Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state

Autor: Erin Neyhart, Na Zhou, Brandon R. Munn, Robert G. Law, Cameron Smith, Zakir H. Mridha, Francisco A. Blanco, Guochuan Li, Yulong Li, Ming Hu, Matthew J. McGinley, James M. Shine, Jacob Reimer

Publikováno v: Cell Reports, Vol 43, Iss 10, Pp 114808- (2024)

Summary: Acetylcholine (ACh) is thought to play a role in driving the rapid, spontaneous brain-state transitions that occur during wakefulness; however, the spatiotemporal properties of cortical ACh activity during these state changes are still uncle

Externí odkaz: https://doaj.org/article/71236ae5ac384762ada080f0663a773f

Early-phase insulin hypersecretion associated with weight loss outcome after LSG: a prospective cohort study in Asian patients with BMI ≥28 kg/m2

Autor: Lu Guo, Wenjin Luo, Tao Tan, Faping Gong, Xiurong Liu, Siqi Rao, Fei Lian, Jia Liu, Xiangjun Chen, Guochuan Li, Zhiyou Yang, Mei Mei, Jinbo Hu, Qifu Li, Zhihong Wang, Jun Zhang, Menghua Zeng, Lilin Gong

Publikováno v: Surgery for Obesity and Related Diseases. 18:1209-1217

Obesity has become a global problem that poses a serious threat to human health. Laparoscopic sleeve gastrectomy (LSG) is an effective long-term treatment. However, the weight loss of some patients after LSG is still insufficient. It is necessary to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64c86654e85755e8ff5474ce163a0ba
https://doi.org/10.1016/j.soard.2022.05.013

Genetically encoded sensors for measuring histamine release both in vitro and in vivo

Autor: Hui Dong, Mengyao Li, Yuqi Yan, Tongrui Qian, Yunzhi Lin, Xiaoyuan Ma, Henry F. Vischer, Can Liu, Guochuan Li, Huan Wang, Rob Leurs, Yulong Li

Publikováno v: Dong, H, Li, M, Yan, Y, Qian, T, Lin, Y, Ma, X, Vischer, H F, Liu, C, Li, G, Wang, H, Leurs, R & Li, Y 2023, ' Genetically encoded sensors for measuring histamine release both in vitro and in vivo ', Neuron, vol. 111, no. 10, pp. 1564-1576.e6 . https://doi.org/10.1016/j.neuron.2023.02.024
Neuron, 111(10), 1564-1576.e6. Cell Press

Histamine (HA) is a key biogenic monoamine involved in a wide range of physiological and pathological processes in both the central and peripheral nervous systems. Because the ability to directly measure extracellular HA in real time will provide imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3193df0223bda9f2bd75a296143d8542
https://doi.org/10.1016/j.neuron.2023.02.024