan Yuan, Yuting Liu, Xingying Qi, Weiqing Liu, Yuan Wang, Liyan Zhou, Weimin Lin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Age-related osteoporosis is characterized by the deterioration in bone volume and strength, partly due to the dysfunction of bone marrow mesenchymal stromal/stem cells (MSCs) during aging. Alpha-ketoglutarate (αKG) is an essential intermediate in th
Autor:
Xing Tian, Huijun Dong, Xinyuan Lai, Guomin Ou, Junning Cao, Jihang Shi, Chengang Xiang, Lei Wang, Xuechao Zhang, Kai Zhang, Ji Song, Juan Deng, Hongkui Deng, Shichun Lu, Hui Zhuang, Tong Li, Kuanhui Xiang
Publikováno v:
Antiviral research. 207
Members of the tripartite motif (TRIM) protein family strongly induced by interferons (IFNs) are parts of the innate immune system with antiviral activity. However, it is still unclear which TRIMs could play important roles in hepatitis B virus (HBV)