Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Guo-Chun Zhou"'
Autor:
Jingjing Li, Zhuyun Liu, Xiaoping Wu, Simon Ming-Yuen Lee, Sai-Wang Seto, Jinming Zhang, Guo-Chun Zhou, George Pak-Heng Leung
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116269- (2024)
AGS-30, a new andrographolide derivative, showed significant anticancer and anti-angiogenic characteristics. However, its role in controlling macrophage polarization and tumor immune response is unknown. Thus, the main goals of this study are to inve
Externí odkaz:
https://doaj.org/article/fecc3371e7024c1d83c259e371e20b6e
Discovery of Novel Andrographolide Derivatives as Antiviral Inhibitors against Human Enterovirus A71
Autor:
Jie Kai Tan, Ran Chen, Regina Ching Hua Lee, Feng Li, Kun Dai, Guo-Chun Zhou, Justin Jang Hann Chu
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 115 (2022)
Hand-foot-and-mouth disease (HFMD) caused by human enterovirus A71 (EV-A71) infection has been associated with severe neurological complications. With the lack of an internationally approved antiviral, coupled with a surge in outbreaks globally, EV-A
Externí odkaz:
https://doaj.org/article/29c6a404c27b42f3b7d86da7c2b16572
Autor:
Arpita Dey, Ran Chen, Feng Li, Subhamita Maitra, Jean-Francois Hernandez, Guo-Chun Zhou, Bruno Vincent
Publikováno v:
Molecules, Vol 26, Iss 24, p 7660 (2021)
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic p
Externí odkaz:
https://doaj.org/article/c68621c20a804985b61232ddfe1cd0b5
Autor:
Xin Nie, Shao-Ru Chen, Kun Wang, Yuran Peng, Yi-Tao Wang, Decai Wang, Ying Wang, Guo-Chun Zhou
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Andrographolide derivatives or analogs exhibit potent anti-inflammatory effects in several disease models through NF-κB activity. In this study, we synthesized different andrographolide derivatives and investigated their effects on the toll
Externí odkaz:
https://doaj.org/article/124559caff544f75908efbc0ce914048
Publikováno v:
网络与信息安全学报, Vol 6, Iss 5, Pp 126-138 (2020)
In recent years, cybersecurity threats have increased, and data-driven security intelligence analysis has become a hot research topic in the field of cybersecurity. In particular, the artificial intelligence technology represented by the knowledge gr
Externí odkaz:
https://doaj.org/article/393c18138860492793ca73387899c7cd
Autor:
Guang-Feng Zhou, Weiyi Qian, Feng Li, Ren-Hua Yang, Na Wang, Chang-Bo Zheng, Chun-Yan Li, Xue-Rong Gu, Liu-Meng Yang, Jinsong Liu, Si-Dong Xiong, Guo-Chun Zhou, Yong-Tang Zheng
Publikováno v:
Antiviral Research. 214:105607
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f320f0764ce3cc2dcb4b311e4b7c554
https://doi.org/10.1016/j.antiviral.2023.105607
https://doi.org/10.1016/j.antiviral.2023.105607
Autor:
Guang-Feng Zhou, Feng Li, Jian-Xia Xue, Weiyi Qian, Xue-Rong Gu, Chang-Bo Zheng, Chunyan Li, Liu-Meng Yang, Si-Dong Xiong, Guo-Chun Zhou, Yong-Tang Zheng
Publikováno v:
Virus Research. 326:199062
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c455de89c095e48d8b08f2b92c39c8bf
https://doi.org/10.1016/j.virusres.2023.199062
https://doi.org/10.1016/j.virusres.2023.199062
Autor:
Weiyi Qian, Jian-Xia Xue, Jinxin Xu, Feng Li, Guang-Feng Zhou, Fang Wang, Rong-Hua Luo, Jinsong Liu, Yong-Tang Zheng, Guo-Chun Zhou
Publikováno v:
Bioorganic chemistry. 120
Dengue virus, belonging to a genus Flavivirus, caused public health problem in recent years. One controversial vaccine of DENV was approved and there is no antiviral for the clinic treatment of DENV, therefore, efficient antivirals to DENV are of gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddde7bdd32fc630444a43722e51d37b
https://pubmed.ncbi.nlm.nih.gov/35093691
https://pubmed.ncbi.nlm.nih.gov/35093691
Autor:
Guo-Chun Zhou, Binli Jiang
Publikováno v:
Zeitschrift für Kristallographie-New Crystal Structures, Vol 235, Iss 2, Pp 275-277 (2020)
C19H28N6O7S, monoclinic, P21 (no. 4), a = 8.1573(1) Å, b = 17.4823(1) Å, c = 9.1162(1) Å, β = 116.432(1)°, V = 1164.14(2) Å3, Z = 2, R gt(F) = 0.0273, wR ref(F 2) = 0.0732, T = 170(2) K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12328efa8207b47607e041c60c1fd259
https://doaj.org/article/717d5913a5b94637812932ad95e938bf
https://doaj.org/article/717d5913a5b94637812932ad95e938bf