Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Guo-Chao Chu"'
Autor:
Lu-Jun Liang, Yu Wang, Xiao Hua, Rujing Yuan, Qiong Xia, Rongtian Wang, Chuntong Li, Guo-Chao Chu, Lei Liu, Yi-Ming Li
Publikováno v:
JACS Au, Vol 3, Iss 10, Pp 2873-2882 (2023)
Externí odkaz:
https://doaj.org/article/57bb6ce5668c4a5b829625fe1ec1215b
Publikováno v:
Chemical Communications. 59:1333-1336
A Ub C-terminal acyl azide was synthesized and found to be able to capture DUBs.
Autor:
Zichen Li, Zebin Tong, Qingyue Gong, Huasong Ai, Shuai Peng, Cong Chen, Guo-Chao Chu, Jia-Bin Li
Publikováno v:
Chemical Science. 14:5681-5688
The expedient chemical synthesis of dual-monoubiquitinated histone through the CAET-assisted strategy is presented.
Autor:
Huasong Ai, Guo-Chao Chu, Qingyue Gong, Ze-Bin Tong, Zhiheng Deng, Xin Liu, Fan Yang, Ziyu Xu, Jia-Bin Li, Changlin Tian, Lei Liu
Publikováno v:
Journal of the American Chemical Society. 144(40)
The chemical synthesis of homogeneously modified histones is a powerful approach to quantitatively decipher how post-translational modifications (PTMs) modulate epigenetic events. Herein, we describe the expedient syntheses of a selection of phosphor
Autor:
Lu‐Jun Liang, Guo‐Chao Chu, Qian Qu, Chong Zuo, Junxiong Mao, Qingyun Zheng, Jingnan Chen, Xianbin Meng, Yangwode Jing, Haiteng Deng, Yi‐Ming Li, Lei Liu
Publikováno v:
Angewandte Chemie. 133:17308-17314
Publikováno v:
The Journal of Organic Chemistry. 85:15631-15637
Histone ubiquitination affects the structure and function of nucleosomes. Here, we reported a one-pot synthesis of ubiquitinated histone analogues using 1,3-dibromoacetone (DBA) as the cross-linking reagent. The key step is that under the acidic bora
Autor:
Chong Zuo, Ruichao Ding, Xiangwei Wu, Yuanxia Wang, Guo‐Chao Chu, Lu‐Jun Liang, Huasong Ai, Ze‐Bin Tong, Junxiong Mao, Qingyun Zheng, Tian Wang, Zichen Li, Lei Liu, Demeng Sun
Publikováno v:
Angewandte Chemie (International ed. in English). 61(28)
Sortase A (SrtA)-mediated ligation, a popular method for protein labeling and semi-synthesis, is limited by its reversibility and dependence on the LPxTG motif, where "x" is any amino acid. Here, we report that SrtA can mediate the efficient and irre
Autor:
Jingnan Chen, Wen-Hao Zhang, Tian Wang, Rui Zhao, Linzhi Ye, Haiteng Deng, Qingyun Zheng, Yi-Ming Li, Xiangwei Wu, Guo-Chao Chu, Lei Liu, Jing Shi, Man Pan, Yuanyuan Yu, Chong Zuo, Xin Sui
Publikováno v:
Angewandte Chemie. 132:13598-13603
Autor:
Chong Zuo, Yao Fu, Yi-Ming Li, Chen-Chen Chen, Xiao Hua, Zhongping Zhang, Jing Shi, Xianbin Meng, Guo-Chao Chu
Publikováno v:
Chemistry – A European Journal. 25:16668-16675
The development of powerful and general methods to acquire ubiquitin (Ub) chains has prompted the deciphering of Ub-mediated processes. Herein, the cysteine-aminoethylation assisted chemical ubiquitination (CAACU) strategy is extended and improved to
Publikováno v:
The Journal of Organic Chemistry. 84:14861-14867
Ubiquitin (Ub)-based fluorescent reagents are crucial to explore the activity of deubiquitinases (DUBs). Ub-Rho110-G is one of the preferred tools, whereas the current synthetic route is time-consuming. Here, we report a new semisynthetic strategy to