Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Guo-Yuan Hu"'
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e1000938 (2010)
Although the potent anti-parkinsonian action of the atypical D₁-like receptor agonist SKF83959 has been attributed to the selective activation of phosphoinositol(PI)-linked D₁ receptor, whereas the mechanism underlying its potent neuroprotective
Externí odkaz:
https://doaj.org/article/1f84b0b05e0844f9b9ca019d9e3bbc87
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5811 (2009)
(+/-) SKF83959, like many other arylbenzazepines, elicits powerful neuroprotection in vitro and in vivo. The neuroprotective action of the compound was found to partially depend on its D(1)-like dopamine receptor agonistic activity. The precise mecha
Externí odkaz:
https://doaj.org/article/7508d982aa0449b3b4b8a817edb57a18
Publikováno v:
Acta Pharmacologica Sinica. 31:665-670
To examine the involvement of K(+) channels and endothelium in the vascular effects of magnesium lithospermate B (MLB), a hydrophilic active component of Salviae miltiorrhiza Radix.Isolated rat mesenteric artery rings were employed to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae42ba63e9414330db299ae1e7bfb762
https://doi.org/10.1038/aps.2010.40
https://doi.org/10.1038/aps.2010.40
Publikováno v:
Precision Engineering. 33:202-208
A novel hybrid measuring instrument, developed for the characterization of engineering surface, is presented. This instrument is capable of contact and non-contact measurement, and both measurement systems are based on a Linnik interference microscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc26197b12d2f4953ff76870976932b
https://doi.org/10.1016/j.precisioneng.2008.06.002
https://doi.org/10.1016/j.precisioneng.2008.06.002
Publikováno v:
Neuroscience. 155:469-475
Blocking specific K+ channels has been proposed as a promising strategy for the treatment of neurodegenerative diseases. Using a computational virtual screening approach and electrophysiological testing, we found four Aconitum alkaloids are potent bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb8e6aef92c290b399216379b0c3124
https://doi.org/10.1016/j.neuroscience.2008.06.009
https://doi.org/10.1016/j.neuroscience.2008.06.009
Publikováno v:
Acta Pharmacologica Sinica. 29:405-412
Aim: N,N′ -[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)] bis (4-methyl)-benzenesulfonamide (OMBSA) is a hit compound with potent voltage-gated K + (Kv) channel-blocking activities that was found while searching the MDL Available Chemicals Directory wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d9d198aa6829291af81a1f1787dd58
https://doi.org/10.1111/j.1745-7254.2008.00777.x
https://doi.org/10.1111/j.1745-7254.2008.00777.x
Publikováno v:
Tetrahedron. 64:2027-2034
Four unusually fused polycyclic sesquiterpenoid dimers, chlorahololides C–F (1–4), were isolated from the whole plant of Chloranthus holostegius. Their structures and absolute configurations were established by spectroscopic methods, including 2D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f7f21a62051ec7e14877ee5e8f8498b
https://doi.org/10.1016/j.tet.2007.12.057
https://doi.org/10.1016/j.tet.2007.12.057
Publikováno v:
Key Engineering Materials. :371-376
We have constructed a novel contact stylus profilometer which is, in a certain sense, a combination of a lever system, an x-y stage, a vertical scanning stage and a Linnik microscope interferometer with a spatially and temporally incoherent light sou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04fe5d846941bd2206287afaad6daa98
https://doi.org/10.4028/www.scientific.net/kem.364-366.371
https://doi.org/10.4028/www.scientific.net/kem.364-366.371
Publikováno v:
Brain Research. 1111:41-47
The red wine polyphenol trans-resveratrol has been found to exert potent protective actions in a variety of cerebral ischemia models. The neuroprotection by trans-resveratrol thus far is mainly attributed to its intrinsic antioxidant properties. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d37d56bab0986a4a1e15f1efee387b
https://doi.org/10.1016/j.brainres.2006.06.096
https://doi.org/10.1016/j.brainres.2006.06.096
Autor:
Bo Yu, Guo-Yuan Hu
Publikováno v:
European Journal of Pharmacology. 508:15-21
Donepezil (E2020) is a novel cholinesterase inhibitor for the treatment of Alzheimer's disease. Recent studies show that it may act on targets other than acetylcholinesterase in the brain. In the present study, the actions of donepezil on voltage-gat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2edd44ff2e88c5a1b1de5ea7b9fbdd4
https://doi.org/10.1016/j.ejphar.2004.12.004
https://doi.org/10.1016/j.ejphar.2004.12.004