Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Guo-tong Xu"'
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Human amniotic membrane (AM) transplantation has been applied to treat ocular surface diseases, including corneal trauma. The focus of much deliberation is to balance the mechanical strength of the amniotic membrane, its resistanc
Externí odkaz:
https://doaj.org/article/1123fd07528948b2b350971e7bcaf861
Autor:
Dandan Liu, Jingxiao Du, Hai Xie, Haibin Tian, Lixia Lu, Chaoyang Zhang, Guo-Tong Xu, Jingfa Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Background Neovascular age-related macular degeneration (nAMD), accounts for up to 90% of AMD-associated vision loss, ultimately resulting in the formation of fibrotic scar in the macular region. The pathogenesis of subretinal fibrosis in nA
Externí odkaz:
https://doaj.org/article/fef78b1d131a4454bb8ae6e4b3f75d26
Autor:
Jinyuan Xu, Lilin Zhu, Jie Xu, Kailong Lin, Juan Wang, Yan-long Bi, Guo-Tong Xu, Haibin Tian, Furong Gao, Caixia Jin, Lixia Lu
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundTo identify key and shared insulin resistance (IR) molecular signatures across all insulin-sensitive tissues (ISTs), and their potential targeted drugs.MethodsThree datasets from Gene Expression Omnibus (GEO) were acquired, in which the IST
Externí odkaz:
https://doaj.org/article/e1d7257d7a184d85b45f585fea94bec7
Autor:
Dongli Li, Qingjian Ou, Qi Shen, Michael Mingze Lu, Jing-Ying Xu, Caixia Jin, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Jiao Li, Lixia Lu, Guo-Tong Xu, Haibin Tian
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background T helper 2 (Th2) cells are thought to play critical roles in allergic conjunctivitis (AC). They release inflammatory cytokines to promote an allergic response in AC. Due to individual heterogeneity and long-term chronic management
Externí odkaz:
https://doaj.org/article/610c53d3aaf94daa9ecdb872309f9d89
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106250- (2023)
Age-related macular degeneration (AMD) is a leading cause of vision loss among elderly people in developed countries. Neovascular AMD (nAMD) accounts for more than 90% of AMD-related vision loss. At present, intravitreal injection of anti-vascular en
Externí odkaz:
https://doaj.org/article/3884220975f04d6e88de14ce5de95d3b
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 7, Pp 1441-1449 (2023)
Epigenetics focuses on DNA methylation, histone modification, chromatin remodeling, noncoding RNAs, and other gene regulation mechanisms beyond the DNA sequence. In the past decade, epigenetic modifications have drawn more attention as they participa
Externí odkaz:
https://doaj.org/article/dc52c1cd982c4e24ae8076e449d1c4df
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 976-982 (2023)
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease, is the leading cause of visual impairment in diabetic patients. Many clinical features observed in diabetic retinopathy, such as capillary occlusion, acellular ca
Externí odkaz:
https://doaj.org/article/1406e2b3438e4b5eb55ee54c27abf848
Autor:
Xiaoman Zhu, Zhiyang Chen, Li Wang, Qingjian Ou, Zhong Feng, Honglei Xiao, Qi Shen, Yingao Li, Caixia Jin, Jing-Ying Xu, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Zhiguo Xu, Guo-Tong Xu, Lixia Lu, Haibin Tian
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-15 (2022)
Abstract Age-related macular degeneration (AMD) is a major vision-threatening disease. Although mesenchymal stem cells (MSCs) exhibit beneficial neural protective effects, their limited differentiation capacity in vivo attenuates their therapeutic fu
Externí odkaz:
https://doaj.org/article/7cb646f140fe4be3b5afd15f711dd5a9
Autor:
Hai-Feng Qin, Fan-Jun Shi, Chao-Yang Zhang, Da-Wei Luo, Shi-Yue Qin, Jing Wu, Hai Xie, Jing-Ting Zhang, Qing-Hua Qiu, Kun Liu, Guo-Tong Xu, Guo-Xu Xu, Jing-Fa Zhang
Publikováno v:
International Journal of Ophthalmology, Vol 15, Iss 8, Pp 1296-1304 (2022)
AIM: To investigate the anti-inflammatory effect of intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) in patients with macular edema secondary to retinal vein occlusion (RVO-ME). METHODS: Twenty-eight eyes from twenty-eigh
Externí odkaz:
https://doaj.org/article/74f24c93b01e4602b044bffd17807a2c
Autor:
Caixia Jin, Qingjian Ou, Jie Chen, Tao Wang, Jieping Zhang, Zhe Wang, Yuanyuan Wang, Haibin Tian, Jing-Ying Xu, Furong Gao, Juan Wang, Jiao Li, Lixia Lu, Guo-Tong Xu
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Purpose To explore the function and regulatory mechanism of IFITM3 in mouse neural retinal progenitor cells (mNRPCs), which was found to be very important not only in the development of the retina in embryos but also in NRPCs after birth. Me
Externí odkaz:
https://doaj.org/article/294ad930350444e587ed1339f2343c17