Zobrazeno 1 - 10
of 809
pro vyhledávání: '"Guohua Zhao"'
Autor:
Xiaoli Si, Shaobing Dai, Yi Fang, Jiahui Tang, Zhiyun Wang, Yaolin Li, Zhe Song, Ying Chen, Yi Liu, Guohua Zhao, Baorong Zhang, Jiali Pu
Publikováno v:
Journal of Advanced Research, Vol 56, Iss , Pp 125-136 (2024)
Introduction: The glymphatic system offers a perivascular pathway for the clearance of pathological proteins and metabolites to optimize neurological functions. Glymphatic dysfunction plays a pathogenic role in Parkinson's disease (PD); however, the
Externí odkaz:
https://doaj.org/article/272ddf559a2c400fa580384519b9514c
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33617- (2024)
Using Tyrosine Kinase Inhibitors (TKIs) for gastrointestinal stromal tumors (GIST) has significantly reduced the risk of recurrence and prolonged survival. Immunotherapy has demonstrated efficacy in multiple solid tumors, but its effectiveness in GIS
Externí odkaz:
https://doaj.org/article/91be74ac9ef549289e6363533aab09b1
Autor:
Jie Bai, Mengyang He, Eryuan Gao, Guang Yang, Hongxi Yang, Jie Dong, Xiaoyue Ma, Yufei Gao, Huiting Zhang, Xu Yan, Yong Zhang, Jingliang Cheng, Guohua Zhao
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background We created discriminative models of different regions of interest (ROIs) using radiomic texture features of neurite orientation dispersion and density imaging (NODDI) and evaluated the feasibility of each model in differentiating
Externí odkaz:
https://doaj.org/article/0c7bf09e974648f4bc900a8df1b457a3
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Neoadjuvant therapy has been widely employed in the treatment of rectal cancer, demonstrating its utility in reducing tumor volume, downstaging tumors, and improving patient prognosis. It has become the standard preoperative treatment modality for lo
Externí odkaz:
https://doaj.org/article/3a6e581120414c76b441f479dbbaa5bd
Publikováno v:
Food Chemistry: X, Vol 21, Iss , Pp 101134- (2024)
Apple peel is a typical lignocellulosic food by-product rich in functional components. In this work, apple peel was solid-state fermented with Aspergillus oryzae with an aim to modulate its composition and bioactivity. The results showed that A. oryz
Externí odkaz:
https://doaj.org/article/82111ebbbaf34214a0f28de425757c19
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Pancreatic cancer, an exceptionally malignant tumor of the digestive system, presents a challenge due to its lack of typical early symptoms and highly invasive nature. The majority of pancreatic cancer patients are diagnosed when curative surgical re
Externí odkaz:
https://doaj.org/article/60df52a499d1446cb7b517c1e9fe4e32
Autor:
Fangchao Wu, Junling Zhang, Qian Wang, Wenxin Liu, Xinlei Zhang, Fangli Ning, Mengmeng Cui, Lei Qin, Guohua Zhao, Di Liu, Shi Lv, Yuzhen Xu
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26304- (2024)
Objective: Dysregulation of the immune system plays a vital role in the pathological process of vascular dementia, and this study aims to spot critical biomarkers and immune infiltrations in vascular dementia employing a bioinformatics approach. Meth
Externí odkaz:
https://doaj.org/article/d423f7c2f5624db4a7103f902e7cefff
Autor:
Demin Ma, Yueming Zheng, Xiaoxiao Li, Xiaoyu Zhou, Zhenni Yang, Yan Zhang, Long Wang, Wenbo Zhang, Jiajia Fang, Guohua Zhao, Panpan Hou, Fajun Nan, Wei Yang, Nannan Su, Zhaobing Gao, Jiangtao Guo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The human voltage-gated potassium channel KCNQ2/KCNQ3 carries the neuronal M-current, which helps to stabilize the membrane potential. KCNQ2 can be activated by analgesics and antiepileptic drugs but their activation mechanisms remain unclea
Externí odkaz:
https://doaj.org/article/9b35c0fc9ccb4882a2c41a9d66f6e062
Autor:
Wenlin Zhang, Yang Yang, Xuedong Zhu, Suyu Yang, Ximei Liao, Honglei Li, Zhexin Li, Qinhong Liao, Jianmin Tang, Guohua Zhao, Lin Wu
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background As the characteristic functional component in ginger, gingerols possess several health-promoting properties. Long non-coding RNAs (lncRNAs) act as crucial regulators of diverse biological processes. However, lncRNAs in ginger are
Externí odkaz:
https://doaj.org/article/8948a84776184db39fa44121fc9671f6
Autor:
Kai Zhao, Ankang Gao, Eryuan Gao, Jinbo Qi, Ting Chen, Guohua Zhao, Gaoyang Zhao, Peipei Wang, Weijian Wang, Jie Bai, Yong Zhang, Huiting Zhang, Guang Yang, Xiaoyue Ma, Jingliang Cheng
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
Background and purposeThe differential diagnosis between solid glioma and brain inflammation is necessary but sometimes difficult. We assessed the effectiveness of multiple diffusion metrics of diffusion-weighted imaging (DWI) in differentiating soli
Externí odkaz:
https://doaj.org/article/b204c4183bd04eeabfaeb5a693e1d062