Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gunter Klöppel"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 1, Pp 17-23 (2005)
Molecular analyses have demonstrated mutations in the K-ras gene at codon 12 in the majority of pancreatic ductal adenocarcinomas (PDACs). In order to determine whether the K-ras mutation rate increases parallel to the grade of dysplasia in duct lesi
Externí odkaz:
https://doaj.org/article/d9b1f473d7f54c1ba4291293e9ebda49
Autor:
Robert Grützmann, Christian Pilarsky, Ole Ammerpohl, Jutta Luttges, Armin Böhme, Bence Sipos, Melanie Foerder, Ingo Alldinger, Beatrix Jahnke, Hans Konrad Schackert, Holger Kalthoff, Bemd Kremer, Gunter Klöppel, Hans Detlev Saeger
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 5, Pp 611-622 (2004)
Pancreatic ductal adenocarcinoma (PDAC) remains an important cause of malignancy-related death and is the eighth most common cancer with the lowest overall 5-year relative survival rate. To identify new molecular markers and candidates for new therap
Externí odkaz:
https://doaj.org/article/afff49f9d28743e6831b495a3d11d713
Autor:
Anne‐Sophie Litmeyer, Björn Konukiewitz, Atsuko Kasajima, Sebastian Foersch, Felix Schicktanz, Maxime Schmitt, Franziska Kellers, Albert Grass, Paul Jank, Bettina Lehman, Thomas M Gress, Anja Rinke, Detlef K Bartsch, Carsten Denkert, Wilko Weichert, Günter Klöppel, Moritz Jesinghaus
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 6, Pp 498-509 (2023)
Abstract Complementary to synaptophysin and chromogranin A, insulinoma‐associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms. Since there are no comparative data regarding INSM1 expression in c
Externí odkaz:
https://doaj.org/article/341b6cb122f243fc92b1c5ab08d08acc
Autor:
Cornelia Jäkel, Frank Bergmann, Reka Toth, Yassen Assenov, Daniel van der Duin, Oliver Strobel, Thomas Hank, Günter Klöppel, Craig Dorrell, Markus Grompe, Joshua Moss, Yuval Dor, Peter Schirmacher, Christoph Plass, Odilia Popanda, Peter Schmezer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, the authors perform genome- and epigenome-wide analyses from normal and ACC pancreatic tissue that identify aberrations in genome stability and
Externí odkaz:
https://doaj.org/article/d69c18b22f7a4f1a816b05e01db8f13e
Autor:
Emily P. Slater, Konstantin Strauch, Susanne Rospleszcz, Annette Ramaswamy, Irene Esposito, Günter Klöppel, Elvira Matthäi, Kristin Heeger, Volker Fendrich, Peter Langer, Detlef K. Bartsch
Publikováno v:
Translational Oncology, Vol 7, Iss 4, Pp 464-471 (2014)
Screening programs are recommended for individuals at risk (IAR) from families with familial pancreatic cancer (FPC). However, reliable imaging methods or biomarkers for early diagnosis of pancreatic ductal adenocarcinoma (PC) or its precursor lesion
Externí odkaz:
https://doaj.org/article/6670dbf277e345b29b2b06300365b0a9
Autor:
Felix Rückert, Gihan Dawelbait, Christof Winter, Arndt Hartmann, Axel Denz, Ole Ammerpohl, Michael Schroeder, Hans Konrad Schackert, Bence Sipos, Günter Klöppel, Holger Kalthoff, Hans-Detlev Saeger, Christian Pilarsky, Robert Grützmann
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12243 (2010)
BackgroundPancreatic ductal adenocarcinoma (PDAC) remains an important cause of cancer death. Changes in apoptosis signaling in pancreatic cancer result in chemotherapy resistance and aggressive growth and metastasizing. The aim of this study was to
Externí odkaz:
https://doaj.org/article/5de7354ae67846d6b179a55b9bd0ac2a