Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Guoan Chen"'
Autor:
Huijie Zhao, Xing Wu, Yinghan Wang, Xiuling Li, Yuhui Du, Zhiqing Zhou, Yu Li, Yue Liu, Xiaofei Zeng, Guoan Chen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background A growing body of evidence indicates that histone variants play an oncogenic role in cancer progression. However, the role and mechanism of histone variant H2AZ1 in lung cancer remain poorly understood. In this study, we aim to id
Externí odkaz:
https://doaj.org/article/8139edbb24c140fa897346c9631bc652
Autor:
Zhiqing Zhou, Yu Li, Sijie Chen, Zhangrong Xie, Yuhui Du, Yue Liu, Yuxuan Shi, Xiangyi Lin, Xiaofei Zeng, Huijie Zhao, Guoan Chen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background While previous studies have primarily focused on Glucose transporter type 1 (GLUT1) related glucose metabolism signaling, we aim to discover if GLUT1 promotes tumor progression through a non-metabolic pathway. Methods The RNA-seq
Externí odkaz:
https://doaj.org/article/d46beaf3778d4fe7928e3c9eb3bbea34
Autor:
Jiancong Wu, Xiaobi Huang, Xiaofang Li, Honglian Zhou, Xiaorao Chen, Yongyang Chen, Yudong Guo, Jian Huang, Hanqing Huang, Zhong Huang, Guoan Chen, Zhixiong Yang, Jian Zhang, Wenmei Su
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Long non-coding RNAs play critical roles in the development of lung cancer by functioning as tumor suppressors or oncogenes. Changes in the expression of LINC01279 have been associated with cell differentiation and human diseases. However, t
Externí odkaz:
https://doaj.org/article/be21cb37839347e5944177df7c4fdac2
Autor:
Yan Qin, Yongping Song, Dong Wang, Ou Bai, Jifeng Feng, Xiuhua Sun, Lihua Qiu, Jianmin Yang, Yu Yang, Zhao Wang, Jianda Hu, Huaqing Wang, Hang Su, Zhengming Jin, Wenbin Qian, Chuan Jin, Mingzhi Zhang, Ding Yu, Li Liu, Guoan Chen, Yarong Li, Tao Sun, Jie Jin, Huizheng Bao, Xin Du, Hui Zhou, Gan Fu, Yuankai Shi
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract HLX01 (HanliKang®) is a rituximab biosimilar that showed bioequivalence to reference rituximab in untreated CD20-positive diffuse large B-cell lymphoma (DLBCL) in the phase 3 HLX01-NHL03 study. Here, we report the 5-year follow-up results f
Externí odkaz:
https://doaj.org/article/7eecafad55844bb3b801aa99db2e8a55
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Regulated cell death (RCD) is a regulable cell death that involves well-organized signaling cascades and molecular mechanisms. RCD is implicated in fundamental processes such as organ production and tissue remodeling, removing superfluous st
Externí odkaz:
https://doaj.org/article/9477ad102c8f46b9a9075166f4d9f4eb
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0b5db83b57e8477e96381e84b19d84e4
Autor:
Yan Chen, Ruibin Huang, Jianghua Ding, Dexiang Ji, Bing Song, Liya Yuan, Hong Chang, Guoan Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/9f0f85c5efca4e51ae3972f48eea6450
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Single-cell sequencing is a technique for detecting and analyzing genomes, transcriptomes, and epigenomes at the single-cell level, which can detect cellular heterogeneity lost in conventional sequencing hybrid samples, and it has revolutionized our
Externí odkaz:
https://doaj.org/article/128065cde5774c28bff9b36d4812f6e0
Autor:
Jiefeng Gan, Hanchen Wang, Hui Yu, Zitong He, Wenjuan Zhang, Ke Ma, Lianghui Zhu, Yutong Bai, Zongwei Zhou, Alan Yullie, Xiang Bai, Mingwei Wang, Dehua Yang, Yanyan Chen, Guoan Chen, Joan Lasenby, Chao Cheng, Jia Wu, Jianjun Zhang, Xinggang Wang, Yaobing Chen, Guoping Wang, Tian Xia
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107243- (2023)
Summary: Image-based AI has thrived as a potentially revolutionary tool for predicting molecular biomarker statuses, which aids in categorizing patients for appropriate medical treatments. However, many methods using hematoxylin and eosin-stained (H&
Externí odkaz:
https://doaj.org/article/3f12fb5bf3c74cdaaa9360ca20103e46
Autor:
Ting Qiao, Wanli Yang, Xiangchuan He, Ping Song, Xiao Chen, Ruijie Liu, Jian Xiao, Xiaoli Yang, Mingqi Li, Yudan Gao, Guoan Chen, Yi Lu, Jian Zhang, Jing Leng, Huan Ren
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-11 (2023)
Abstract Tumor-associated macrophages (TAMs) are highly heterogeneous and play vital roles in tumor progression. Here we adopted a C57BL/6 mouse model imitating the late-stage colorectal liver metastasis (CRLM) by Mc38 colorectal cancer cell injectio
Externí odkaz:
https://doaj.org/article/200a476f79a5407c8728a1fa78768c35