Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Guo-sheng Hu"'
Autor:
Shi-qiang Cao, Song-tao Xue, Wen-juan Li, Guo-sheng Hu, Zhi-gang Wu, Jian-cong Zheng, Shu-liang Zhang, Xiao Lin, Chun Chen, Wen Liu, Bin Zheng
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract The oncogenic role of circRNA in cancers including esophageal cancer (EC) has been well studied. However, whether and how circRNAs are involved in cancer cell metabolic processes remains largely unknown. Here, we reported that circRNA, circH
Externí odkaz:
https://doaj.org/article/3675f2c1579846d7ad01b8b1c1b2dcdb
Autor:
Wen-juan Li, Ying Huang, Yi-an Lin, Bao-ding Zhang, Mei-Yan Li, Yi-qin Zou, Guo-sheng Hu, Yao-hui He, Jing-jing Yang, Bing-lan Xie, Hai-hua Huang, Xianming Deng, Wen Liu
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113385- (2023)
Summary: PRMT1 plays a vital role in breast tumorigenesis; however, the underlying molecular mechanisms remain incompletely understood. Herein, we show that PRMT1 plays a critical role in RNA alternative splicing, with a preference for exon inclusion
Externí odkaz:
https://doaj.org/article/ade4efd1b9394bd298d24afc3ff21873
Autor:
Xue Chen, Jian‐cheng Ding, Guo‐sheng Hu, Xing‐yi Shu, Yan Liu, Jun Du, Zi‐jing Wen, Jun‐yi Liu, Hai‐hua Huang, Guo‐hui Tang, Wen Liu
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Endocrine therapy is the frontline treatment for estrogen receptor (ER) positive breast cancer patients. However, the primary and acquired resistance to endocrine therapy drugs remain as a major challenge in the clinic. Here, this work ident
Externí odkaz:
https://doaj.org/article/317ad364ca7344ad8330087003b2b461
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a common invasive malignancy worldwide with poor clinical outcomes. Increasing amount of long non-coding RNAs (lncRNAs) have been reported to be involved in cancer development. However,
Externí odkaz:
https://doaj.org/article/eb94c759891d4366865302fd59cc8a88
Autor:
Wen-juan Li, Yao-hui He, Jing-jing Yang, Guo-sheng Hu, Yi-an Lin, Ting Ran, Bing-ling Peng, Bing-lan Xie, Ming-feng Huang, Xiang Gao, Hai-hua Huang, Helen He Zhu, Feng Ye, Wen Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Arginine methyltransferases (PRMTs) are involved in the regulation of various physiological and pathological conditions. Using proteomics, the authors here profile the methylation substrates of PRMTs 4, 5 and 7 and characterize the roles of these enz
Externí odkaz:
https://doaj.org/article/8e1165b1d3b04a91a453caaef784fec5
Autor:
Hai‐feng Shen, Wen‐juan Zhang, Ying Huang, Yao‐hui He, Guo‐sheng Hu, Lei Wang, Bing‐ling Peng, Jia Yi, Ting‐ting Li, Rui Rong, Xiao‐yan Chen, Jun‐yi Liu, Wen‐juan Li, Kenny Ohgi, Shao‐Wei Li, Michael G. Rosenfeld, Wen Liu
Publikováno v:
Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)
Abstract Emerging evidence suggested that epigenetic regulators can exhibit both activator and repressor activities in gene transcriptional regulation and disease development, such as cancer. However, how these dual activities are regulated and coord
Externí odkaz:
https://doaj.org/article/ec880b50ff614bc8a1c441bf0a205ceb
Autor:
Wu, Zheng, Pan, Teng, Li, Wen, Zhang, Yue-hua, Guo, Sheng-hu, Liu, Ya, Zhang, Lei, Wang, Zhi-yu
Publikováno v:
Clinical & Translational Oncology; Oct2024, Vol. 26 Issue 10, p2701-2717, 17p
Publikováno v:
Clinical Cancer Research. 29:2095-2109
Purpose: The oncogenic role of circular RNAs (circRNA) has been well studied in cancers including colorectal cancer. However, tumor-suppressive circRNAs and the mechanism through which they exert their antitumor effects remain largely unknown. We aim
Autor:
Lin Xia, Lun-zhi Yuan, Ya-hong Hu, Jun-yi Liu, Guo-sheng Hu, Ruo-yao Qi, Tian-ying Zhang, Hua-long Xiong, Zao-zao Zheng, Hong-wei Lin, Jia-mo Zhang, Chao Yu, Ming Zhou, Jian Ma, Tong Cheng, Ri-rong Chen, Yi Guan, Ning-shao Xia, Wen Liu
Publikováno v:
Cellular & Molecular Immunology. 20:351-364
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective against inflammation to treat lethal COVID-19
Publikováno v:
IEEE Transactions on Information Theory. 68:5548-5560