Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Guogui Sun"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 8, Pp 565-578 (2024)
Background and objective Isoliquiritigenin (ISL) is an important pharmacological constituent of Glycyrrhiza glabra, which possesses a range of physiological and pharmacological activities, as well as significant antitumor activity, and can be used as
Externí odkaz:
https://doaj.org/article/548662078b404053ab29a284a815152e
Autor:
Zhihao Lu, Li Kong, Buhai Wang, Junye Wang, Lianke Liu, Yongqian Shu, Lei Yang, Guogui Sun, Guochun Cao, Yinghua Ji, Tongjian Cui, Hu Liu, Wensheng Qiu, Na Li, Gaofeng Li, Hui Luo, Xinfang Hou, Yanqiao Zhang, Wenbin Yue, Liying Xue, Zheng Liu, Yueyin Pan, Shegan Gao, Xiuwen Wang, Zhanyu Pan, Shuqun Zhang, Gen Lin, Yanru Xie, Kangsheng Gu, Tiejun Ren, Weidong Li, Tao Li, Shoufeng Wang, Wei He, Yun Fan, Jun Liang, Bing Xia, Li Zhao, Shuxuan Wang, Lin Shen
Publikováno v:
EClinicalMedicine, Vol 72, Iss , Pp 102623- (2024)
Summary: Background: In ORIENT-15 study, sintilimab plus chemotherapy demonstrated significant improvement on overall survival (OS) versus placebo plus chemotherapy in first-line treatment of advanced esophageal squamous cell carcinoma (ESCC). Here,
Externí odkaz:
https://doaj.org/article/3439ece3dd7b46968792b2d1c86fbbe8
Autor:
Jin Li, Shukui Qin, Lu Wen, Junsheng Wang, Wenying Deng, Weijian Guo, Tongfu Jia, Da Jiang, Guifang Zhang, Yifu He, Yi Ba, Haijun Zhong, Lin Wang, Xiaoyan Lin, Jianwei Yang, Jun Zhao, Yuxian Bai, Xiangyuan Wu, Feng Gao, Guogui Sun, Yongjuan Wu, Feng Ye, Qiong Wang, Zhong Xie, Tienan Yi, Yong Huang, Guohua Yu, Lin Lu, Ying Yuan, Wei Li, Likun Liu, Yuping Sun, Ying Sun, Lifeng Yin, Zhiguo Hou
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Apatinib, a highly selective VEGFR2 inhibitor, significantly improved efficacy versus placebo as a third- and later-line treatment for advanced gastric cancer in phase 2 and 3 trials. This prospective, single-arm, multicenter phas
Externí odkaz:
https://doaj.org/article/8f346a3b7ad5448abb9d1f638b99755a
Autor:
Yishuang Cui, Yanan Wu, Mengshi Zhang, Yingze Zhu, Xin Su, Wenyue Kong, Xuan Zheng, Guogui Sun
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveTo discern long non-coding RNAs (lncRNAs) with prognostic relevance in the context of lung squamous cell carcinoma (LUSC), we intend to predict target genes by leveraging The Cancer Genome Atlas (TCGA) repository. Subsequently, we aim to inv
Externí odkaz:
https://doaj.org/article/a316420940434e8c837d5b40295632a9
Autor:
Chao Zeng, Wei Zhang, Meiyue Liu, Jianping Liu, Qiangxin Zheng, Jianing Li, Zhiwu Wang, Guogui Sun
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveThis study aimed to establish a predictive model for occult lymph node metastasis (LNM) in patients with clinical stage I-A non-small cell lung cancer (NSCLC) based on contrast-enhanced CT.MethodsA total of 598 patients with stage I–IIA NS
Externí odkaz:
https://doaj.org/article/f23f98fb6c2b4f8ebcd08371dd73c85f
Autor:
Baoen Shan, Cong Zhang, Guogui Sun, Hongtao Zhang, Xiaoya Li, Sisi Wei, Suli Dai, Huixia Wang, Lianmei Zhao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Tumor-associated macrophages (TAMs) are a major component of the tumor microenvironment (TME) and exert an important role in tumor progression. Due to the heterogeneity and plasticity of TAMs, modulating the polarization states of TAMs is
Externí odkaz:
https://doaj.org/article/2de85bce8d3e4dd988a530b2d1ad51f8
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is one of the most prevalent, fatal, and highly heterogeneous diseases that, seriously threaten human health. Lung cancer is primarily caused by the aberrant expression of multiple genes in the cells. Lung cancer treatment options include
Externí odkaz:
https://doaj.org/article/8228ebe413914e80ae3d308f1b1e5ecc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Emerging evidence indicates that the cellular electromagnetic field regulates the fundamental physics of cell biology. The electromagnetic oscillations and synchronization of biomolecules triggered by the internal and external pulses serve as the phy
Externí odkaz:
https://doaj.org/article/5bffb14d9aa343b7af4568070643c378
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Background Increased reactive oxygen species (ROS) production by arsenic treatment in solid tumors showed to be effective to sensitize cancer cells to chemotherapies. Arsenic nano compounds are known to increase the ROS production in solid t
Externí odkaz:
https://doaj.org/article/22e66394ac5d404fa4ff44a9615dff54
Autor:
Jiarui Yu, Siyuan Chen, Yi Niu, Meiyue Liu, Jie Zhang, Zhao Yang, Peng Gao, Wei Wang, Xiaochen Han, Guogui Sun
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 315-331 (2020)
Novel therapies tailored to the molecular composition mechanism of esophageal squamous cell carcinoma (ESCC) are needed to improve patient survival. miR-20b-5p expression was significantly upregulated in cancerous tissues and associated with lymph no
Externí odkaz:
https://doaj.org/article/4d9a2895d23b48c4825e09c3eb176eef