Zobrazeno 1 - 2
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pro vyhledávání: '"Guoju Geng"'
Publikováno v:
Bioanalysis.
Background: Monitoring levels of endogenous biomarkers has become an alternative approach to assess transporter-mediated drug–drug interactions in clinical trials. Among the biomarkers of interest, kynurenic acid is effective for the human organic
Autor:
Eric B. Lansdon, Helen Yu, Kropf Jeffrey E, Peter A. Blomgren, Jennifer R. Lo, Guoju Geng, Kevin S. Currie, Aaron C. Schmitt, Jayaraman Chandrasekhar, Chris Pohlmeyer, Scott A. Mitchell, Seung H. Lee, Wanchi Fung, Sarah Wise, Jin-Ming Xiong, Zhongdong Zhao, Randall Mark Jones, Kimberly Suekawa-Pirrone, Julie Di Paolo, Bernard P. Murray, Carmen Ip, Jianjun Xu
Publikováno v:
ACS Med Chem Lett
[Image: see text] Spleen tyrosine kinase (SYK) is a critical regulator of signaling in a variety of immune cell types such as B-cells, monocytes, and macrophages. Accordingly, there have been numerous efforts to identify compounds that selectively in