Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Guo Du Wu"'
Autor:
Hikaru Fujioka, Peter J. Hunt, Jacek Rozga, Guo-Du Wu, Donald V. Cramer, Achilles A. Demetriou, Albert D. Moscioni
Publikováno v:
Cell Transplantation, Vol 3 (1994)
Renewed interest in the transplantation of isolated hepatocytes into the liver as a potential therapy for liver disease has stimulated the development of methods for the identification of donor cells within the recipient organ. We describe a method f
Externí odkaz:
https://doaj.org/article/89bfca4046fd46089e90d49b2a367a4e
Publikováno v:
Transplantation. 68:15-24
We have previously reported that the early phases of the immune response of rats to hamster xenografts are characterized by the production of IgM xenoantibodies encoded by a restricted group of Ig germline VH genes (VHHAR family). In the later phases
Publikováno v:
Xenotransplantation. 6:90-97
The Forssman antigen has been proposed to be a target for the xenograft reaction in selected species combinations, including the rat and mouse, which are Forssman-negative and -positive species respectively. The mouse represents an important experime
Autor:
Mary Kearns-Jonker, Borie Dc, Haval Shirwan, S. Wakiyama, Eiji Gochi, Guo-Du Wu, Donald V. Cramer
Publikováno v:
Transplantation. 66:1375-1383
Background. The early phases of the host immune response to xenografts are dominated by anti-donor antibodies. The immunological pathways responsible for mediating the host humoral responses to xenografts are largely unknown, and this report addresse
Autor:
Eiji Gochi, Wilson Chu, Donald V. Cramer, Jacques Michel, Mary Kearns-Jonker, Mark Fraiman, Guo-Du Wu
Publikováno v:
Transplantation. 65:1515-1519
Background The rejection of pig xenografts in humans is initiated by preformed antibodies that may be related to the natural antibodies that formulate a first line of defense against infectious agents. Immunoglobulin gene variable domains encoding th
Publikováno v:
Transplantation. 60:1497-1503
The rejection of cardiac xenografts in the hamster-to-rat combination is characterized by the production of IgM antibodies that result in the rapid loss of the graft. We have recently produced rat monoclonal antibodies (mAb) to hamster heart xenograf
Autor:
Guo-Du Wu, Leonard Makowka, Oscar Rodriguez, Haval Shirwan, Borie Dc, Frances A. Chapman, Donald V. Cramer
Publikováno v:
Transplantation. 60:1504-1510
The early phases of the rejection of xenografts exchanged between closely related species are dominated by a vigorous humoral immune response. We have recently used a linker-mediated polymerase chain reaction (LM-PCR) to generate Ig heavy and light c
Autor:
Yvette Middleton, Jacek Rozga, Guo-Du Wu, P. J. Tuso, Donald V. Cramer, Hikaru Fujioka, Albert D. Moscioni, Achilles A. Demetriou, Chikao Yasunaga, Leonard Makowka
Publikováno v:
Liver Transplantation and Surgery. 1:85-93
We have recently conducted a series of experiments to characterize the pattern of reaction of human natural antibodies (NA) with individual pig liver cells. Pooled normal human serum (PHS) was incubated with cultured pig hepatocytes (HEP), aortic end
Publikováno v:
Transplantation. 57:1072-1080
Brequinar sodium (BQR) is a new immunosuppressive drug that is highly effective in preventing graft rejection in several different experimental settings, including primary allografts and xenografts. A short course of BQR treatment during the onset of
Publikováno v:
Transplantation. 55:1375-1378
We have examined the nature of the binding of human xenoantibodies to pig liver and kidney vascular endothelium. Our results demonstrate that human serum contains IgM and IgG xenoantibodies that bind to pig vascular endothelium, and that the pattern