Zobrazeno 1 - 10
of 1 827
pro vyhledávání: '"Guo Sun"'
Autor:
Bo Xu, Pengfei Song, Feng Jiang, Zhenyuan Cai, Haifeng Gu, Hongmei Gao, Bin Li, Chengbo Liang, Wen Qin, Jingjie Zhang, Jingyan Yan, Daoxin Liu, Guo Sun, Tongzuo Zhang
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Trillions of microbes colonize the ungulate gastrointestinal tract, playing a pivotal role in enhancing host nutrient utilization by breaking down cellulose and hemicellulose present in plants. Here, through large-scale metagenomic assembly,
Externí odkaz:
https://doaj.org/article/732bbbdfba7e42d8b6236f544686756e
Autor:
Xinyun Jian, Cheng Wang, Shijuan Wu, Guo Sun, Chuan Huang, Chengbing Qiu, Yuanzheng Liu, Peter F. Leadlay, Dong Liu, Zixin Deng, Fuling Zhou, Yuhui Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4149-4163 (2024)
Aminoglycosides (AGs) are a class of antibiotics with a broad spectrum of activity. However, their use is limited by safety concerns associated with nephrotoxicity and ototoxicity, as well as drug resistance. To address these issues, semi-synthetic a
Externí odkaz:
https://doaj.org/article/3c9d502866b64bac866eccc70201f248
Publikováno v:
Meitan kexue jishu, Vol 52, Iss 8, Pp 139-145 (2024)
This paper explores the design of safe coal (rock) pillars and the control effect of water pressure on roof water inrush in the “Code for Coal Pillar Retention and Coal Mining in Buildings, Water Bodies, Railways, and Main Tunnels”. Firstly, by a
Externí odkaz:
https://doaj.org/article/a28d67adc9db44bbad12726dd581cf70
Autor:
Jian Wang, Ke Wang, Zhe Deng, Zhiyu Zhong, Guo Sun, Qing Mei, Fuling Zhou, Zixin Deng, Yuhui Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Base editing (BE) faces protospacer adjacent motif (PAM) constraints and off-target effects in both eukaryotes and prokaryotes. For Streptomyces, renowned as one of the most prolific bacterial producers of antibiotics, the challenges are mor
Externí odkaz:
https://doaj.org/article/34f1a8776d9b4f278eeafa2901ac11cb
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e30778- (2024)
Background: Circular RNAs (circRNAs) have significant roles in tumor progression. The role of circRNA derived from ARP2 actin-related protein 2 homolog (circACTR2) has been reported in various human diseases. However, the functions and regulatory mec
Externí odkaz:
https://doaj.org/article/864b7d11cad44bd3b9c11fb6437c919c
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: Silicon is a major trace element in humans and a prospective supporting biomaterial to bone regeneration. Submicron silicon pillars, as a representative surface topography of silicon-based biomaterials, can regulate macrophage and osteo
Externí odkaz:
https://doaj.org/article/9f38cb90a8b24c82bef6acc0434a93c8
Autor:
Guifa Zhai, Yan Zhu, Guo Sun, Fan Zhou, Yangning Sun, Zhou Hong, Chuan Dong, Peter F. Leadlay, Kui Hong, Zixin Deng, Fuling Zhou, Yuhui Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Intermodular recognition in polyketide synthase (PKS) is a key prerequisite for catalysis and assembly-line engineering. Here, the authors present a specific domain interaction between modules and an evolution-oriented strategy for PKS engineering de
Externí odkaz:
https://doaj.org/article/68b0de0c98e240228f465800d7c19b16
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 7, Iss 6, Pp 905-907 (2022)
Pontania dolichura is a leaf-eating pest that mainly damages willow trees and is widely distributed in northern regions. In this study, we sequenced the entire mitochondrial genome of P. dolichura (GenBank accession number: MZ726800). The circular ge
Externí odkaz:
https://doaj.org/article/31613a6dbeae45b68d002f603fa8f027
Autor:
Guo Sun, Chaoqun Hu, Qing Mei, Minghe Luo, Xu Chen, Zhengyuan Li, Yuanzhen Liu, Zixin Deng, Zhengyu Zhang, Yuhui Sun
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Streptovaricin C is an antibiotic containing a methylenedioxy bridge (MDB) moiety essential for its activity. Here, the authors show that a P450 monooxygenase StvP2 catalyses MDB formation, report its crystal structure in complex with the substrate,
Externí odkaz:
https://doaj.org/article/74c1a4c7ed324d9bbb18fb0e408b230a
Autor:
Gen Lu, Kang Ou, Yihan Zhang, Huan Zhang, Shouhua Feng, Zuofeng Yang, Guo Sun, Jinling Liu, Shu Wei, Shude Pan, Zeliang Chen
Publikováno v:
Molecules, Vol 28, Iss 2, p 570 (2023)
The African Swine Fever virus (ASFV) causes an infectious viral disease in pigs of all ages. The development of antiviral drugs primarily aimed at inhibition of proteases required for the proteolysis of viral polyproteins. In this study, the conforma
Externí odkaz:
https://doaj.org/article/bb884ad01f1b44c588adef85feead9dd