Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gunsmaa Nyamsuren"'
Autor:
Sandip Kumar Rath, Gunsmaa Nyamsuren, Björn Tampe, David Sung-wen Yu, Melanie S. Hulshoff, Denise Schlösser, Sabine Maamari, Michael Zeisberg, Elisabeth M. Zeisberg
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Cardiac fibrosis is the hallmark of all forms of chronic heart disease. Activation and proliferation of cardiac fibroblasts are the prime mediators of cardiac fibrosis. Existing studies show that ROS and inflammatory cytokines pro
Externí odkaz:
https://doaj.org/article/c9732583a636444882ccab2ad924f6f6
Autor:
Gunsmaa Nyamsuren, Gregor Rapp, Hassan Dihazi, Elisabeth M. Zeisberg, Desiree Tampe, Björn Tampe, Michael Zeisberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Aryl hydrocarbon receptor nuclear translocator (ARNT) mediates anti-fibrotic activity in kidney and liver through induction of ALK3-receptor expression and subsequently increased Smad1/5/8 signaling. While expression of ARNT can be pharmacol
Externí odkaz:
https://doaj.org/article/cf81994b49204e6f825c8f64cf836ecd
Autor:
Maja Životić, Björn Tampe, Gerhard Müller, Claudia Müller, Aleksandar Lipkovski, Xingbo Xu, Gunsmaa Nyamsuren, Michael Zeisberg, Jasmina Marković-Lipkovski
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206786 (2018)
Neural cell adhesion molecule (NCAM) and fibroblast growth factor receptor 1 (FGFR1) cross-talk have been involved in epithelial-to-mesenchymal transition (EMT) process during carcinogenesis. Since EMT also contributes to maladaptive repair and paren
Externí odkaz:
https://doaj.org/article/bbf9f1a22af24a268ab1fea7ac0b0588
Autor:
Gunsmaa Nyamsuren, Aleksandra Kata, Xingbo Xu, Priyadharsini Raju, Ralf Dressel, Wolfgang Engel, D.V. Krishna Pantakani, Ibrahim M. Adham
Publikováno v:
Stem Cell Research, Vol 13, Iss 1, Pp 61-74 (2014)
Pelota (Pelo) is ubiquitously expressed, and its genetic deletion in mice leads to embryonic lethality at an early post-implantation stage. In the present study, we conditionally deleted Pelo and showed that PELO deficiency did not markedly affect th
Externí odkaz:
https://doaj.org/article/e7c2da876a454e9bb52dd51843984aaa
Autor:
Odgerel Oidovsambuu, Gunsmaa Nyamsuren, Shuai Liu, Wolfgang Göring, Wolfgang Engel, Ibrahim M Adham
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25908 (2011)
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three alternatively spliced isoforms o
Externí odkaz:
https://doaj.org/article/138201e3eb0f44e4984937bbc44517dd
Publikováno v:
The FEBS Journal. 288:3317-3329
Differentiation of the embryonic stem cells (ESCs) is regulated by a variety of different signaling pathways. Genetic depletion of murine Pelota gene (Pelo) leads to early embryonic lethality. Here, we aimed at determining the embryonic stage and dec
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Aryl hydrocarbon receptor nuclear translocator (ARNT) mediates anti-fibrotic activity in kidney and liver through induction of ALK3-receptor expression and subsequently increased Smad1/5/8 signaling. While expression of ARNT can b
Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells
Autor:
Björn Tampe, Gunsmaa Nyamsuren, Xingbo Xu, Maja Životić, Müller Ca, Aleksandar Lipkovski, Gerhard A. Müller, Jasmina Markovic-Lipkovski, Michael Zeisberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206786 (2018)
PLoS ONE, Vol 13, Iss 11, p e0206786 (2018)
Neural cell adhesion molecule (NCAM) and fibroblast growth factor receptor 1 (FGFR1) cross-talk have been involved in epithelial-to-mesenchymal transition (EMT) process during carcinogenesis. Since EMT also contributes to maladaptive repair and paren
Autor:
Manar Elkenani, Wolfgang Engel, Erdenechimeg Tsagaan, Priyadharsini Raju, Aleksandra Kata, Ibrahim M. Adham, Gunsmaa Nyamsuren
Publikováno v:
REPRODUCTION. 149:213-221
Pelota (Pelo) is an evolutionarily conserved gene, and its deficiency inDrosophilaaffects both male and female fertility. In mice, genetic ablation ofPeloleads to embryonic lethality at the early implantation stage as a result of the impaired develop
Autor:
Samuel Sossalla, Xiaoying Tan, Raghu Kalluri, Elisabeth M. Zeisberg, Lars S. Maier, Xiaopeng Liu, Xingbo Xu, Gunsmaa Nyamsuren, Gerd Hasenfuss, Björn Tampe, Michael Zeisberg
Publikováno v:
Cardiovascular Research. 105:279-291
Aims Methylation of CpG island promoters is a prototypical epigenetic mechanism to stably control gene expression. The aim of this study was to elucidate the contribution of aberrant promoter DNA methylation in pathological endothelial to mesenchymal