Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Gunnel Östergren Lundén"'
Autor:
Patrice D. Cani, Gunnel Östergren Lundén, Robert Caesar, Christopher S. Reigstad, Fredrik Bäckhed, Helene Kling Bäckhed, Maria Ketonen, Christoph Reinhardt
Publikováno v:
Gut
BACKGROUND: Obesity is associated with accumulation of macrophages in white adipose tissue (WAT), which contribute to the development of insulin resistance. Germ-free (GF) mice have reduced adiposity and are protected against diet-induced obesity, OB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4046cad544bfb9e523f9377b8f3d6065
Autor:
Gunnel Östergren-Lundén, Göran Bondjers, Pia Stillemark-Billton, Germán Camejo, Annika Asplund
Publikováno v:
Journal of Leukocyte Biology. 86:381-388
Hypoxia-induced modifications of HSPG may be of relevance for the development of atherosclerotic lesions and tumor progression. Macrophages are recruited and retained in hypoxic sites in atherosclerotic lesions and tumors. Furthermore, macrophages ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4c7f3230714bb80615f2e107f0efea
https://doi.org/10.1189/jlb.0908536
https://doi.org/10.1189/jlb.0908536
Autor:
Boel Wallin, Mariam Rodriguez-Lee, Göran Bondjers, Jonatan Moses, Germán Camejo, Gunnel Östergren-Lundén
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:130-135
Objective— The dyslipidemia of insulin resistance, with high levels of albumin-bound fatty acids, is a strong cardiovascular disease risk. Human arterial smooth muscle cell (hASMC) matrix proteoglycans (PGs) contribute to the retention of apoB lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca3cbe2f7a19244de2c5fc933eda660
https://doi.org/10.1161/01.atv.0000191659.94059.62
https://doi.org/10.1161/01.atv.0000191659.94059.62
Autor:
F. Lustig, Pierre Eftekhari, Raquel G Olivas, Gunnel Östergren-Lundén, Gunnar Fager, Alexandra Krettek, Senén Vilaró, Xavier Sanjuan, Johan Hoebeke
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 36:2226-2241
The platelet-derived growth factor (PDGF) family comprises important mitogens for mesenchymal cells. The active dimeric form of PDGF consists of four structurally related A, B, C, and D chains. All PDGF-variants bind to PDGF-receptors. The A and B ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b3e30992bc32509d4b23235c5b6bf5
https://doi.org/10.1016/j.biocel.2004.05.001
https://doi.org/10.1016/j.biocel.2004.05.001
Publikováno v:
Lipids. 39:243-249
Insulin resistance and type 2 diabetes are associated with elevated circulating levels of nonesterified FA (NEFA) and lipoprotein remnants. The dyslipidemia is an important contributor to the excess arterial disease associated with insulin resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad55899ab6ec131115c629f473ea636
https://doi.org/10.1007/s11745-004-1226-2
https://doi.org/10.1007/s11745-004-1226-2
Autor:
Göran Bondjers, Gunnel Östergren Lundén, Mariam Rodríguez Lee, Germán Camejo, Urban Olsson, Malin Lorentzon, Markku Salmivirta, Ann-Charlotte Egnell
Publikováno v:
Diabetes. 50:2126-2132
Insulin resistance and type 2 diabetes are associated with elevated circulating levels of insulin, nonesterified fatty acids (NEFAs), and lipoprotein remnants. Extracellular matrix proteoglycan (PG) alterations are also common in macro- and microvasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901a54111e2be33d9f31482a9537e1d0
https://doi.org/10.2337/diabetes.50.9.2126
https://doi.org/10.2337/diabetes.50.9.2126
Autor:
Carolina Rosmond, G. Bondjers, Gunnel Östergren-Lundén, F. Lustig, Alexandra Krettek, Gunnar Fager
Publikováno v:
Atherosclerosis. 156:267-275
In the early atherosclerotic lesion, monocytes accumulate at sites of inflammation and endothelial injury. Platelet-derived growth factor (PDGF), produced for example by macrophages, is a chemoattractant for smooth muscle cells and possibly also for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff399b66539920d892f6bf526586d78
https://doi.org/10.1016/s0021-9150(00)00644-4
https://doi.org/10.1016/s0021-9150(00)00644-4
Publikováno v:
Glycoconjugate Journal. 18:789-797
Glycosaminoglycans (GAGs) bound to various proteoglycans (PGs) present in the cardiovascular system have been proposed to perform a wide range of functions. These include conferring viscoelastic properties; interacting with and modulating growth fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8f3b61680e7a0460a1818e87b804c46
https://doi.org/10.1023/a:1021155518464
https://doi.org/10.1023/a:1021155518464
Autor:
Ulla Rüetchi, G. Bondjers, Gunnel Östergren-Lundén, Carolina Simonson, Gunnar Fager, Johan Hoebeke, F. Lustig
Publikováno v:
Journal of Molecular Recognition. 12:112-120
The platelet derived growth factor (PDGF), a mitogen for mesenchymal cells, may be bound to and inhibited by heparin and other glycosaminoglycans. PDGF is a homo- or heterodimer of A- and B-chains. They occur as short (A109 and B110) and long (A125 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e868bcbb785231e061e402a911ef02a5
https://doi.org/10.1002/(sici)1099-1352(199903/04)12:2<112::aid-jmr452>3.0.co
https://doi.org/10.1002/(sici)1099-1352(199903/04)12:2<112::aid-jmr452>3.0.co
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:2395-2404
Abstract Platelet-derived growth factor (PDGF) is suggested to play an important role in the development of atherosclerosis as a migratory and mitogenic stimulus to arterial smooth muscle cells (ASMCs). Stimulated and unstimulated ASMCs were studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f2f86b693a500f0b15629552c74500
https://doi.org/10.1161/01.atv.17.11.2395
https://doi.org/10.1161/01.atv.17.11.2395