Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Guntur Fibriansah"'
Autor:
Bo Shu, Justin S. G. Ooi, Aaron W. K. Tan, Thiam-Seng Ng, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, Guntur Fibriansah, Jian Shi, Victor A. Kostyuchenko, Gavin R. Screaton, Shee-Mei Lok
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The extracellular secreted NS1 (sNS1) is a major factor contributing to dengue hemorrhagic fever. Here, Shu et al. report sNS1 exists in multiple oligomeric states and presents a tetrameric structure.
Externí odkaz:
https://doaj.org/article/492c441dca1048f8a9bafcc23d53f09b
Autor:
Ter Yong Tan, Guntur Fibriansah, Victor A. Kostyuchenko, Thiam-Seng Ng, Xin-Xiang Lim, Shuijun Zhang, Xin-Ni Lim, Jiaqi Wang, Jian Shi, Marc C. Morais, Davide Corti, Shee-Mei Lok
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus part
Externí odkaz:
https://doaj.org/article/fae32c41b76f496b9784d9e9a446761f
Autor:
Guntur Fibriansah, Elisa X Y Lim, Jan K Marzinek, Thiam-Seng Ng, Joanne L Tan, Roland G Huber, Xin-Ni Lim, Valerie S Y Chew, Victor A Kostyuchenko, Jian Shi, Ganesh S Anand, Peter J Bond, James E Crowe, Shee-Mei Lok
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009331 (2021)
Different strains within a dengue serotype (DENV1-4) can have smooth, or "bumpy" surface morphologies with different antigenic characteristics at average body temperature (37°C). We determined the neutralizing properties of a serotype cross-reactive
Externí odkaz:
https://doaj.org/article/57de8411288847e09ca950df5135c753
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008542 (2020)
Externí odkaz:
https://doaj.org/article/4bb55f0cf76a40d5b7ce10c11c31e4bb
Publikováno v:
Viruses, Vol 13, Iss 8, p 1446 (2021)
The four serotypes of the mature dengue virus can display different morphologies, including the compact spherical, the bumpy spherical and the non-spherical clubshape morphologies. In addition, the maturation process of dengue virus is inefficient an
Externí odkaz:
https://doaj.org/article/0c5ffe0bd12b4aa4a7829b24fc2e7ace
Autor:
Xin-Ni Lim, Chao Shan, Jan K Marzinek, Hongping Dong, Thiam Seng Ng, Justin S G Ooi, Guntur Fibriansah, Jiaqi Wang, Chandra S Verma, Peter J Bond, Pei-Yong Shi, Shee-Mei Lok
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1007996 (2019)
The ability of DENV2 to display different morphologies (hence different antigenic properties) complicates vaccine and therapeutics development. Previous studies showed most strains of laboratory adapted DENV2 particles changed from smooth to "bumpy"
Externí odkaz:
https://doaj.org/article/18a75af2ccfc4cc798a6a0904f00c575
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S9-S9 (2019)
Background: Flaviviruses cause human disease such as dengue fever, West Nile fever, and Zika fever with high degree of severity. There are almost no licensed vaccines and treatment except symptomatic for these diseases. Our group studies the virus st
Externí odkaz:
https://doaj.org/article/ff8f695709a24dfebaa1ccb77eeefac1
Autor:
Guntur Fibriansah, Joanne L Tan, Scott A Smith, Adamberage R de Alwis, Thiam‐Seng Ng, Victor A Kostyuchenko, Kristie D Ibarra, Jiaqi Wang, Eva Harris, Aravinda de Silva, James E Crowe, Shee‐Mei Lok
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 358-371 (2014)
Abstract Dengue virus (DENV), which consists of four serotypes (DENV1‐4), infects over 400 million people annually. Previous studies have indicated most human monoclonal antibodies (HMAbs) from dengue patients are cross‐reactive and poorly neutra
Externí odkaz:
https://doaj.org/article/5a2bbed09b4a44cd9ed0e1bdfbeffee2
Autor:
Guntur Fibriansah, Ákos T Kovács, Trijntje J Pool, Mirjam Boonstra, Oscar P Kuipers, Andy-Mark W H Thunnissen
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48015 (2012)
PadR-like transcriptional regulators form a structurally-related family of proteins that control the expression of genes associated with detoxification, virulence and multi-drug resistance in bacteria. Only a few members of this family have been stud
Externí odkaz:
https://doaj.org/article/38e10a8ea3964b03817f5588f15974c2
Autor:
Michael S. Diamond, Victor A. Kostyuchenko, Arthur S. Kim, Jian Shi, Qun Fei Zhou, Shee-Mei Lok, Julie M. Fox, James T. Earnest, Guntur Fibriansah, Bo Shu, Thiam Seng Ng
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Chikungunya virus (CHIKV) is a significant human pathogen that causes debilitating and long-lasting arthritis. Currently, there is no approved vaccine or specific therapeutic. We show that two highly potent anti-CHIKV antibodies—CHK-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745a4e52e9ffc7190c1e9b128f7af592
https://doi.org/10.1073/pnas.2008051117
https://doi.org/10.1073/pnas.2008051117