Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gunnar, Thorsén"'
Autor:
Gunnar Thorsén, Alessandro Quaranta, Federico Marini, Isabella Karlsson, Lorena Ndreu, Martin Ingelsson
Publikováno v:
Analytical Methods. 11:3331-3340
Alteration of glycosylation has been observed in several diseases, such as cancer and neurodegenerative disorders. The study of changes in glycosylation could lead to a better understanding of mechanisms underlying these diseases and to the identific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5be62c25a2de21ad0999bbe290420fa
https://doi.org/10.1039/c9ay00381a
https://doi.org/10.1039/c9ay00381a
Autor:
Hanna Oskarsson, Ann-Kristin Eriksson Wiklund, Gunnar Thorsén, Gabriela Danielsson, Linda Kumblad
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93774 (2014)
This study investigated the uptake and effects of a common human pharmaceutical, propranolol, on the structure and function of a coastal Baltic Sea model community consisting of macroalga (Ceramium tenuicorne), mussels (Mytilus edulis trossulus), amp
Externí odkaz:
https://doaj.org/article/f67f4697c8844e4cb351e0b60619b196
Autor:
Alessandro Quaranta, Isabella Karlsson, Lorena Ndreu, Gunnar Thorsén, Elena Passarini, Leopold L. Ilag, Maya Spasova
Publikováno v:
The Analyst. 145(5)
Glycosylation influences the structure and functionality of glycoproteins, and is regulated by genetic and environmental factors. The types and abundance of glycans on glycoproteins can vary due to diseases such as cancer, inflammation, autoimmune an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3ab41b32da38db575dab89e318d9df
https://pubmed.ncbi.nlm.nih.gov/31913371
https://pubmed.ncbi.nlm.nih.gov/31913371
Publikováno v:
Science of The Total Environment. 806:151271
Over a period of 12 months, the fate of three hormones, 12 antibiotics and 30 pharmaceutically active substances (PhACs) was investigated during open-air storage without and with composting of anaerobically digested and dewatered sewage sludge. The e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f1b688f69e46cec3d01a1f83431ecc
https://doi.org/10.1016/j.scitotenv.2021.151271
https://doi.org/10.1016/j.scitotenv.2021.151271
Publikováno v:
Journal of separation science. 42(3)
In this work, a novel, efficient, and green sorbent, SiO2 @Fe3 O4 has been created and functionalized with 1-butyl-3-methylimidazolium hexafluorophosphate as an ionic liquid. This sorbent was applied for microextraction of four beta blockers, propran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce4fb66566a9761796800f8dbbb61d5
https://pubmed.ncbi.nlm.nih.gov/30449072
https://pubmed.ncbi.nlm.nih.gov/30449072
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 145
A method we previously developed has been applied to the determination of the glycosylation pattern of specific proteins in biological samples. Six proteins (alpha-1-antitrypsin, transferrin, haptoglobin, C1 inhibitor, alpha-1 acid glycoprotein, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a39385ebd450ef6518ea34b71172b9f
https://pubmed.ncbi.nlm.nih.gov/28734272
https://pubmed.ncbi.nlm.nih.gov/28734272
Autor:
Tran Thi Thuy, Gunnar Thorsén
Publikováno v:
Journal of the American Society for Mass Spectrometry. 24:1053-1063
The serum clearance rate of therapeutic antibodies is important as it affects the clinical efficacy, required dose, and dose frequency. The glycosylation of antibodies has in some studies been shown to have an impact on the elimination rates in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399f62281f64e3807ecb809fda31b3e8
https://doi.org/10.1007/s13361-013-0623-z
https://doi.org/10.1007/s13361-013-0623-z
Autor:
Anna, Sroka-Bartnicka, Isabella, Karlsson, Lorena, Ndreu, Alessandro, Quaranta, Matthijs, Pijnappel, Gunnar, Thorsén
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 132
Glycosylation is one of the most common and important post-translational modifications, influencing both the chemical and the biological properties of proteins. Studying the glycosylation of the entire protein population of a sample can be challengin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::071c5048fe5a3f15f5bde1d3d6969999
https://pubmed.ncbi.nlm.nih.gov/27718394
https://pubmed.ncbi.nlm.nih.gov/27718394
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 70:47-52
Optimal glycosylation with respect to the efficacy, serum half-life time, and immunogenic properties is essential in the generation of therapeutic antibodies. The glycosylation pattern can be affected by several different parameters during the manufa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ce37fa261f1ac553b880489f7d1066
https://doi.org/10.1016/j.jpba.2012.05.020
https://doi.org/10.1016/j.jpba.2012.05.020
Publikováno v:
Analytical and Bioanalytical Chemistry
It has been known for a long time that diseases can be associated with changes to the glycosylation of specific proteins. This has been shown for cancer, immunological disorders, and neurodegenerative diseases. The possibility of using the glycosylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29d41fb26d81aa47ceedfd6f6e49cec5
https://pubmed.ncbi.nlm.nih.gov/27137515
https://pubmed.ncbi.nlm.nih.gov/27137515