Výsledky vyhledávání - "Gunnar O. Brønstad"

Elevated level of β-adrenergic receptors in hepatocytes from regenerating rat liver

Autor: Magne Refsnes, Tor-Erik Sand, Gunnar O. Brønstad, Ivar P. Gladhaug, S. Jacobsen, Dagny Sandnes, Georg Sager, Thoralf Christoffersen

Publikováno v: Experimental Cell Research. 165:117-126

Hepatocytes from regenerating rat liver show an enhanced epinephrine-sensitive adenylate cyclase activity and cAMP response, which may be involved in triggering of the cell proliferation. We have determined adrenergic receptors and adenylate cyclase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ee9340e61956fe7588d2ab62714cefc
https://doi.org/10.1016/0014-4827(86)90537-9

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Changes in hormone responsiveness and cyclic AMP metabolism in rat hepatocytes during primary culture and effects of supplementing the medium with insulin and dexamethasone

Autor: Eva Østby, Tor-Erik Sand, Thoralf Christoffersen, Frode Haffner, Gunnar O. Brønstad, Ole Sonne, Nicholas H. Hunt, Magne Refsnes, Jörgen Huse

Publikováno v: European Journal of Biochemistry. 138:217-226

Primary monolayer cultures of rat hepatocytes were used for studies of long-term and acute effects of hormones on the cyclic AMP system. When hepatocyte lysates were assayed at various times after plating of the cells three major changes in the metab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a979fa24762cb594411b1a5599d689f
https://doi.org/10.1111/j.1432-1033.1984.tb07904.x

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Cyclic AMP metabolism in rat liver during 2-acetylaminofluorene carcinogenesis

Autor: P. Walstad, T. Christofferson, Ivar Øye, Gunnar O. Brønstad

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 372:291-303

Studies on the cyclic AMP metabolism and its control, in rat liver during treatment with carcinogen 2-acetylaminofluorene, prior to tumour development, revealed the following features: 1. 1. Livers from the carcinogen treated rats exhibited greatly e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29c1f755fe14798f027be5f2ca8a2811
https://doi.org/10.1016/0304-4165(74)90192-5

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The proliferative response of rat liver parenchymal cells after partial hepatectomy A methodological study comparing flow cytometry of nuclear DNA content and in vivo and in vitro uptake of thymidine

Autor: Gunnar O. Brønstad, Tor-Erik Sand, V. Digernes, Thoralf Christoffersen

Publikováno v: Cell Proliferation. 15:521-528

DNA synthesis in rat hepatocytes, from livers regenerating after 70% hepatectomy, was assessed by flow cytometric determination of nuclear DNA content and by incorporation of [3H]thymidine. Parenchymal liver cells were isolated by collagenase perfusi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7a0606b14abed1a232ba0bede2cb4f
https://doi.org/10.1111/j.1365-2184.1982.tb01574.x

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Inhibitory effect of prostaglandins on the stimulation by glucagon and adrenaline of formation of cyclic AMP in rat hepatocytes

Autor: Gunnar O. Brønstad, Thoralf Christoffersen

Publikováno v: European journal of biochemistry. 117(2)

Several prostaglandins were found to inhibit hormone-induced cyclic AMP accumulation in suspensions of intact rat hepatocytes. Prostaglandin E1 in concentrations of 0.05--25 micrometers inhibited the cyclic AMP response to glucagon. Maximal inhibitio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54666f248cb551f3ccfc4351bb853fc9
https://pubmed.ncbi.nlm.nih.gov/6268409

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CONTROL OF CYCLIC AMP FORMATION IN CULTURED RAT HEPATOMA CELLS AND IN SOLID RAT HEPATOMAS GROWING IN VIVO

Autor: Gunnar O. Brønstad, Ivar Øye, Thoralf Christoffersen, H.E. Rugstad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94b3e9438a6c1e22237a67506d4ba5a5
https://doi.org/10.1016/b978-0-08-021308-8.50959-5

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Bidirectional concentration-dependent effects of glucagon and dibutyryl cyclic AMP on DNA synthesis in cultured adult rat hepatocytes

Autor: Thoralf Christoffersen, Tor-Erik Sand, Gunnar O. Brønstad

Publikováno v: Biochimica et biophysica acta. 763(1)

Glucagon and dibutyryl cyclic AMP exerted both stimulatory and inhibitory effects on hepatocyte DNA synthesis when added to primary monolayer cultures in the presence of serum, dexamethasone, insulin and epidermal growth factor. The stimulation occur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954d5f98abfb1db8797c6eb827bc044b
https://pubmed.ncbi.nlm.nih.gov/6307392

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Increased effect of adrenaline on cyclic AMP formation and positive beta-adrenergic modulation of DNA-synthesis in regenerating hepatocytes

Autor: Gunnar O. Brønstad, Thoralf Christoffersen

Publikováno v: FEBS letters. 120(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d521b642b26addb0c09e2c6277d087b
https://pubmed.ncbi.nlm.nih.gov/6254807

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Quantitative aspects of the effects of insulin, epidermal growth factor and dexamethasone on DNA synthesis in cultured adult rat hepatocytes

Autor: Magne Refsnes, Vemund Digernes, Gunnar O. Brønstad, Thoralf Christoffersen, Tor-Erik Sand, Wasfiyeh Amara, Anne Killi

Publikováno v: Acta endocrinologica. 109(3)

Epidermal growth factor (EGF) and insulin in combination have previously been shown to initiate S-phase in primary cultures of adult rat hepatocytes. We here describe the detailed time course and dosedependency of the effects of EGF and insulin on DN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d36ed7c2aa6e351990acaaa85171aae
https://pubmed.ncbi.nlm.nih.gov/3895801

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