Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Guo, Bao‐Tian"'
Autor:
Runping Zhao, Lei Xu, Jieyun Chen, Yanxian Yang, Xilong Guo, Min Dai, Guo-Bao Tian, Li-Na Qin
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionStaphylococcus aureus is one of the chief pathogens that cause chronic and recurrent infections. Failure of the antibiotics to curb the infections contributes to relapse and is an important reason for the high mortality rate. Treatment fa
Externí odkaz:
https://doaj.org/article/1e92e2197dbc4669bcb036e93d3089ae
Publikováno v:
mLife, Vol 3, Iss 1, Pp 14-20 (2024)
Abstract Clostridioides difficile is a leading cause of healthcare‐associated infections, causing billions of economic losses every year. Its symptoms range from mild diarrhea to life‐threatening damage to the colon. Transmission and recurrence o
Externí odkaz:
https://doaj.org/article/7f53f63db154472b872602f6d7c2c646
Autor:
Li Shao, Changbu Wu, Chengjuan Li, Ruowen He, Guanping Chen, Dandan Sun, Yanxian Yang, Yu Feng, Guili Zhang, Bin Yan, Min Dai, Guo-Bao Tian, Lan-Lan Zhong
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionThe rapid spread of plasmid-mediated tet(X4) conferring high tigecycline resistance poses a significant threat to public health. Escherichia coli as the most common pathogen which carries tet(X4) has been widely disseminated in China. Thu
Externí odkaz:
https://doaj.org/article/7da099fdf9824ca3a0905a039721a1a4
Autor:
Lujie Liang, Lan-Lan Zhong, Lin Wang, Dianrong Zhou, Yaxin Li, Jiachen Li, Yong Chen, Wanfei Liang, Wenjing Wei, Chenchen Zhang, Hui Zhao, Lingxuan Lyu, Nicole Stoesser, Yohei Doi, Fang Bai, Siyuan Feng, Guo-Bao Tian
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002433 (2023)
The emerging and global spread of a novel plasmid-mediated colistin resistance gene, mcr-1, threatens human health. Expression of the MCR-1 protein affects bacterial fitness and this cost correlates with lipid A perturbation. However, the exact molec
Externí odkaz:
https://doaj.org/article/a6365256e8014ed8a66fee907a65a645
Autor:
Chengnan Li, Yingying Gan, Zongshao Li, Mengjing Fu, Yuzhen Li, Xinran Peng, Yongqiang Yang, Guo-bao Tian, Yi Yan Yang, Peiyan Yuan, Xin Ding
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-16 (2023)
Abstract Background P. aeruginosa, a highly virulent Gram-negative bacterium, can cause severe nosocomial infections, and it has developed resistance against most antibiotics. New therapeutic strategies are urgently needed to treat such bacterial inf
Externí odkaz:
https://doaj.org/article/fabd2ad761544100820d2ba66073ec78
Autor:
Siyuan Feng, Wanfei Liang, Jiachen Li, Yong Chen, Dianrong Zhou, Lujie Liang, Daixi Lin, Yaxin Li, Hui Zhao, Huihui Du, Min Dai, Li-Na Qin, Fan Bai, Yohei Doi, Lan-Lan Zhong, Guo-bao Tian
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1236-1249 (2022)
The global dissemination of the mobilized colistin resistance gene, mcr-1, threatens human health. Recent studies by our group and others have shown that the withdrawal of colistin as a feed additive dramatically reduced the prevalence of mcr-1. Alth
Externí odkaz:
https://doaj.org/article/5fb7a8fb55204db2aa092eccaa617b39
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2340-2349 (2022)
Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming, toxin-producing, obligate anaerobic bacterium. C. difficile infection (CDI) is the leading cause of healthcare-associated infective diarrhoea. The infection is mediated by the
Externí odkaz:
https://doaj.org/article/a30fd1d2fe714b809b2f0ef5a48530d5
Autor:
Siyuan Feng, Lujie Liang, Cong Shen, Daixi Lin, Jiachen Li, Lingxuan Lyu, Wanfei Liang, Lan-lan Zhong, Gregory M. Cook, Yohei Doi, Cha Chen, Guo-bao Tian
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 354-367 (2022)
A sharp increase in multidrug-resistant tuberculosis (MDR-TB) threatens human health. Spontaneous mutation in essential gene confers an ability of Mycobacterium tuberculosis resistance to anti-TB drugs. However, conventional laboratory strategies for
Externí odkaz:
https://doaj.org/article/d67b35e00595431bb93212eeaeffbe25
Autor:
Yanxian Yang, Ruowen He, Yiping Wu, Mingyang Qin, Jieyun Chen, Yu Feng, Runping Zhao, Lei Xu, Xilong Guo, Guo-Bao Tian, Min Dai, Bin Yan, Li-Na Qin
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
ObjectivesTigecycline is recognized as one of the last-line antibiotics to treat serious bacterial infection caused by carbapenem-resistant Klebsiella pneumoniae (CRKP). The plasmid-borne gene tet(X4) mediates high resistance to tigecycline. However,
Externí odkaz:
https://doaj.org/article/97ffc7af6f3e43ed94eae1f4741a5569
Autor:
Yanxian Yang, Yongqiang Yang, Mohamed Abd El-Gawad El-Sayed Ahmed, Mingyang Qin, Ruowen He, Yiping Wu, Xiaoxue Liang, Lan-Lan Zhong, Ping Chen, Baoguo Deng, Reem Mostafa Hassan, Weihong Wen, Lingqing Xu, Xubin Huang, Lin Xu, Guo-Bao Tian
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKP) causes serious infections with significant morbidity and mortality. However, the epidemiology and transmission mechanisms of CR-hvKP and the corresponding carbapenem-resis
Externí odkaz:
https://doaj.org/article/0d701688b3414f4e905a21bfb443d0c1