Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Gunter P. Eckert"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Aging is the main risk factor for sporadic Alzheimer’s disease (AD), which is characterized by the cerebral deposition of β-amyloid peptides (Aβ) and cognitive decline. Mitochondrial dysfunction is also characteristic of the disease and represent
Externí odkaz:
https://doaj.org/article/83830320b96c496099e1057b85a44880
Autor:
Fabian Schmitt, Gunter P. Eckert
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1550 (2022)
The study of aging is an important topic in contemporary research. Considering the demographic changes and the resulting shifts towards an older population, it is of great interest to preserve youthful physiology in old age. For this endeavor, it is
Externí odkaz:
https://doaj.org/article/cb1bd98461044ba08d9660421003239d
Publikováno v:
Digital Chinese Medicine, Vol 2, Iss 1, Pp 7-18 (2019)
Objective: To confirm evidence regarding the potential therapeutic effect of Hericium erinaceus (H. erinaceus, Hou Tou Gu, 猴头菇) on Alzheimer’s disease (AD) using a system pharmacological approach in silico. Methods: The active compounds of H.
Externí odkaz:
https://doaj.org/article/b8a68ff9d0674657b29098571559a10c
Autor:
Christine Fuchs, Tamara Bakuradze, Regina Steinke, Rekha Grewal, Gunter P. Eckert, Elke Richling
Publikováno v:
Journal of Functional Foods, Vol 70, Iss , Pp 103988- (2020)
Winery by-products arise in high amounts during winemaking processes. Hence, recovery alternatives are of great interest. In this study, effects of extracts from winery by-products (Vitis vinifera L. cv. Riesling) on mitochondrial functions in human
Externí odkaz:
https://doaj.org/article/528d7ce7da2a4d7f88634418c4cb2fc3
Autor:
Maximilian Pohland, Maren Pellowska, Heike Asseburg, Stephanie Hagl, Martina Reutzel, Aljoscha Joppe, Dirk Berressem, Schamim H. Eckert, Mario Wurglics, Manfred Schubert‐Zsilavecz, Gunter P. Eckert
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Current approved drugs for Alzheimer’s disease (AD) only attenuate symptoms, but do not cure the disease. The pirinixic acid derivate MH84 has been characterized as a dual gamma-secretase/proliferator activated receptor gamma (P
Externí odkaz:
https://doaj.org/article/d3adf72618f74d0eb45cc6102776126a
Autor:
Malena Rabenau, Benjamin Dillberger, Madeline Günther, Sylvia Krippner, Veronika Butterweck, Georg Boonen, Jürgen Drewe, Gunter P. Eckert, Carsten Culmsee
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1432 (2021)
Recently, we reported that the Cimicifuga racemosa extract Ze 450 mediated protection from oxidative cell damage through a metabolic shift from oxidative phosphorylation to glycolysis. Here, we investigated the molecular mechanisms underlying the eff
Externí odkaz:
https://doaj.org/article/2f9716fb2e4d4b63b8ffc5f68aa51c8f
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1520 (2021)
Age-related multifactorial diseases, such as the neurodegenerative Alzheimer’s disease (AD), still remain a challenge to today’s society. One mechanism associated with AD and aging in general is mitochondrial dysfunction (MD). Increasing MD is su
Externí odkaz:
https://doaj.org/article/220bd16769a8464cba4e65d65c2bff99
Autor:
Lukas Babylon, Rekha Grewal, Pascal-L. Stahr, Ralph W. Eckert, Cornelia M. Keck, Gunter P. Eckert
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1003 (2021)
Mitochondrial dysfunction represents a hallmark of both brain aging and age-related neurodegenerative disorders including Alzheimer disease (AD). AD-related mitochondrial dysfunction is characterized by an impaired electron transport chain (ETC), sub
Externí odkaz:
https://doaj.org/article/49a4e1f9221243ca96992c843a95020b
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 16524-16539 (2015)
Mitochondria are involved in the aging processes that ultimately lead to neurodegeneration and the development of Alzheimer’s disease (AD). A healthy lifestyle, including a diet rich in antioxidants and polyphenols, represents one strategy to prote
Externí odkaz:
https://doaj.org/article/0dba7aa4c9884b1884995ffd3e097025
Publikováno v:
NFS Journal, Vol 1, Iss C, Pp 3-8 (2015)
Background: Curcuminoids (curcumin, demethoxycurcumin, bis-demethoxycurcumin) are lipophilic polyphenols thought to be effective in the prevention and treatment of neurodegenerative disorders, of which mitochondrial dysfunction is a prominent feature
Externí odkaz:
https://doaj.org/article/a273f65a2aa440d294dc9bd04c8d51a6