Zobrazeno 1 - 10 of 316 pro vyhledávání: '"Guo-Ping Zhou"'
1
Akademický článek
NMR Studies of the Interactions between Sialyllactoses and the Polysialytransferase Domain for Polysialylation Inhibition
Autor: Bo Lu, Si-Ming Liao, Shi-Jie Liang, Jian-Xiu Li, Xue-Hui Liu, Ri-Bo Huang, Guo-Ping Zhou
Publikováno v: Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5682-5700 (2024)
It is known that sialyllactose (SL) in mammalians is a major source of sialic acid (Sia), which can further form cytidine monophosphate sialic acid (CMP-Sia), and the final product is polysialic acid (polySia) using polysialyltransferases (polySTs) o
Externí odkaz: https://doaj.org/article/7e40d248d5b8495d87624f27c7373114
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2
Akademický článek
Inhibition of STAT3 alleviates LPS-induced apoptosis and inflammation in renal tubular epithelial cells by transcriptionally down-regulating TASL
Autor: Jin-Wen Xu, Ming-Yan Wang, Yan Mao, Zheng-Yun Hu, Xiao-Lin Miao, Feng Jiang, Guo-Ping Zhou
Publikováno v: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-14 (2024)
Abstract Background Systemic lupus erythematosus (SLE) is a common autoimmune disease that impacts various organs. Lupus nephritis (LN) significantly contributes to death in children with SLE. Toll-like receptor (TLR) adaptor interacting with SLC15A4
Externí odkaz: https://doaj.org/article/265777b919124393bd7404701f0223bf
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3
Akademický článek
The NMR studies of CMP inhibition of polysialylation
Autor: Bo Lu, Si-Ming Liao, Xue-Hui Liu, Shi-Jie Liang, Jun Huang, Mei Lin, Li Meng, Qing-Yan Wang, Ri-Bo Huang, Guo-Ping Zhou
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The overexpression of polysialic acid (polySia) on neural cell adhesion molecules (NCAM) promotes hypersialylation, and thus benefits cancer cell migration and invasion. It has been proposed that the binding between the polysialyltransferase domain (
Externí odkaz: https://doaj.org/article/3ee323e26107490d828325cb76b0b536
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5
Akademický článek
Computational detection of a genome instability‐derived lncRNA signature for predicting the clinical outcome of lung adenocarcinoma
Autor: Chen‐Rui Guo, Yan Mao, Feng Jiang, Chen‐Xia Juan, Guo‐Ping Zhou, Ning Li
Publikováno v: Cancer Medicine, Vol 11, Iss 3, Pp 864-879 (2022)
Abstract Evidence has been emerging of the importance of long non‐coding RNAs (lncRNAs) in genome instability. However, no study has established how to classify such lncRNAs linked to genomic instability, and whether that connection poses a therape
Externí odkaz: https://doaj.org/article/f756180eea4f4dc88582f9f1c8ad1cfe
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6
Akademický článek
Mechanism of Electroacupuncture Against Cerebral Ischemia–Reperfusion Injury: Reducing Inflammatory Response and Cell Pyroptosis by Inhibiting NLRP3 and Caspase-1
Autor: Li Cai, Zeng-Yu Yao, Lu Yang, Xiu-Hong Xu, Meng Luo, Miao-Miao Dong, Guo-Ping Zhou
Publikováno v: Frontiers in Molecular Neuroscience, Vol 15 (2022)
Cell pyroptosis is one of the main forms of neuronal injury after cerebral ischemia–reperfusion. It is accompanied by an inflammatory reaction and regulated by the caspase gene family. Electroacupuncture (EA) can reduce neuronal injury caused by ce
Externí odkaz: https://doaj.org/article/3763c1b1b53041f89ee37434d99cc1ea
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7
Akademický článek
A Hypoxia Gene-Based Signature to Predict the Survival and Affect the Tumor Immune Microenvironment of Osteosarcoma in Children
Autor: Feng Jiang, Xiao-Lin Miao, Xiao-Tian Zhang, Feng Yan, Yan Mao, Chu-Yan Wu, Guo-Ping Zhou
Publikováno v: Journal of Immunology Research, Vol 2021 (2021)
Osteosarcoma is a quickly developing, malignant cancer of the bone, which is associated with a bad prognosis. In osteosarcoma, hypoxia promotes the malignant phenotype, which results in a cascade of immunosuppressive processes, poor prognosis, and a
Externí odkaz: https://doaj.org/article/6b12d65ebba44d999143c0e08791d362
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9
Akademický článek
Electroacupuncture exerts neuroprotective effects on ischemia/reperfusion injury in JNK knockout mice: the underlying mechanism
Autor: Chun-Xiao Wu, Yi-Hui Feng, Lu Yang, Zhu-Lian Zhan, Xiu-Hong Xu, Xiao-Ying Hu, Zhi-Hua Zhu, Guo-Ping Zhou
Publikováno v: Neural Regeneration Research, Vol 13, Iss 9, Pp 1594-1601 (2018)
Simple regulation of c-Jun N-terminal kinase (JNK) or p38 mitogen-activated protein kinase (MAPK) pathways is not enough to trigger cell apoptosis. However, activation of the stress activated pathway (JNK/p38 MAPK) together with inhibition of the gro
Externí odkaz: https://doaj.org/article/598eee9eb3c84b5c96de234502036c03
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