Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Guo-Ping Zhou"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5682-5700 (2024)
It is known that sialyllactose (SL) in mammalians is a major source of sialic acid (Sia), which can further form cytidine monophosphate sialic acid (CMP-Sia), and the final product is polysialic acid (polySia) using polysialyltransferases (polySTs) o
Externí odkaz:
https://doaj.org/article/7e40d248d5b8495d87624f27c7373114
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Background Systemic lupus erythematosus (SLE) is a common autoimmune disease that impacts various organs. Lupus nephritis (LN) significantly contributes to death in children with SLE. Toll-like receptor (TLR) adaptor interacting with SLC15A4
Externí odkaz:
https://doaj.org/article/265777b919124393bd7404701f0223bf
Autor:
Bo Lu, Si-Ming Liao, Xue-Hui Liu, Shi-Jie Liang, Jun Huang, Mei Lin, Li Meng, Qing-Yan Wang, Ri-Bo Huang, Guo-Ping Zhou
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The overexpression of polysialic acid (polySia) on neural cell adhesion molecules (NCAM) promotes hypersialylation, and thus benefits cancer cell migration and invasion. It has been proposed that the binding between the polysialyltransferase domain (
Externí odkaz:
https://doaj.org/article/3ee323e26107490d828325cb76b0b536
Publikováno v:
Cancer Medicine, Vol 11, Iss 3, Pp 864-879 (2022)
Abstract Evidence has been emerging of the importance of long non‐coding RNAs (lncRNAs) in genome instability. However, no study has established how to classify such lncRNAs linked to genomic instability, and whether that connection poses a therape
Externí odkaz:
https://doaj.org/article/f756180eea4f4dc88582f9f1c8ad1cfe
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Cell pyroptosis is one of the main forms of neuronal injury after cerebral ischemia–reperfusion. It is accompanied by an inflammatory reaction and regulated by the caspase gene family. Electroacupuncture (EA) can reduce neuronal injury caused by ce
Externí odkaz:
https://doaj.org/article/3763c1b1b53041f89ee37434d99cc1ea
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Osteosarcoma is a quickly developing, malignant cancer of the bone, which is associated with a bad prognosis. In osteosarcoma, hypoxia promotes the malignant phenotype, which results in a cascade of immunosuppressive processes, poor prognosis, and a
Externí odkaz:
https://doaj.org/article/6b12d65ebba44d999143c0e08791d362
Autor:
Chun-Xiao Wu, Yi-Hui Feng, Lu Yang, Zhu-Lian Zhan, Xiu-Hong Xu, Xiao-Ying Hu, Zhi-Hua Zhu, Guo-Ping Zhou
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 9, Pp 1594-1601 (2018)
Simple regulation of c-Jun N-terminal kinase (JNK) or p38 mitogen-activated protein kinase (MAPK) pathways is not enough to trigger cell apoptosis. However, activation of the stress activated pathway (JNK/p38 MAPK) together with inhibition of the gro
Externí odkaz:
https://doaj.org/article/598eee9eb3c84b5c96de234502036c03
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Stimulator of Interferon Gene (STING) is a key mediator of innate immune signaling. STING plays a pivotal role in the pathogenesis of many diseases including infectious diseases, auto-immune diseases and cancer. Many studies have been carrie
Externí odkaz:
https://doaj.org/article/9217eb2fd9ec45ef8ee24e0b91145b09
Autor:
Lu-Lu Wang, Zheng-Sen Chen, Wen-Di Zhou, Jin Shu, Xiao-Hua Wang, Rui Jin, Li-Li Zhuang, Mir Alireza Hoda, Hao Zhang, Guo-Ping Zhou
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Interferon regulatory factor 3 (IRF-3) is widely known for its prompt response against viral infection by activating the interferon system. We previously reported that E2F1, Sp1 and Sp3 regulated transcriptional activity of IRF-3. Recently,
Externí odkaz:
https://doaj.org/article/78772c5eb2534f93aca2ace855ee5bab
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 3, Pp 409-416 (2017)
Electroacupuncture attenuates cerebral hypoxia and neuronal apoptosis induced by cerebral ischemia/reperfusion injury. To further identify the involved mechanisms, we assumed that electroacupuncture used to treat cerebral ischemia/reperfusion injury
Externí odkaz:
https://doaj.org/article/51619b053f0a47c09c2918595c9667aa