Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Guo‐Kai Liu"'
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract Here, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high y
Externí odkaz:
https://doaj.org/article/cfd639dccd07468fbfd091ef3b40b7af
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1552 (2022)
CF2H moiety has a significant potential utility in drug design and discovery, and the incorporation of CF2H into biologically active molecules represents an important and efficient strategy for seeking lead compounds and drug candidates. On the other
Externí odkaz:
https://doaj.org/article/f4b39e4bd6564fe2b53f6c1407b2e32c
Publikováno v:
Organic & Biomolecular Chemistry. 21:4013-4017
A facile and efficient visible-light photoredox-catalyzed protocol for aryldifluoromethylation of N-arylacrylamides was developed and showed good to excellent yields, a broad substrate scope, good tolerance of functional groups, and mild conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba366531d9e0f551d8253cae33df439f
https://doi.org/10.1039/d3ob00488k
https://doi.org/10.1039/d3ob00488k
Publikováno v:
Organic Chemistry Frontiers. 9:2141-2148
The first approach of photoredox catalyzed radical–radical cross-coupling difluoromethylation of C(sp3)−H bond was reported, featuring transition metal-free, good functional group tolerance, broad substrate scope and mild reaction conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06774e499b8f586d3865e28a9ab7590d
https://doi.org/10.1039/d2qo00192f
https://doi.org/10.1039/d2qo00192f
Publikováno v:
Organic Letters. 23:8482-8487
An elegant tandem reaction process for transferring N-allyl amide into CF2H-β-amino alcohol is described. This approach proceeded smoothly under visible light irradiation in the presence of a 3 mol % Ir complex, exhibiting a broad substrate scope an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf0711e33584938b69fa3c0bc34ada55
https://doi.org/10.1021/acs.orglett.1c03242
https://doi.org/10.1021/acs.orglett.1c03242
Publikováno v:
Angewandte Chemie. 134
Monofluoroalkanes are important in many pharmaceuticals, agrochemicals and functional materials. However, the lack of easily available and transformable monofluoroalkylating reagents that facilitate a broad array of transformations has hampered the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62186d7ce7f5ffdc40d56b4bcb8efa47
https://doi.org/10.1002/ange.202208938
https://doi.org/10.1002/ange.202208938
Publikováno v:
European Journal of Organic Chemistry. 2020:5862-5866
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e66561f984ce021b27df6b40fbd68403
https://doi.org/10.1002/ejoc.202000998
https://doi.org/10.1002/ejoc.202000998
Publikováno v:
The Journal of Organic Chemistry. 84:15948-15957
A facile and practical approach for the difluoromethylation of phenols and thiophenols was described. Making use of the recently developed bench-stable S-(difluoromethyl)sulfonium salt as the difluorocarbene precursor, a wide variety of diversely fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072b62f0e8ba607cb758d7c9deaefc2b
https://doi.org/10.1021/acs.joc.9b02424
https://doi.org/10.1021/acs.joc.9b02424
Publikováno v:
Chinese Chemical Letters. 30:1515-1518
A facile and highly efficient approach for selective O-difluoromethylation of 1,3-diones by recently developed bench-stable S-(difluoromethyl)sulfonium salt was described. And a broad range of difluoromthyl enol ethers were readily accessed in good t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13bea89494f60631263324d6d9586998
https://doi.org/10.1016/j.cclet.2019.03.036
https://doi.org/10.1016/j.cclet.2019.03.036
Autor:
Wen-Bing, Qin, Wei, Xiong, Xin, Li, Jia-Yi, Chen, Li-Ting, Lin, Henry N C, Wong, Guo-Kai, Liu
Publikováno v:
The Journal of organic chemistry. 85(16)
A highly efficient approach of visible-light-driven radical difluoromethylation of isocyanides to access a wide variety of difluoromethylated phenanthridines and isoquinolines is herein described. Electrophilic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc5ad874a91774014e8263b9c0645536
https://pubmed.ncbi.nlm.nih.gov/32668153
https://pubmed.ncbi.nlm.nih.gov/32668153