Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gunnel Engström"'
Autor:
Elizaveta Starodubova, Olga Krotova, David Hallengärd, Yulia Kuzmenko, Gunnel Engström, Diana Legzdina, Oleg Latyshev, Olesja Eliseeva, Anna Karin Maltais, Vera Tunitskaya, Vadim Karpov, Andreas Bråve, Maria Isaguliants
Publikováno v:
Molecular Imaging, Vol 11 (2012)
The efficient cell-mediated immune response clears cells expressing deoxyribonucleic acid (DNA) immunogens, but there are no methods to monitor this in vivo. We hypothesized that immune-mediated clearance can be monitored in vivo if DNA immunogens ar
Externí odkaz:
https://doaj.org/article/897be335bc7842948ed120a1e544abf8
Autor:
Athina Kilpelainen, Gunnel Engström, Stefan Petkov, Alexander V. Ivanov, A. A. Latanova, Britta Wahren, Sergey N. Kochetkov, Olga Krotova, Vadim L. Karpov, Olga A. Smirnova, Maria G. Isaguliants, Elizaveta Starodubova, Yulia Kuzmenko
Publikováno v:
Human Vaccines & Immunotherapeutics. 9:2111-2119
HIV-1 infection induces chronic oxidative stress. The resultant neurotoxicity has been associated with Tat protein. Here, we for the first time describe the induction of oxidative stress by another HIV-1 protein, reverse transcriptase (RT). Expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b18f9ceb4e190eddb05f2a0539e55f0
https://doi.org/10.4161/hv.25813
https://doi.org/10.4161/hv.25813
Autor:
Britta Wahren, Johan Ingvarsson, Carsten Peterson, Morten Krogh, Gunnel Engström, Anders Carlsson, Carl A.K. Borrebaeck, Peter Ellmark, Christer Wingren, Ulrika Harmenberg
Publikováno v:
PROTEOMICS. 8:2211-2219
The driving force behind oncoproteomics is to identify protein signatures that are associated with a particular malignancy. Here, we have used a recombinant scFv antibody microarray in an attempt to classify sera derived from pancreatic adenocarcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc656708bc436502af5951e8e159946e
https://doi.org/10.1002/pmic.200701167
https://doi.org/10.1002/pmic.200701167
Autor:
Richard Stout, M. Ek, Lindvi Gudmundsdotter, Margaret A. Liu, Pontus Blomberg, Andreas Bråve, Kristian Hallermalm, Håkan Mellstedt, Susanne Johansson, Britta Wahren, Gunnel Engström, Andreas Boberg
Publikováno v:
Scandinavian Journal of Immunology. 66:43-51
In preparation for a clinical trial in patients diagnosed with colorectal cancer, a vaccination strategy targeting the carcinoembryonic antigen (CEA) was evaluated in mice using a GMP-produced plasmid DNA vaccine, CEA66, encoding a truncated form of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57cacba91546cf926d19a563a611fac9
https://doi.org/10.1111/j.1365-3083.2007.01945.x
https://doi.org/10.1111/j.1365-3083.2007.01945.x
Autor:
Andreas Boberg, Andreas Bråve, Erik Rollman, Anne Kjerrström, Kajsa Aperia, Reinhold Benthin, Gunnel Engström, Susanne Johansson, Nathalie Louise Mathy, Jorma Hinkula, Jonathan L. Heeney, Cathy van Wely, Peter Franz Ertl, Lars E. Eriksson, Britta Wahren, Gerald Voss
Publikováno v:
Vaccine. 25:2145-2154
A DNA plasmid encoding human immunodeficiency virus type 1 (HIV-1) env, nef and tat genes was used in mice in a prime-boost immunization regimen with the corresponding recombinant proteins. The genetic immunogen was delivered with a gene gun and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c2beb314ae28efe49884a21f239981
https://doi.org/10.1016/j.vaccine.2006.10.057
https://doi.org/10.1016/j.vaccine.2006.10.057
Autor:
Ewa Ljungdahl Ståhle, Staffan Ohlsson, Stefan Schwartz, Gunnel Engström, Michael Levi, Jorma Hinkula, Maria Brytting, Ulla Rudén, Britta Wahren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5f79a16e0b9561f1d6d4479c48e3c8
https://doi.org/10.1159/000425164
https://doi.org/10.1159/000425164
Publikováno v:
Vaccine. 24:4572-4575
C57BL/6 and BALB/c mice were immunized with two different plasmids (p91023B and pKCEA66) encoding different forms of the tumor-associated antigen carcinoembryonic antigen (CEA). The wild type form of CEA (p91023B), which is expressed at the cell surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea437b0db5e55b50d0100db11e7a7aa
https://doi.org/10.1016/j.vaccine.2005.08.044
https://doi.org/10.1016/j.vaccine.2005.08.044
Autor:
Jorma Hinkula, C Svanholm, Maria Brytting, H Glaser, Peter Lundholm, K Okuda, Stefan Schwartz, Birgit Kohleisen, Gunnel Engström, V Erfle, Hans Wigzell, Reinhold Benthin, Britta Wahren, G. Sutter
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Mice immunized with the regulatory genes nef, rev, and tat from human immunodeficiency virus type 1 developed both humoral and cellular immune responses to the gene products Nef, Rev, and Tat. This study demonstrates that it is feasible to induce imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589483fe6f4fc0c857e1328d8866fa64
https://doi.org/10.1128/jvi.71.7.5528-5539.1997
https://doi.org/10.1128/jvi.71.7.5528-5539.1997
Autor:
Elizaveta Starodubova, Olga Krotova, Athina Kilpelainen, Stefan Petkov, Frank Heuts, Gunnel Engström, Maria G. Isaguliants
Publikováno v:
Human vaccinesimmunotherapeutics. 9(10)
The efficacy of DNA vaccines is highly dependent on the methods used for their delivery and the choice of delivery sites/targets for gene injection, pointing at the necessity of a strict control over the gene delivery process. Here, we have investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ce67bdd1acb6d4ef88222e57884096
https://pubmed.ncbi.nlm.nih.gov/23896580
https://pubmed.ncbi.nlm.nih.gov/23896580
Autor:
Volker Erfle, Wolfgang Kastenmüller, Antonio Cosma, Andreas Boberg, Georg Gasteiger, Sven Reiland, Gunnel Engström, Lindvi Gudmundsdotter, Andreas Bråve, Jorma Hinkula, Kristian Hallermalm, Ingo Drexler, Britta Wahren, Erik Rollman
Publikováno v:
Infectious Agents and Cancer, Vol 2, Iss 1, p 14 (2007)
Infect. Agents Cancer 2:14 (2007)
Infectious Agents and Cancer
Infect. Agents Cancer 2:14 (2007)
Infectious Agents and Cancer
Background The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Nef, is an attractive vaccine target because it is involved in viral pathogenesis, is expressed early in the viral life cycle and harbors many T and B cell epitopes. Sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ba75145d7004124437815e24a8726e
https://doi.org/10.1186/1750-9378-2-14
https://doi.org/10.1186/1750-9378-2-14