Zobrazeno 1 - 10
of 349
pro vyhledávání: '"Guo-Ping Shi"'
Autor:
Xinrong Hu, Lu Gan, Ziwen Tang, Ruoni Lin, Zhou Liang, Feng Li, Changjian Zhu, Xu Han, Ruilin Zheng, Jiani Shen, Jing Yu, Ning Luo, Wenxing Peng, Jiaqing Tan, Xiaoyan Li, Jinjin Fan, Qiong Wen, Xin Wang, Jianbo Li, Xunhua Zheng, Qinghua Liu, Jianping Guo, Guo‐Ping Shi, Haiping Mao, Wei Chen, Sheng Yin, Yi Zhou
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Kidney fibrosis is a common fate of chronic kidney diseases (CKDs), eventually leading to renal dysfunction. Yet, no effective treatment for this pathological process has been achieved. During the bioassay‐guided chemical investigation of
Externí odkaz:
https://doaj.org/article/054a6dfa8a9f4409ad41f1fd3edfd7f9
Publikováno v:
Cardiology Discovery, Vol 3, Iss 3, Pp 166-182 (2023)
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can lead to a cytokine storm, unleashed in part by pyroptosis of virus-infected macrophages and monocytes. Interleukin-6 (IL-6) has emerged as a key participant in this ominous co
Externí odkaz:
https://doaj.org/article/f750ec6171ec4a6a8173cbb7a11bb15d
Autor:
Huai‐Wen Chang, Hui Zhang, Guo‐Ping Shi, Jiang‐Hong Guo, Xue‐Feng Chu, Zheng‐Dong Wang, Yin Yao, Xiao‐Feng Wang
Publikováno v:
Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Objective Compared logistic regression (LR) with machine learning (ML) models, to predict the risk of ischemic stroke in an elderly population in China. Methods We applied 2208 records from the Rugao Longitudinal Ageing Study (RLAS) for isch
Externí odkaz:
https://doaj.org/article/90d229c8fc674b0d8618034c7328de87
Autor:
Xian Zhang, Songyuan Luo, Minjie Wang, Qiongqiong Cao, Zhixin Zhang, Qin Huang, Jie Li, Zhiyong Deng, Tianxiao Liu, Cong-Lin Liu, Mathilde Meppen, Amelie Vromman, Richard A. Flavell, Gökhan S. Hotamışlıgil, Jian Liu, Peter Libby, Zhangsuo Liu, Guo-Ping Shi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Interleukin-18 (IL18) has a pivotal role in interferon signalling and T cell development, but increasingly recognized as an adipokine that regulates energy metabolism in fat tissue. Authors here dissect the function of IL18 signalling in the adipose
Externí odkaz:
https://doaj.org/article/d44ec4db528043358753cc5d4e64f564
Autor:
Yuanyuan Zhang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Shuya Zhang, Minjie Wang, Songyuan Luo, Zhaojie Meng, Jing Liu, Galina K. Sukhova, Dazhu Li, Andrew N. J. McKenzie, Peter Libby, Guo‐Ping Shi, Junli Guo
Publikováno v:
Advanced Science, Vol 10, Iss 7, Pp n/a-n/a (2023)
Abstract Development of abdominal aortic aneurysms (AAA) enhances lesion group‐2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rorafl/flIl7rCre/+ mice or induced ILC2 depletion in Icosfl‐DTR‐fl/+Cd4Cre/+ mice expedi
Externí odkaz:
https://doaj.org/article/5088f16849cc46d4b5b3ce3f82354472
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102133- (2023)
Summary: Mouse hyperglycemia model and islet function assessment are essential in diabetes research. Here, we provide a protocol to evaluate glucose homeostasis and islet functions in diabetic mice and isolated islets. We describe steps for establish
Externí odkaz:
https://doaj.org/article/69a1e5a732454de0a97bfc2a768e1eaa
Autor:
Xiangkun Meng, Zhe Huang, Aiko Inoue, Hailong Wang, Ying Wan, Xueling Yue, Shengnan Xu, Xueying Jin, Guo‐Ping Shi, Masafumi Kuzuya, Xian Wu Cheng
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1197-1209 (2022)
Abstract Background Cachexia is a complicated metabolic disorder that is characterize by progressive atrophy of skeletal muscle. Cathepsin K (CTSK) is a widely expressed cysteine protease that has garnered attention because of its enzymatic and non
Externí odkaz:
https://doaj.org/article/bcf3a8744cce4199ab2e915d1e929490
Autor:
Yuanyuan Zhang, Mingjie Wang, Xian Zhang, Tianxiao Liu, Peter Libby, Guo-Ping Shi, Tianyu Xu, Xiaoxia Fu
Publikováno v:
Cardiology Discovery, Vol 1, Iss 4, Pp 233-258 (2021)
Abstract. COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection likely ranks among the deadliest diseases in human history. As with other coronaviruses, SARS-CoV-2 infection damages not only the lungs but also the
Externí odkaz:
https://doaj.org/article/7924bc34c8fc442f98357eae0f591622
Autor:
Jing Liu, Chongzhe Yang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Jie Li, Qin Huang, Conglin Liu, Yunzhe Wang, Dafeng Yang, Galina K. Sukhova, Jes S. Lindholt, Axel Diederichsen, Lars M. Rasmussen, Dazhu Li, Gail Newton, Francis W. Luscinskas, Lijun Liu, Peter Libby, Jing Wang, Junli Guo, Guo-Ping Shi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Blood eosinophil (EOS) counts may serve as risk factors for human coronary heart diseases. Here the authors show that increased circulating and myocardial EOS after myocardial infarction play a cardioprotective role by reducing cardiomyocyte death, c
Externí odkaz:
https://doaj.org/article/55842ce25e9141999c860602412da2fc
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T cells (Tregs) are a subset of CD4+ T cells with their immunosuppressive activities to block abnormal or excessive immune responses to self and non-autoantigens. Tregs express the transcription factor Foxp3, maintain the immune homeostasi
Externí odkaz:
https://doaj.org/article/edfd1d6839ed43f99d84dbb9df964c59