Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Guobo Shen"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Adoptive cell therapy has revolutionized cancer treatment, especially for hematologic malignancies. T cells are the most extensively utilized cells in adoptive cell therapy. Currently, tumor-infiltrating lymphocytes, T cell receptor-transgen
Externí odkaz:
https://doaj.org/article/51082d0ada2a4917bf751e2cf40b8999
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-50 (2024)
Abstract Inflammation-associated diseases encompass a range of infectious diseases and non-infectious inflammatory diseases, which continuously pose one of the most serious threats to human health, attributed to factors such as the emergence of new p
Externí odkaz:
https://doaj.org/article/0082ecaad6a2450e8cc8f92ea7573981
Autor:
Weiqi Hong, Hong Lei, Dandan Peng, Yuhe Huang, Cai He, Jingyun Yang, Yanan Zhou, Jian Liu, Xiangyu Pan, Haiying Que, Aqu Alu, Li Chen, Jiayuan Ai, Furong Qin, Binhan Wang, Danyi Ao, Zhen Zeng, Ying Hao, Yu Zhang, Xiya Huang, Chunjun Ye, MinYang Fu, Xuemei He, Zhenfei Bi, Xuejiao Han, Min Luo, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Lu Chen, Xikun Zhou, Wei Wang, Guangwen Lu, Guobo Shen, Li Yang, Jinliang Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Qiangming Sun, Shuaiyao Lu, Youchun Wang, Ping Cheng, Xiawei Wei
Publikováno v:
MedComm, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Urgent research into innovative severe acute respiratory coronavirus‐2 (SARS‐CoV‐2) vaccines that may successfully prevent various emerging emerged variants, particularly the Omicron variant and its subvariants, is necessary. Here, we
Externí odkaz:
https://doaj.org/article/5f86cf25f441434681a4705fbc53e5ee
Publikováno v:
MedComm – Oncology, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Synthetic lethality (SL), a genetic concept, has revolutionized the development of antitumor therapies by providing avenues to target previously “undruggable” targets with enhanced specificity for tumor cells over normal tissue. The prin
Externí odkaz:
https://doaj.org/article/d2fe79e35ee747f98e85a55ae349c464
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Recent progressions in immunotherapy have transformed cancer treatment, providing a promising strategy that activates the immune system of the patient to find and eliminate cancerous cells. Bispecific antibodies, which engage two separate antigens or
Externí odkaz:
https://doaj.org/article/47bf929bc78c4aa3aa49fcfd8ca85f71
Autor:
Jingyun Yang, Weiqi Hong, Hong Lei, Cai He, Wenwen Lei, Yanan Zhou, Tingmei Zhao, Aqu Alu, Xuelei Ma, Jiong Li, Li Yang, Zhenling Wang, Wei Wang, Guangwen Lu, Guobo Shen, Shuaiyao Lu, Guizhen Wu, Huashan Shi, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract The COVID-19 response strategies in Chinese mainland were recently adjusted due to the reduced pathogenicity and enhanced infectivity of Omicron subvariants. In Chengdu, China, an infection wave was predominantly induced by the BA.5 subvaria
Externí odkaz:
https://doaj.org/article/8aab6045978541f78f42a3cf5965ed05
Autor:
Cai He, Li Chen, Jingyun Yang, Zimin Chen, Hong Lei, Weiqi Hong, Xiangrong Song, Li Yang, Jiong Li, Wei Wang, Guobo Shen, Guangwen Lu, Xiawei Wei
Publikováno v:
Molecular Biomedicine, Vol 4, Iss 1, Pp 1-13 (2023)
Abstract The current Coronavirus Disease 2019 (COVID-19) pandemic, induced by newly emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants, posed great threats to global public health security. There is an urgent need
Externí odkaz:
https://doaj.org/article/12a713a8db804a0081593b373ca0cf54
Autor:
Kui Wang, Li Luo, Shuyue Fu, Mao Wang, Zihao Wang, Lixia Dong, Xingyun Wu, Lunzhi Dai, Yong Peng, Guobo Shen, Hai-Ning Chen, Edouard Collins Nice, Xiawei Wei, Canhua Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The role of protein arginine methylation in serine metabolism of cancer cells in hepatocellular carcinoma (HCC) remains to be explored. Here, the authors show that phosphoglycerate dehydrogenase (PHGDH) is activated by PRMT1-mediated R236 methylation
Externí odkaz:
https://doaj.org/article/a8cf977e10a64602a434646123cf3d01
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-38 (2023)
Abstract Recent advances in neoantigen research have accelerated the development and regulatory approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and antibody-based therapies, especially for solid tumors. Neoantigens
Externí odkaz:
https://doaj.org/article/f07a894243d5416dab33c79477e8c8cc
Autor:
Cai He, Aqu Alu, Hong Lei, Jingyun Yang, Weiqi Hong, Xiangrong Song, Jiong Li, Li Yang, Wei Wang, Guobo Shen, Guangwen Lu, Xiawei Wei
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract The XBB.1.5 subvariant has drawn great attention owing to its exceptionality in immune evasion and transmissibility. Therefore, it is essential to develop a universally protective coronavirus disease 2019 vaccine against various strains of O
Externí odkaz:
https://doaj.org/article/4516bdfab07e4c0b9dcf39d0d532b923