Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Guolong Gu"'
Autor:
Xing Chen, Xiang Ling, Jiaxuan Xia, Ying Zhu, Longlong Zhang, Yuwei He, Anni Wang, Guolong Gu, Bo Yin, Jianxin Wang
Publikováno v:
Bioactive Materials, Vol 15, Iss , Pp 15-28 (2022)
The cytomembrane-derived delivery platform represents a promising biomimetic strategy in oncotherapy. To achieve durable and reliable tumor inhibition, mature dendrosomes (mDs), which were isolated from bone marrow-derived dendritic cells undergoing
Externí odkaz:
https://doaj.org/article/7a5d129675ba40c1bdc14f98dafd52ce
Autor:
Sunhui Chen, Qiujun Qiu, Dongdong Wang, Dejun She, Bo Yin, Guolong Gu, Meihong Chai, Dong Nyoung Heo, Huining He, Jianxin Wang
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 349
Local treatment after resection to inhibit glioma recurrence is thought to able to meet the real medical needs. However, the only clinically approved local glioma treatment-wafer containing bis(2-chloroethyl) nitrosourea (BCNU) showed very limited ef
Autor:
Jiaxuan Xia, Shaojie Ma, Xi Zhu, Chen Chen, Ru Zhang, Zhonglian Cao, Xing Chen, Longlong Zhang, Ying Zhu, Shuya Zhang, Shiyi Li, Guolong Gu, Xunbin Wei, Kunqian Yu, Jianxin Wang
Publikováno v:
Science Advances. 8
Limited circulating tumor cells (CTCs) capturing efficiency and lack of regulation capability on CTC-supportive metastatic niches (MNs) are two main obstacles hampering the clinical translation of conventional liposomes for the treatment of metastati
Publikováno v:
ACS applied materialsinterfaces. 13(43)
Drug resistance and the serious side effects caused by classical chemotherapy drugs necessitate the development of novel targeted drug delivery systems. The high lipophilicity and short half-life of nitric oxide (NO), a gas with strong antitumor acti
Autor:
Xing Chen, Xiang Ling, Jiaxuan Xia, Ying Zhu, Longlong Zhang, Yuwei He, Anni Wang, Guolong Gu, Bo Yin, Jianxin Wang
Publikováno v:
Bioactive materials. 15
The cytomembrane-derived delivery platform represents a promising biomimetic strategy in oncotherapy. To achieve durable and reliable tumor inhibition, mature dendrosomes (mDs), which were isolated from bone marrow-derived dendritic cells undergoing
Publikováno v:
Bioorganic chemistry. 115
Farnesoid X receptor (FXR) has been considered as an attractive target for metabolic disorder and liver injury, while many current FXR agonists suffer from undesirable side effects, such as pruritus. Therefore, it is urgent to develop new structure t
Publikováno v:
Applied Sciences, Vol 14, Iss 3, p 1055 (2024)
The instability of slopes and ground subsidence caused by the conversion from open-pit to underground mining are important aspects of mining disaster research. This study focuses on the instability of slopes and ground subsidence during the conversio
Externí odkaz:
https://doaj.org/article/71714596516d492ab584be9388504ba2
Publikováno v:
Chemical Biology & Drug Design. 83:324-333
Poor water solubility limits the clinical use of andrographolide and its derivatives. In an attempt to develop potent hepatoprotective drugs, a strategy was proposed to improve the aqueous solubility of andrographolide. Ten andrographolide derivative
Autor:
Xuekun Wang, Guolong Gu, Hai Qian, Chunlei Tang, Wenlong Huang, Baowei Yang, Jing Li, Xiaoyun Zhu
Publikováno v:
Letters in Drug Design & Discovery. 11:677-685
Autor:
Meng Ru, Wenlong Huang, Baowei Yang, Hai Qian, Xuekun Wang, Sijia Yan, Xin Deng, Wei Chen, Hong Chen, Jing Jin, Guolong Gu, Yicheng Mei
Publikováno v:
Chemical Biology & Drug Design. 82:99-105
Diabetes mellitus has been considered as a major health problem in the world today. This study aimed to investigate the hypoglycemic and antioxidative effects of peptide MC62 which was synthesized by solid-phase peptide synthesis method against diabe