Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Gunsup Lee"'
Autor:
Sung June Byun, Hoonsung Choi, Shanmugam Sureshkumar, Seong-Su Yuk, Jung-Hoon Kwon, Jin-Yong Noh, Sun Keun Jung, Jeom Sun Kim, Keon Bong Oh, Hyeon Yang, Gunsup Lee, Hwi-Cheul Lee, Jae-Seok Woo, Chang-Seon Song
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-6 (2020)
Abstract Background The 3D8 single chain variable fragment (scFv) is a mini-antibody sequence that exhibits independent nuclease activity against all types of nucleic acids. In this research, crossing a 3D8 scFv G1 transgenic rooster with wild-type h
Externí odkaz:
https://doaj.org/article/5a394dc3dc304fcc980047ddf92e4779
Autor:
Gunsup Lee, Sang Hyoun Park, Haesun Lee, Soo-Jeong Ji, Joo Yung Lee, Sung-June Byun, Seongsoo Hwang, Kyung Woon Kim, Sun A Ock, Keon Bong Oh
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 32, Iss 3, Pp 73-79 (2017)
Transplantation is considered to be a very useful approach to improve human welfare and to prolong life-span. Heterologous organ transplantation using pig organs which are similar to human beings and easy to make mass-production has known as one of t
Externí odkaz:
https://doaj.org/article/83104e26f11c4761acc935ac7610d518
Autor:
Soo-Jeong Ji, Gunsup Lee, Sang Hyoun Park, Kyung Woon Kim, Sung-June Byun, Sun A Ock, Seongsoo Hwang, Jae-Seok Woo, Keon Bong Oh
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 32, Iss 3, Pp 165-170 (2017)
Pigs have been extensively used as mediators of xenotransplantation research. Specifically, the Massachusetts General Hospital (MGH) miniature pig was developed to fix major histocompatibility antigens for use in xenotransplantation studies. We gener
Externí odkaz:
https://doaj.org/article/9ebc38ef794949a98c48bda91ac7850e
Autor:
Sang Hyoun Park, Gunsup Lee, Joo Yung Lee, Kyung Woon Kim, Sung-June Byun, Sun A Ock, Seongsoo Hwang, Hyeon Yang, Jae-Seok Woo, Keon Bong Oh
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 32, Iss 3, Pp 227-233 (2017)
Pig has been known to be one of the most feasible animals as a bioreactor to produce pharmaceuticals in milk and as a mediator in xenotransplantation research. Previously, we generated transgenic pigs for both purposes, which were expressing Factor 8
Externí odkaz:
https://doaj.org/article/476c48c8a270473fba646c887c276d1d
Autor:
Gunsup Lee, Shailesh Budhathoki, Geum-Young Lee, Kwang-ji Oh, Yeon Kyoung Ham, Young-Jun Kim, Ye Rin Lim, Phuong Thi Hoang, Yongjun Lee, Seok-Won Lim, Jun-Mo Kim, Seungchan Cho, Tai-Hyun Kim, Jin-Won Song, Sukchan Lee, Won-Keun Kim
Publikováno v:
Viruses, Vol 13, Iss 4, p 650 (2021)
The virus behind the current pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the etiology of novel coronavirus disease (COVID-19) and poses a critical public health threat worldwide. Effective therapeutics an
Externí odkaz:
https://doaj.org/article/ff73867e4ee245c482f0efdd7020765f
Autor:
Seungchan Cho, Ha-Na Youn, Phuong Mai Hoang, Sungrae Cho, Kee-Eun Kim, Eui-Joon Kil, Gunsup Lee, Mun-Ju Cho, Juhyun Hong, Sung-June Byun, Chang-Seon Song, Sukchan Lee
Publikováno v:
Viruses, Vol 7, Iss 9, Pp 5133-5144 (2015)
The antiviral effect of a catalytic RNA-hydrolyzing antibody, 3D8 scFv, for intranasal administration against avian influenza virus (H1N1) was described. The recombinant 3D8 scFv protein prevented BALB/c mice against H1N1 influenza virus infection by
Externí odkaz:
https://doaj.org/article/05cd8d932b1d436e89c21f1c0334934b
Autor:
Gunsup Lee, Il Sheob Shin, Kang Hee Cho, Se Hee Kim, Juhee Shin, Dae Hyun Kim, Jeong Hee Kim, Hyun Ran Kim
Publikováno v:
Research in Plant Disease, Vol 19, Iss 4, Pp 288-293 (2013)
In worldwide, viral diseases of apple plants has caused the serious problems like reduced production and malformation of fruits. Also, the damages of apple plants by virus and/or viroid infection (Apple chlorotic leaf spot virus, Apple stem groovin
Externí odkaz:
https://doaj.org/article/c91ff30861244f299f39667e24bc7f88
Autor:
Gunsup Lee, Jaelim Yu, Seungchan Cho, Sung-June Byun, Dae Hyun Kim, Taek-Kyun Lee, Myung-Hee Kwon, Sukchan Lee
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004208 (2014)
Viral protein neutralizing antibodies have been developed but they are limited only to the targeted virus and are often susceptible to antigenic drift. Here, we present an alternative strategy for creating virus-resistant cells and animals by ectopic
Externí odkaz:
https://doaj.org/article/565133489b1c46e6a7ae5e80490ac140
Autor:
Jaepyeong Jang, Minh Quan Nguyen, Sangsu Park, Dayoung Ryu, Hyeseon Park, Gunsup Lee, Chong Jai Kim, Yeon Jin Jang, Han Choe
Publikováno v:
Toxicon. 230:107157
Autor:
Gunsup Lee, Jung-Hoon Kwon, Hwi-Cheul Lee, Shanmugam Sureshkumar, Hyeon Yang, Jin-Yong Noh, Seong-Su Yuk, Sung June Byun, Jae-Seok Woo, Sun Keun Jung, Jeom Sun Kim, Chang-Seon Song, Keon Bong Oh, Hoonsung Choi
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-6 (2020)
BMC Veterinary Research
BMC Veterinary Research
Background The 3D8 single chain variable fragment (scFv) is a mini-antibody sequence that exhibits independent nuclease activity against all types of nucleic acids. In this research, crossing a 3D8 scFv G1 transgenic rooster with wild-type hens produ