Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Guolin Shen"'
Autor:
Longhao Cheng, Xiaoxue Wang, Aijun Liu, Ying Zhu, Hu Cheng, Jiangling Yu, Lili Gong, Honglin Liu, Guolin Shen, Lihong Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3493-3512 (2024)
Amino acid metabolic remodeling is a hallmark of cancer, driving an increased nutritional demand for amino acids. Amino acids are pivotal for energetic regulation, biosynthetic support, and homeostatic maintenance to stimulate cancer progression. How
Externí odkaz:
https://doaj.org/article/6bbd17712b8949efb459534917975d92
Autor:
Guolin Shen, Jintao Zhang
Publikováno v:
Revista Teknokultura, Vol 20, Iss Special Issue (2023)
Platforms have emerged as the dominant mode of communication in China, empowering individuals to express their opinions and question the authority and credibility of the ruling party. To illustrate the impact of platforms on Party-government relation
Externí odkaz:
https://doaj.org/article/668c03ec2dec49bdba7b920a13f0d42f
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 2, Iss 2, Pp 174-180 (2012)
Thienorphine (TNP) is a new partial opioid agonist currently developed as a promising drug candidate with the intended clinical indication for the treatment of opioid dependence. The pharmacokinetic profile and biliary excretion of TNP and its glucur
Externí odkaz:
https://doaj.org/article/49902e8116df4dc7adc0127f2c65cc6e
Autor:
Naining Song, Haishan Li, Hainan Ji, Chan Zhao, Baoliang Xu, Chang Liu, Na Tong, Hua Li, Guolin Shen
Publikováno v:
Toxicol Res (Camb)
Air Potato Yam is widely used in the treatment of many conditions such as cancer, inflammation, and goiter. Diosbulbin B (DIOB) is the primary active component of Air Potato Yam, and it exhibits anti-tumor and anti-inflammatory properties. The main p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4e886c8d7ea111da375b0890b08d87
https://doi.org/10.1093/toxres/tfab014
https://doi.org/10.1093/toxres/tfab014
Autor:
Lei Zhang, Juan Ren, Hua Li, Guolin Shen, Baoliang Xu, Naining Song, Wentao Li, Hainan Ji, Haishan Li
Publikováno v:
Chemical Research in Toxicology. 33:1389-1402
Diosbulbin B (DIOB) is an effective component of air potato yam with antitumor and anti-inflammatory activities, and it is the main toxic component leading to hepatotoxicity. However, the mechanism of its hepatotoxicity remains unclear. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a3d9c225067f76cfcdf5241a5642ae
https://doi.org/10.1021/acs.chemrestox.9b00503
https://doi.org/10.1021/acs.chemrestox.9b00503
Publikováno v:
Journal of Ethnopharmacology. 301:115801
The processed lateral root of Aconitum carmichaelii Debx. is known as Fuzi, an extensively used Traditional Chinese Medicine to treat cardiovascular diseases, rheumatism arthritis, bronchitis, pains, and hypothyroidism, etc. Although Chinese Pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbf269e9a658e406ead74b471413375
https://doi.org/10.1016/j.jep.2022.115801
https://doi.org/10.1016/j.jep.2022.115801
Autor:
Haishan Li, Zhenqing Zhang, Juan Ren, Xiaomei Zhuang, Wenping Xie, Wenpeng Zhang, Wentao Li, Guolin Shen, Mengyang Chang, Huiming Chen
Publikováno v:
Toxicology Letters. 299:76-85
This study combined metabonomics with molecular biology techniques to identify differential endogenous substances produced by triclocarban (TCC) that affect plasma and liver metabolism in mice, to map their associated metabolic pathways, and to syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6785cf56ce0d4671948eb6666ae81bdc
https://doi.org/10.1016/j.toxlet.2018.09.011
https://doi.org/10.1016/j.toxlet.2018.09.011
Autor:
Wenping Xie, Xiaomei Zhuang, Wenlian Yu, Yuan Cui, Wentao Li, Zhenqing Zhang, Wenpeng Zhang, Huiming Chen, Haishan Li, Guolin Shen, Juan Ren, Lili Zhou
Publikováno v:
Journal of Agricultural and Food Chemistry. 66:1533-1542
Triclocarban (TCC) has been identified as a new environmental pollutant that is potentially hazardous to human health; however, the effects of short-term TCC exposure on cardiac function are not known. The aim of this study was to use metabonomics an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a77dc9e6b1d9ff1ad51bcbc77a321ee
https://doi.org/10.1021/acs.jafc.7b05220
https://doi.org/10.1021/acs.jafc.7b05220
Publikováno v:
The Science of the total environment. 703
Bisphenol-A (BPA) is a representative environmental endocrine disrupting chemical that is widely used in the production of polycarbonate plastics and epoxy resins. Many studies have confirmed BPA to be closely associated with metabolic diseases, repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f314294d3125208722bb0ef7448e1467
https://pubmed.ncbi.nlm.nih.gov/31715463
https://pubmed.ncbi.nlm.nih.gov/31715463
Autor:
Baoliang Xu, Aihua Liang, Guolin Shen, Jiayin Han, Juan Ren, Huiming Chen, Yuan Cui, Haishan Li, Naining Song
Publikováno v:
Toxicology and applied pharmacology. 373
As the main toxic component of aristolochic acid, aristolochic acid I (AAI) is primarily found in Aristolochiaceae plants such as Aristolochia, Aristolochia fangchi and Caulis aristolochiae manshuriensis. AAI has been proven to be carcinogenic, mutag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155347172cf615aad0926a8d8d6150ff
https://pubmed.ncbi.nlm.nih.gov/31009690
https://pubmed.ncbi.nlm.nih.gov/31009690