Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Guojuan, Pu"'
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
The application of ketoconazole (KET) in ocular drug delivery is restricted by its poor aqueous solubility though its broad-spectrum antifungal activity. The aim of this study is to develop an ion-sensitive in situ gel (ISG) of KET to promote its ocu
Externí odkaz:
https://doaj.org/article/a6661559ca6046229fb77cb264057066
Autor:
Qing Luo, Jingjing Yang, Haohang Xu, Jieran Shi, Zhen Liang, Rui Zhang, Ping Lu, Guojuan Pu, Ningmin Zhao, Junjie Zhang
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 837-855 (2022)
Sorafenib (SRB), a multikinase inhibitor, is effective in reducing experimental corneal neovascularization (CNV) after oral administration; however, its therapeutic use in ocular surface disorders is restricted due to poor solubility and limited bioa
Externí odkaz:
https://doaj.org/article/4f80e1ddb79d4844873fe6cdd1f4a282
Autor:
Enming Du, Guojuan Pu, Siyu He, Fangyuan Qin, Yange Wang, Gang Wang, Zongming Song, Junjie Zhang, Ye Tao
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Excessive UV-B exposure is well known to be a risk factor for corneal phototoxicity including direct DNA damage and disturbances in the antioxidant balance. Here, we showed a successful synthesis of a water-soluble and biocompatible small molecule DH
Externí odkaz:
https://doaj.org/article/d0913c692d0a42d48a78573fd73b168c
Autor:
Youzhi Wang, Guojuan Pu, Yang Shi, Ling Wang, Huae Xu, Zhimou Yang, Siwan Wang, Yaoxia Chen, Xinxin Li, Chunhui Liang
Publikováno v:
Nanoscale. 12:2111-2117
The development of molecules with immune stimulatory properties is crucial for cancer immunotherapy. In this work, we combined two peptide-based molecules, tuftsin (TKPR) and Nap-GDFDFDY, to develop a novel self-assembling molecule Nap-GDFDFDYTKPR (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0becc1aed5cae05e06a4caef6aea4b92
https://doi.org/10.1039/c9nr08916k
https://doi.org/10.1039/c9nr08916k
Autor:
Xinxin, Li, Youzhi, Wang, Siwan, Wang, Chunhui, Liang, Guojuan, Pu, Yaoxia, Chen, Ling, Wang, Huae, Xu, Yang, Shi, Zhimou, Yang
Publikováno v:
Nanoscale. 12(3)
The development of molecules with immune stimulatory properties is crucial for cancer immunotherapy. In this work, we combined two peptide-based molecules, tuftsin (TKPR) and Nap-GDFDFDY, to develop a novel self-assembling molecule Nap-GDFDFDYTKPR (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a12817474becc3260da7fb8889ad883
https://pubmed.ncbi.nlm.nih.gov/31913398
https://pubmed.ncbi.nlm.nih.gov/31913398
Autor:
Yumin Zhang, Yang Gao, Jianfeng Liu, Zhimou Yang, Cuihong Yang, Chunhua Ren, Jinjian Liu, Lijun Yang, Fan Huang, Guojuan Pu
Publikováno v:
Journal of Biomedical Nanotechnology. 14:1125-1134
Supramolecular nanofibers based on D-amino acid-containing peptide self-assembly have attracted increased interest recently because of their superior biostability. However, the construction of nanostructures containing D-amino acids is still insuffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd12c5f2b0193f831693e85f318bec2f
https://doi.org/10.1166/jbn.2018.2564
https://doi.org/10.1166/jbn.2018.2564
Autor:
Xingyi Li, Shuai Shi, Zhifen He, Hao Chen, Guojuan Pu, Jing Yu, Wenguang Zhao, Zichao Luo, Xinxin Yu
Publikováno v:
RSC Advances. 6:62434-62438
A supramolecular hydrogel based on a peptide (GFFY) and non-steroidal anti-inflammatory drugs (naproxen and ibuprofen) was synthesized for use as a topical gel. Using a heating–cooling strategy, the drug–peptide derivatives could self-assemble in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9670d934f5585b6b2e7cd4c750bb5887
https://doi.org/10.1039/c6ra09615h
https://doi.org/10.1039/c6ra09615h
Autor:
Hao Chen, Zhaoliang Zhang, Xingyi Li, Shuai Shi, Guojuan Pu, Renlong Liang, Wei Wu, Jing Yu, Zichao Luo
Publikováno v:
RSC Advances. 6:76093-76098
Conventional ophthalmic formulations such as eye drops normally suffer from limited therapeutic efficacy with a requirement for frequent instillation. To improve convenience and efficacy, a peptide-based supramolecular hydrogel (Nap-GFFY) was fabrica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6384f3abc427100a502a3522c29e7b71
https://doi.org/10.1039/c6ra11691d
https://doi.org/10.1039/c6ra11691d
Autor:
Yumiao Chen, Tengyan Xu, Lina Wang, Chunhui Liang, Debing Zheng, Huaimin Wang, Guojuan Pu, Zhimou Yang, Yaoxia Chen
Publikováno v:
Applied Materials Today. 21:100855
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b3bd943b294cd9da5f1ef661c954d0
https://doi.org/10.1016/j.apmt.2020.100855
https://doi.org/10.1016/j.apmt.2020.100855
Autor:
Guojuan Pu, Lina Wang, Huaimin Wang, Debing Zheng, Yumiao Chen, Yaoxia Chen, Chunhui Liang, Tengyan Xu, Zhimou Yang
Publikováno v:
Applied Materials Today. 20:100787
Constructing supramolecular structures via non-covalent interactions depends on the assembly pathway selection, which has attracted much interest in chemistry, materials science, and nanomedicine. Despite recent advances in the formation of a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b431d7a0ed3bf341782e79aed3dfd5a3
https://doi.org/10.1016/j.apmt.2020.100787
https://doi.org/10.1016/j.apmt.2020.100787