Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gunsagar S Gulati"'
Autor:
Balyn W Zaro, Joseph J Noh, Victoria L Mascetti, Janos Demeter, Benson George, Monika Zukowska, Gunsagar S Gulati, Rahul Sinha, Ryan A Flynn, Allison Banuelos, Allison Zhang, Adam C Wilkinson, Peter Jackson, Irving L Weissman
Publikováno v:
eLife, Vol 9 (2020)
The balance of hematopoietic stem cell (HSC) self-renewal and differentiation is critical for a healthy blood supply; imbalances underlie hematological diseases. The importance of HSCs and their progenitors have led to their extensive characterizatio
Externí odkaz:
https://doaj.org/article/400aec0da9464b239e577082fb119d11
Autor:
Tom W. Andrew, Lauren S. Koepke, Yuting Wang, Michael Lopez, Holly Steininger, Danielle Struck, Tatiana Boyko, Thomas H. Ambrosi, Xinming Tong, Yuxi Sun, Gunsagar S. Gulati, Matthew P. Murphy, Owen Marecic, Ruth Tevlin, Katharina Schallmoser, Dirk Strunk, Jun Seita, Stuart B. Goodman, Fan Yang, Michael T. Longaker, George P. Yang, Charles K. F. Chan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/a776296e94634376a7ce55f548ebe8e1
Autor:
Deshka S. Foster, Clement D. Marshall, Gunsagar S. Gulati, Malini S. Chinta, Alan Nguyen, Ankit Salhotra, R. Ellen Jones, Austin Burcham, Tristan Lerbs, Lu Cui, Megan E. King, Ashley L. Titan, R. Chase Ransom, Anoop Manjunath, Michael S. Hu, Charles P. Blackshear, Shamik Mascharak, Alessandra L. Moore, Jeffrey A. Norton, Cindy J. Kin, Andrew A. Shelton, Michael Januszyk, Geoffrey C. Gurtner, Gerlinde Wernig, Michael T. Longaker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Abdominal adhesions are a common cause of bowel obstruction, but knowledge regarding adhesion biology and anti-adhesion therapies remains limited. Here the authors report a systematic analysis of mouse and human adhesion tissues demonstrating that vi
Externí odkaz:
https://doaj.org/article/737d1dd933494725beaf1af250bea456
Autor:
Shaheen S. Sikandar, Gunsagar S. Gulati, Jane Antony, Isobel Fetter, Angera H. Kuo, William Hai Dang Ho, Veronica Haro-Acosta, Soumyashree Das, Chloé B. Steen, Thiago Almeida Pereira, Dalong Qian, Philip A. Beachy, Fredrick Dirbas, Kristy Red-Horse, Terence H. Rabbitts, Jean Paul Thiery, Aaron M. Newman, Michael F. Clarke
Publikováno v:
Science Advances. 8
Metastasis is responsible for most breast cancer–related deaths; however, identifying the cellular determinants of metastasis has remained challenging. Here, we identified a minority population of immatureTHY1+/VEGFA+tumor epithelial cells in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46f16367ba2549f4caf005b5084bb25c
https://doi.org/10.1126/sciadv.abm3548
https://doi.org/10.1126/sciadv.abm3548
Autor:
Tom W. Andrew, Lauren S. Koepke, Yuting Wang, Michael Lopez, Holly Steininger, Danielle Struck, Tatiana Boyko, Thomas H. Ambrosi, Xinming Tong, Yuxi Sun, Gunsagar S. Gulati, Matthew P. Murphy, Owen Marecic, Ruth Telvin, Katharina Schallmoser, Dirk Strunk, Jun Seita, Stuart B. Goodman, Fan Yang, Michael T. Longaker, George P. Yang, Charles K. F. Chan
Publikováno v:
Nature communications, vol 13, iss 1
Sexually dimorphic tissues are formed by cells that are regulated by sex hormones. While a number of systemic hormones and transcription factors are known to regulate proliferation and differentiation of osteoblasts and osteoclasts, the mechanisms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60ec57ecd3eef2b2c9155edaf837385
https://escholarship.org/uc/item/8sb5f6b9
https://escholarship.org/uc/item/8sb5f6b9
Autor:
Xinming Tong, Matthew P. Murphy, Thomas H. Ambrosi, Norma Neff, Owen Marecic, Malachia Y. Hoover, Fan Yang, Maurizio Morri, Debashis Sahoo, Michael T. Longaker, Yuting Wang, Rachel E. Brewer, Holly Steininger, Lauren S. Koepke, Shamik Mascharak, Eun Young Seo, Irving L. Weissman, Charles Chan, Oyinkansola Ajanaku, Michael Lopez, Gunsagar S. Gulati, Adrian McArdle, Jan Sokol, Jun Seita, Rahul Sinha, Ruth Tevlin, Stephanie D. Conley, Laura Lu
Publikováno v:
Nature, vol 597, iss 7875
Nature
Nature
Loss of skeletal integrity during ageing and disease is associated with an imbalance in the opposing actions of osteoblasts and osteoclasts1. Here we show that intrinsic ageing of skeletal stem cells (SSCs)2 in mice alters signalling in the bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2609fe557a9fd7c0c82562917e6c7dd
https://doi.org/10.1038/s41586-021-03795-7
https://doi.org/10.1038/s41586-021-03795-7
Autor:
Thomas H. Ambrosi, Owen Marecic, Liming Zhao, Benjamin Levi, Marcin P. Walkiewicz, Michael T. Lopez, Yuting Wang, Charles Chan, Ryan C. Ransom, Xinming Tong, Matthew P. Murphy, Holly Steininger, Lauren S. Koepke, Stuart B. Goodman, Gunsagar S. Gulati, Michael T. Longaker, Derrick C. Wan, Malachia Y. Hoover, Natalina Quarto, Irving L. Weissman, Fan Yang
Publikováno v:
Nature Medicine. 26:1583-1592
Osteoarthritis (OA) is a degenerative disease resulting in irreversible, progressive destruction of articular cartilage1. The etiology of OA is complex and involves a variety of factors, including genetic predisposition, acute injury and chronic infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462b5e6694b70e80e988ffc94f47e391
https://doi.org/10.1038/s41591-020-1013-2
https://doi.org/10.1038/s41591-020-1013-2
Autor:
Anoop Manjunath, Geoffrey C. Gurtner, Michael T. Longaker, Ankit Salhotra, Andrew A. Shelton, Charles P. Blackshear, Shamik Mascharak, Lu Cui, Clement D. Marshall, Tristan Lerbs, Cindy Kin, Jeffrey A. Norton, R. Ellen Jones, R. Chase Ransom, Megan E. King, Alessandra L. Moore, Malini Chinta, Gerlinde Wernig, Austin R. Burcham, Gunsagar S. Gulati, Deshka S. Foster, Michael Januszyk, Alan Nguyen, Ashley L. Titan, Michael S. Hu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Adhesions are fibrotic scars that form between abdominal organs following surgery or infection, and may cause bowel obstruction, chronic pain, or infertility. Our understanding of adhesion biology is limited, which explains the paucity of anti-adhesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f54305c5c5d55c0b1fad20125397f2
https://doaj.org/article/737d1dd933494725beaf1af250bea456
https://doaj.org/article/737d1dd933494725beaf1af250bea456
Autor:
Alexander X. Lozano, Aadel A. Chaudhuri, Aishwarya Nene, Antonietta Bacchiocchi, Noah Earland, Matthew D. Vesely, Abul Usmani, Brandon E. Turner, Chloé B. Steen, Bogdan A. Luca, Ti Badri, Gunsagar S. Gulati, Milad R. Vahid, Farnaz Khameneh, Peter K. Harris, David Y. Chen, Kavita Dhodapkar, Mario Sznol, Ruth Halaban, Aaron M. Newman
Publikováno v:
Nat Med
Severe immune-related adverse events (irAEs) occur in up to 60% of patients with melanoma treated with immune checkpoint inhibitors (ICIs). However, it is unknown whether a common baseline immunological state precedes irAE development. Here we applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975031290479ce416099f706a4316045
https://europepmc.org/articles/PMC8866214/
https://europepmc.org/articles/PMC8866214/
Autor:
Oscar Silva, Shamik Mascharak, Heather E. Des Jardins-Park, Kellen Chen, Kathryn E. Yost, Malini Chinta, Clement D. Marshall, Derrick C. Wan, W. Tripp Leavitt, Jeffrey A. Norton, Howard Y. Chang, R. Chase Ransom, Alan T. Nguyen, Geoffrey C. Gurtner, Michael T. Longaker, Dhananjay Wagh, John A. Coller, Ankit Salhotra, Dominic Henn, Gunsagar S. Gulati, Michael Januszyk, Aaron M. Newman, Ashley L. Titan, Austin R. Burcham, R. Ellen Jones, Deshka S. Foster, Karen Tolentino, Michael S. Hu, Gerlinde Wernig
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance In the skin, tissue injury results in fibrosis in the form of a scar composed of dense extracellular matrix deposited by fibroblasts. Therapies that promote tissue regeneration rather than fibrosis remain elusive because principles of fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dc758cbdebf85795b6a9c9ea3a80ee
https://doi.org/10.1073/pnas.2110025118
https://doi.org/10.1073/pnas.2110025118