Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Guobei Yan"'
Publikováno v:
RSC Advances. 9:36649-36657
Atherosclerosis is a chronic progressive cardiovascular disease, which may result in many clinical consequences. Ubiquitin-specific protease 14 (USP14), a member of the USP family, has been found to be involved in cardiovascular disease. In the prese
Autor:
Jun Tian, Wenchao Liu, Suping Li, Hong Wang, Guobei Yan, Kai Li, Junhua Wang, N A Liu, Hongbin Liu, Xiaoliang Li
Publikováno v:
Journal of biosciences. 46
The ubiquitin–proteasome system is an essential regulator of Acf7, which serves as a key effector for the maintenance of the EMT program and migration. However, the precise mechanism for the deubiquitination of Acf7 is still not fully understood. U
Autor:
Jingjing Zou, Yanli Fu, Qing Wang, Kai Li, Guobei Yan, Suping Li, Wei Wei, Junhua Wang, Na Liu, Jun Tian
Publikováno v:
Journal of Cellular and Molecular Medicine
The ubiquitin‐proteasome system is an essential regulator of ARMC5, which serves as a new tumour suppressor protein for inhibiting meningiomas and hereditary adrenocortical tumorigenesis. However, the precise mechanism for the deubiquitination of A
Autor:
Yang Sun, Xin Song, Zhen Li, Weihong Tan, Jianglin Li, Mao Ye, Jun Hu, Xiaoxiao Hu, Tanggang Deng, Peifu Feng, Dong Wei, Lin Xie, Jing Liu, Guobei Yan, Yu Zhou, Bin Hu, Yibin Zhang, Hui Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Previous studies have demonstrated that p21 occupies a central position in cell-cycle regulation and DNA damage responses. As an unstable protein, the regulation of p21 stability has been extensively investigated over the past 20 years.
Autor:
Lili Zhang, Zilong Zhao, Weihong Tan, Xiaoxiao Hu, Xiao-Bing Zhang, Huarong Bai, Xiaoyi Fu, Huanhuan Fan, Li-Hui Liang, Guobei Yan
Publikováno v:
Chemical Communications. 54:4310-4313
Herein, we developed a strategy to attack the cancer cell defense system against reactive oxygen species to improve photodynamic therapy efficacy with a Ce6@MSN@MTH1 siRNA nanosystem, which was demonstrated to improve cellular sensitivity to reactive
Autor:
Huanhuan Fan, Guobei Yan, Zilong Zhao, Xiaoxiao Hu, Wenhan Zhang, Hui Liu, Xiaoyi Fu, Ting Fu, Xiao‐Bing Zhang, Weihong Tan
Publikováno v:
Angewandte Chemie. 128:5567-5572
Autor:
Wenhan Zhang, Xiao-Bing Zhang, Ting Fu, Xiaoxiao Hu, Xiaoyi Fu, Weihong Tan, Zilong Zhao, Hui Liu, Huanhuan Fan, Guobei Yan
Publikováno v:
Angewandte Chemie International Edition. 55:5477-5482
Photodynamic therapy (PDT) has been applied in cancer treatment by utilizing reactive oxygen species to kill cancer cells. However, a high concentration of glutathione (GSH) is present in cancer cells and can consume reactive oxygen species. To addre
Autor:
Cai Yang, Yang Sun, Minlan Duan, Chao Yang, Xin Song, Jianglin Li, Xiaoxiao Hu, Weihong Tan, Jieying Chen, Zhen Li, Jing Liu, Kuangpei Wu, Guobei Yan, Mao Ye
Publikováno v:
Journal of Cellular and Molecular Medicine
WD‐repeat protein 79 (WDR79), a member of the WD‐repeat protein family, acts as a scaffold protein, participating in telomerase assembly, Cajal body formation and DNA double‐strand break repair. Here, we first report that WDR79 is frequently ov
Autor:
Mao Ye, Cheng Cui, Cheng Jin, Ruowen Wang, Weihong Tan, Liping Qiu, Danqing Lu, Hao Liang, Guobei Yan, Rongshan Chang, Huarong Bai
Publikováno v:
Chemical Science. 7:2157-2161
Conjugation of DNA to defined locations on a protein surface will be a powerful tool for positioning functional groups and molecules in biological and biomedical studies. However, tagging protein with DNA is challenging in physiological environments,
Autor:
Yani Tang, Zhen Li, Mao Ye, Huarong Bai, Tanggang Deng, Chao Yang, Kuangpei Wu, Yang Sun, Xiaoxiao Hu, Weihong Tan, Jing Liu, Xin Song, Hui Li, Guobei Yan, Cai Yang
Publikováno v:
Journal of Cellular and Molecular Medicine
Sip1/tuftelin‐interacting protein (STIP), a multidomain nuclear protein, is a novel factor associated with the spliceosome, yet its role and molecular function in cancer remain unknown. In this study, we show, for the first time, that STIP is overe