Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Guo-qing LU"'
Autor:
Xin-yang Li, De-pu Wang, Guo-qing Lu, Kai-li Liu, Ting-jian Zhang, Shuai Li, Kamara Mohamed O, Wen-han Xue, Xin-hua Qian, Fan-hao Meng
Publikováno v:
Journal of Advanced Research, Vol 26, Iss , Pp 95-110 (2020)
Introduction: The development of a new type of Thymidylate synthase (TS) inhibitor that could inhibit cancer cells' proliferation and anti-angiogenesis is of great significance for cancer's clinical treatment. Objectives: Our research hopes to develo
Externí odkaz:
https://doaj.org/article/4f83fc20ee194913a0ab24d90932a074
Autor:
Yu-qiong HAO, Guo-qing LU, Li-hua WANG, Chun-ling WANG, Hui-ming GUO, Yi-fei LI, Hong-mei CHENG
Publikováno v:
Journal of Integrative Agriculture, Vol 17, Iss 10, Pp 2204-2214 (2018)
As abiotic stresses become more severe as a result of global climate changes, the growth and development of plants are restricted. In the development of agricultural crops with greater stress tolerance, AmDUF1517 had been isolated from the highly str
Externí odkaz:
https://doaj.org/article/0c0ff50c85584bc68f76ada875ed2b01
Publikováno v:
Tongxin xuebao, Vol 37, Pp 175-182 (2016)
A differential privacy algorithm DiffPRFs based on random forests was proposed.Exponential mechanism was used to select split point and split attribute in each decision tree building process,and noise was added according to Laplace mechanism.Differen
Externí odkaz:
https://doaj.org/article/f52cd151a8ba473b980930749adce422
Autor:
Li-ping DING, Guo-qing LU
Publikováno v:
Tongxin xuebao, Vol 35, Pp 200-209 (2014)
Frequent pattern mining is an exploratory problem in the field of data mining.However,directly releasing the discovered frequent patterns and the corresponding true supports may reveal the individuals’ privacy.The state-of-the-art solution for this
Externí odkaz:
https://doaj.org/article/53659fb7695e48de81ad2ac8ab233600
Publikováno v:
Acta Pharmacologica Sinica. 44:546-560
Sirtuin3 (SIRT3), a class III histone deacetylase, is implicated in various cardiovascular diseases as a novel therapeutic target. SIRT3 has been proven to be cardioprotective in a model of Ang II-induced cardiac hypertrophy. However, a few small-mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e17deb3fb8efa440533e5219e92749
https://doi.org/10.1038/s41401-022-00966-8
https://doi.org/10.1038/s41401-022-00966-8
Autor:
Wen-han Xue, Xin-yang Li, De-pu Wang, Kamara Mohamed O, Guo-qing Lu, Ting-jian Zhang, Fan-hao Meng, Shuai Li, Kai-li Liu, Xin-hua Qian
Publikováno v:
Journal of Advanced Research, Vol 26, Iss, Pp 95-110 (2020)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Introduction The development of a new type of Thymidylate synthase (TS) inhibitor that could inhibit cancer cells' proliferation and anti-angiogenesis is of great significance for cancer's clinical treatment. Objectives Our re
Introduction The development of a new type of Thymidylate synthase (TS) inhibitor that could inhibit cancer cells' proliferation and anti-angiogenesis is of great significance for cancer's clinical treatment. Objectives Our re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeb0fa79316d0e423b2cd592ca64c29
http://www.sciencedirect.com/science/article/pii/S2090123220301673
http://www.sciencedirect.com/science/article/pii/S2090123220301673
Autor:
Bo-Hao Liu, Chen-Zhen Xu, Yi Liu, Zi-Long Lu, Ting-Lv Fu, Guo-Rui Li, Yu Deng, Guo-Qing Luo, Song Ding, Ning Li, Qing Geng
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-59 (2024)
Abstract Mitochondria, the most crucial energy-generating organelles in eukaryotic cells, play a pivotal role in regulating energy metabolism. However, their significance extends beyond this, as they are also indispensable in vital life processes suc
Externí odkaz:
https://doaj.org/article/1c3b4e5347e3408ea967f48f3614277d
Autor:
De-pu Wang, Fan-hao Meng, Guo-qing Lu, Hai-li Xu, Xin-yang Li, Mohamed Olounfeh Kamara, Ting-jian Zhang
Publikováno v:
Cell Death and Disease, Vol 10, Iss 7, Pp 1-16 (2019)
Cell Death & Disease
Cell Death & Disease
Thymidylate synthase (TS) is a hot target for tumor chemotherapy, and its inhibitors are an essential direction for anti-tumor drug research. To our knowledge, currently, there are no reported thymidylate synthase inhibitors that could inhibit cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e036a7b6478be5b06599088816ff4f95
http://link.springer.com/article/10.1038/s41419-019-1773-0
http://link.springer.com/article/10.1038/s41419-019-1773-0
Autor:
Yi-fei Li, Li-hua Wang, Chun-ling Wang, Huiming Guo, Hong-mei Cheng, Guo-qing Lu, Yuqiong Hao
Publikováno v:
Journal of Integrative Agriculture, Vol 17, Iss 10, Pp 2204-2214 (2018)
As abiotic stresses become more severe as a result of global climate changes, the growth and development of plants are restricted. In the development of agricultural crops with greater stress tolerance, AmDUF1517 had been isolated from the highly str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a01a385d1fd6ba74fc8e5a117bd1efa
https://doi.org/10.1016/s2095-3119(17)61897-5
https://doi.org/10.1016/s2095-3119(17)61897-5
Publikováno v:
European Journal of Medicinal Chemistry. 154:267-279
The Inhibition of cellular nucleotide metabolism to promote apoptosis is a key principle of cancer therapy. Thymidylate synthase (TS) is a key rate-limiting enzyme in the initiation of DNA synthesis in cell. Here, we presented two types of thymidylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6809dbf5b1345e4c3c295218eab7567
https://doi.org/10.1016/j.ejmech.2018.05.020
https://doi.org/10.1016/j.ejmech.2018.05.020