Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Guojie Ho"'
Autor:
Jen-Chieh Tseng, Nara Narayanan, Guojie Ho, Kevin Groves, Jeannine Delaney, Bagna Bao, Jun Zhang, Jeffrey Morin, Sylvie Kossodo, Milind Rajopadhye, Jeffrey D Peterson
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182689 (2017)
Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models. However, it is relatively insensitive, and often requires long treatment courses to achieve gr
Externí odkaz:
https://doaj.org/article/004dc262c9164482acf31b352bed2c16
Autor:
Jeannine Delaney, Bagna Bao, Jeffrey D. Peterson, Guojie Ho, Milind Rajopadhye, Jun Zhang, Kristine O. Vasquez
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 370:288-298
In mouse pharmacokinetic (PK) studies, current standard methods often require large numbers of animals to support collection of blood samples serially over a defined time range. We have developed and validated a non-invasive fluorescence molecular to
Autor:
Jun Zhang, Milind Rajopadhye, Nara Narayanan, Jeannine Delaney, Kevin Groves, Bagna Bao, Guojie Ho, Jeffrey D. Peterson, Jen-Chieh Tseng, Sylvie Kossodo, Jeffrey Morin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0182689 (2017)
PLoS ONE, Vol 12, Iss 8, p e0182689 (2017)
Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models. However, it is relatively insensitive, and often requires long treatment courses to achieve gr
Autor:
Sylvie Kossodo, Wael Yared, Jeffrey D. Peterson, Milind Rajopadhye, Jeffrey Morin, Jeannine Delaney, Guojie Ho
Publikováno v:
Cancer Research. 74:4939-4939
Prostate-Specific Antigen (PSA) is a 237 amino acid, 33 kDa, extracellular serine protease expressed in prostate epithelial tissue. In the normal prostate, high concentrations of PSA are stored in the prostatic ductal network. However, cancer leads t
Autor:
Milind Rajopadhye, Jeffrey Morin, Garry Cuneo, Jeffrey D. Peterson, Guojie Ho, Wael Yared, Jeannine Delaney, Sylvie Kossodo
Publikováno v:
Journal of biomedical optics. 18(10)
Assays for blood levels of prostate-specific antigen (PSA), performed in prostate cancer detection, measure mostly inactive/complexed PSA and do not provide information regarding enzymatically active PSA, which is biologically more relevant. Thus, we
Autor:
Jayme Jensen, Maureen Pickarski, Guojie Ho, Cyrille Sur, Le Thi Duong, Alexa Gleason, Jun Zhang, Garry Cuneo, Bohumil Bednar, Renee C. Gaspar, Milind Rajopadhye, Shu-An Lin, Wael Yared, George D. Hartman, Chiara Buono, Agnieszka Blusztajn, Richard Hargreaves, Paul J. Coleman, Jeffrey D. Peterson, Sylvie Kossodo
Publikováno v:
Molecular imaging and biology. 12(5)
Integrins, especially α(v)β(3) and α(v)β(5), are upregulated in tumor cells and activated endothelial cells and as such, serve as cancer biomarkers. We developed a novel near-infrared-labeled optical agent for the in vivo detection and quantifica
Autor:
Guojie Ho, Morin, Jeffrey, Delaney, Jeannine, Cuneo, Garry, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D., Kossodo, Sylvie
Publikováno v:
Journal of Biomedical Optics; Oct2013, Vol. 18 Issue 10, p1-8, 8p
Autor:
Jeffrey Morin, Garry Cuneo, Jeannine Delaney, Wael Yared, Guojie Ho, Sylvie Kossodo, Milind Rajopadhye, Jeffrey D. Peterson
Publikováno v:
Cancer Research. 72:LB-511
Tumors induce significant blood vessel development in order to support their aggressive growth and progression, and the extensive and disordered nature of tumor vasculature impairs drug delivery and efficacy. Destroying the tumor vasculature and/or i
Autor:
Tseng, Jen-Chieh1 Jen-Chieh.Tseng@perkinelmer.com, Narayanan, Nara1, Ho, Guojie1, Groves, Kevin1, Delaney, Jeannine1, Bao, Bagna1, Zhang, Jun1, Morin, Jeffrey1, Kossodo, Sylvie1, Rajopadhye, Milind1, Peterson, Jeffrey D.1
Publikováno v:
PLoS ONE. 8/8/2017, Vol. 12 Issue 8, p1-21. 21p.