Zobrazeno 1 - 10
of 1 480
pro vyhledávání: '"Guoliang Zhang"'
Autor:
Gongxun Tan, Bingquan Jin, Xiaoqin Qian, Yuguo Wang, Guoliang Zhang, Enock Adjei Agyekum, Feng Wang, Liang Shi, Yue Zhang, Zhenwei Mao, Chunhe Shi, Ying Xu, Xiuying Li, Lele Zhang, Shaohua Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Telomerase reverse transcriptase promoter (TERTp) mutations are associated with non-radioiodine avidity. However, the role of these mutations in the clinical outcomes of patients with radioiodine-refractory differentiated thyroid cancer (RAI
Externí odkaz:
https://doaj.org/article/0d87f4f3035046e9931051e01beef8b0
Autor:
Lanxin Li, Chenyang Liu, Rui Wang, Xiaolin Yang, Xiangkai Wei, Chunhong Chu, Guoliang Zhang, Chenxue Liu, Wenrui Cui, Huixia Xu, Ke Wang, Lei An, Xiaodong Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Mutations in the epidermal growth factor receptor (EGFR) gene are common driver oncogenes in non-small cell lung cancer (NSCLC). Studies have shown that afatinib is beneficial for NSCLC patients with rare EGFR mutations. However, the effecti
Externí odkaz:
https://doaj.org/article/6abc094645bc4bc3b405fbf30c38e053
Autor:
Wenxiao Yang, Luo Hong, Linwei Guo, Yunjin Wang, Xiangchen Han, Boyue Han, Zheng Xing, Guoliang Zhang, Hongxia Zhou, Chao Chen, Hong Ling, Zhimin Shao, Xin Hu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Metabolic dysregulation is prominent in triple-negative breast cancer (TNBC), yet therapeutic strategies targeting cancer metabolism are limited. Here, utilizing multiomics data from our TNBC cohort (n = 465), we demonstrated widespread spli
Externí odkaz:
https://doaj.org/article/bb71fcc031d749468d9f4cd409564d0d
Autor:
Fusheng Yao, Ruiqi Zhang, Qiao Lin, Hui Xu, Wei Li, Min Ou, Yiting Huang, Guobao Li, Yuzhong Xu, Jiaping Song, Guoliang Zhang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Tuberculosis (TB) remains one of the deadliest chronic infectious diseases globally. Early diagnosis not only prevents the spread of TB but also ensures effective treatment. However, the absence of non-sputum-based diagnostic tests often leads to del
Externí odkaz:
https://doaj.org/article/e23f4003be944c2eab387bb9185d396c
Autor:
Dongxin Liu, Fei Huang, Yaru Li, Lingfeng Mao, Wencong He, Sihao Wu, Hui Xia, Ping He, Huiwen Zheng, Yang Zhou, Bing Zhao, Xichao Ou, Yuanyuan Song, Zexuan Song, Li Mei, Li Liu, Guoliang Zhang, Qiang Wei, Yanlin Zhao
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTChina, with the third largest share of global tuberculosis cases, faces a substantial challenge in its healthcare system as a result of the high burden of multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB). This study emplo
Externí odkaz:
https://doaj.org/article/fe0acb32c22b47049e29714030cb7e20
Publikováno v:
Journal of Chemical Engineering of Japan, Vol 57, Iss 1 (2024)
AbstractA kind of highly dispersed ZrO2 modified Cs/SiO2-based catalyst was prepared via ligand–assisted impregnation strategy. The catalyst was then used to the aldol condensation reaction of methyl acetate (MAc) with formaldehyde (FA) to produce
Externí odkaz:
https://doaj.org/article/f31be7b8ac8e4ba2b293674a4a5dc7c8
Autor:
Jing Yang, Jinman Li, Linfeng Zhang, Zijie Shen, Yan Xiao, Guoliang Zhang, Mingwei Chen, Fuhui Chen, Ling Liu, Ying Wang, Lan Chen, Xinming Wang, Li Zhang, Lu Wang, Zhang Wang, Jianwei Wang, Mingkun Li, Lili Ren
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Community-acquired pneumonia (CAP) is a common and serious condition that can be caused by a variety of pathogens. However, much remains unknown about how these pathogens interact with the lower respiratory commensals, and whether
Externí odkaz:
https://doaj.org/article/0417c9675cd24105af359a07b0a86717
Autor:
Dayong Zheng, Yan Zhang, Sukjin Yang, Ning Su, Michael Bakhoum, Guoliang Zhang, Samira Naderinezhad, Zhengmei Mao, Zheng Wang, Ting Zhou, Wenliang Li
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Although effective initially, prolonged androgen deprivation therapy (ADT) promotes neuroendocrine differentiation (NED) and prostate cancer (PCa) progression. It is incompletely understood how ADT transcriptionally induces NE genes in PCa c
Externí odkaz:
https://doaj.org/article/90b69f9b55bf4bdc9486b4db44b5ad47
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Low sperm motility is a significant contributor to male infertility. beta-defensins have been implicated in host defence and the acquisition of sperm motility; however, the regulatory mechanisms governing their gene expression patterns and f
Externí odkaz:
https://doaj.org/article/f104bfebbefd428792bd64fc16e582b7
Autor:
Chao Huang, Xiaoxia Li, Hanqing Li, Ruolan Chen, Zhaoqing Li, Daisong Li, Xiaojian Xu, Guoliang Zhang, Luning Qin, Bing Li, Xian-Ming Chu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Doxorubicin (DOX) is a broad-spectrum and highly efficient anticancer agent, but its clinical implication is limited by lethal cardiotoxicity. Growing evidences have shown that alterations in intestinal microbial composition and function, na
Externí odkaz:
https://doaj.org/article/5175a83b49fa4b148a6c297a8529fd7d