Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gunnar Weninger"'
Autor:
Marco C. Miotto, Steven Reiken, Anetta Wronska, Qi Yuan, Haikel Dridi, Yang Liu, Gunnar Weninger, Carl Tchagou, Andrew R. Marks
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Heart failure, the leading cause of mortality and morbidity in the developed world, is characterized by cardiac ryanodine receptor 2 channels that are hyperphosphorylated, oxidized, and depleted of the stabilizing subunit calstabin-2. This r
Externí odkaz:
https://doaj.org/article/bc2929b1c98e4fc79d74e5bb8c72f229
Autor:
Gunnar Weninger, Tatiana Pochechueva, Dana El Chami, Xiaojing Luo, Tobias Kohl, Sören Brandenburg, Henning Urlaub, Kaomei Guan, Christof Lenz, Stephan E. Lehnart
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Calpains are calcium-activated neutral proteases involved in the regulation of key signaling pathways. Junctophilin-2 (JP2) is a Calpain-specific proteolytic target and essential structural protein inside Ca2+ release units required for exci
Externí odkaz:
https://doaj.org/article/4776fbc39c47406b95dc5134504a6b9e
Autor:
Haikel Dridi, Gaetano Santulli, Laith Bahlouli, Marco C. Miotto, Gunnar Weninger, Andrew R. Marks
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1409 (2023)
Heart failure is a serious global health challenge, affecting more than 6.2 million people in the United States and is projected to reach over 8 million by 2030. Independent of etiology, failing hearts share common features, including defective calci
Externí odkaz:
https://doaj.org/article/048e4c96f40545ac849ee913a8e67a7a
Autor:
Marco C. Miotto, Gunnar Weninger, Haikel Dridi, Qi Yuan, Yang Liu, Anetta Wronska, Zephan Melville, Leah Sittenfeld, Steven Reiken, Andrew R. Marks
Publikováno v:
Science advances. 8(29)
Ryanodine receptor type 2 (RyR2) mutations have been linked to an inherited form of exercise-induced sudden cardiac death called catecholaminergic polymorphic ventricular tachycardia (CPVT). CPVT results from stress-induced sarcoplasmic reticular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e99fc05077ad8bd07acc4fdbad3d9f
https://pubmed.ncbi.nlm.nih.gov/35857850
https://pubmed.ncbi.nlm.nih.gov/35857850
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bafde0b1c1cb0e2b0007224d604a9ad7
https://doi.org/10.1016/j.yjmcc.2022.08.140
https://doi.org/10.1016/j.yjmcc.2022.08.140
Autor:
Lukas Cyganek, Henning Urlaub, Niels Voigt, Peter Rehling, David Pacheu-Grau, Bernd Wollnik, Gunnar Weninger, Julius Ryan D. Pronto, F. Seibertz, Tobias Kohl, Stephan E. Lehnart, Michael Gotthardt, Eva A. Rog-Zielinska, Daniel Kownatzki-Danger, Henry Sutanto, Jonas Peper, Gerd Hasenfuss, Sören Brandenburg, Robin Hindmarsh, Jordi Heijman, Christof Lenz, Jörg Wegener
Publikováno v:
Circulation Research, 128(6). LIPPINCOTT WILLIAMS & WILKINS
Rationale: CAV3 (caveolin3) variants associated with arrhythmogenic cardiomyopathy and muscular dystrophy can disrupt post-Golgi surface trafficking. As CAV1 (caveolin1) was recently identified in cardiomyocytes, we hypothesize that conserved isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1d8f47fc7526416bb432cb8731c59f
https://doi.org/10.1161/circresaha.119.316547
https://doi.org/10.1161/circresaha.119.316547
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(50)
High-intensity interval training (HIIT) is a time-efficient way of improving physical performance in healthy subjects and in patients with common chronic diseases, but less so in elite endurance athletes. The mechanisms underlying the effectiveness o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b9cf788c8ce1fcd4610517cdea1c52
https://pubmed.ncbi.nlm.nih.gov/26575622
https://pubmed.ncbi.nlm.nih.gov/26575622