Zobrazeno 1 - 10
of 1 119
pro vyhledávání: '"Guo‐Qiang Chen"'
Autor:
Bing Han, Zhan-Ming Li, Xu-Yun Zhao, Kai Liang, Yu-Qin Mao, Shi-Long Zhang, Li-Ying Huang, Chao-Yue Kong, Xin Peng, Hui-Ling Chen, Jia-Ting Huang, Zhao-Xia Wu, Jin-Qing Yao, Pei-Ran Cai, Zheng-Yan Zhang, Xu-Min Zhang, Zhu-Jun Yao, Guo-Qiang Chen, Li-Shun Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Obesity and related diseases pose a major health risk, yet current anti-obesity drugs inadequately addressing clinical needs. Here we show AA005, an annonaceous acetogenin mimic, resists obesity induced by high-fat diets and leptin mutations
Externí odkaz:
https://doaj.org/article/6fc4b8b8320f4c158db395a138e49514
Autor:
Yudian Zhang, Zihua Li, Xinyi Liu, Xinyu Chen, Shujie Zhang, Yuemeng Chen, Jiangnan Chen, Jin Chen, Fuqing Wu, Guo-Qiang Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract 3-Hydroxybutyrate (3HB) is a small ketone body molecule produced endogenously by the body in the liver. Previous studies have shown that 3HB can reduce blood glucose level in type 2 diabetic (T2D) patients. However, there is no systematic st
Externí odkaz:
https://doaj.org/article/c298d0ed8800485fabee51d5ad0bacd9
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-33 (2023)
Abstract Synthetic biology aims to design or assemble existing bioparts or bio-components for useful bioproperties. During the past decades, progresses have been made to build delicate biocircuits, standardized biological building blocks and to devel
Externí odkaz:
https://doaj.org/article/ff5c257cbd0f4bb3be532b61be430f45
Publikováno v:
Public Health Nutrition, Vol 26, Pp 611-619 (2023)
Abstract Objective: The impact of the dietary potential inflammatory effect on diabetic kidney disease (DKD) has not been adequately investigated. The present study aimed to explore the association between dietary inflammatory index (DII) and DKD in
Externí odkaz:
https://doaj.org/article/6ff59be0954549dc90a020146b4ceb3b
Autor:
Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Background Selectively targeting leukemia stem cells (LSCs) is a promising approach in treating acute myeloid leukemia (AML), for which identification of such therapeutic targets is critical. Increasing lines of evidence indicate that FBXO22
Externí odkaz:
https://doaj.org/article/7412b42ff5bf467e9ec9d00a98e2417e
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 2, Pp 307-321 (2023)
Abstract Halomonas bluephagenesis TD1.0 was engineered to produce the biofuel propane, bioplastic poly‐3‐hydroxybutyrate (PHB), and biochemicals mandelate and hydroxymandelate in a single, semi‐continuous batch fermentation under non‐sterile
Externí odkaz:
https://doaj.org/article/39b4b04f344543ab917b77edbaa9fe02
Publikováno v:
Engineering Biology, Vol 6, Iss 4, Pp 71-81 (2022)
Abstract The bioeconomy drives the development of life science and biotechnology as a blueprint for the future development of human society, and offers a cross‐cutting perspective on the societal transformation towards long‐term sustainability an
Externí odkaz:
https://doaj.org/article/05489fd62d30426c9258105b07339d9f
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundDespite increasing evidence that has shown the association of ultra-processed foods (UPFs) with cancer risk, the results remain inconclusive. We, therefore, conducted the meta-analysis to clarify the association by including recently publis
Externí odkaz:
https://doaj.org/article/059b762620bb4ddd9d33e575e8fef357
Autor:
Matthew Russell, Andrew Currin, William Rowe, Guo-Qiang Chen, Perdita Barran, Nigel S. Scrutton
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-9 (2022)
Measurement(s) Genome • Proteomic Profile Technology Type(s) PacBio Sequel System • nanoflow liquid chromatography-electrospray ionisation mass spectrometry Sample Characteristic - Organism Halomonas sp. TD01
Externí odkaz:
https://doaj.org/article/93575e06332d4a3386ad282de06fbed2
Autor:
Jin Chen, Zihua Li, Yudian Zhang, Xu Zhang, Shujie Zhang, Zonghan Liu, Huimei Yuan, Xiangsheng Pang, Yaxuan Liu, Wuchen Tao, Xiaoping Chen, Peng Zhang, Guo-Qiang Chen
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Background Muscle atrophy is an increasingly global health problem affecting millions, there is a lack of clinical drugs or effective therapy. Excessive loss of muscle mass is the typical characteristic of muscle atrophy, manifesting as musc
Externí odkaz:
https://doaj.org/article/06e875bad60d4813b3de5c4e93084624