Zobrazeno 1 - 10
of 383
pro vyhledávání: '"Gunna, Christiansen"'
Autor:
Jonas Ellegaard Nielsen, Bent Honoré, Karsten Vestergård, Raluca Georgiana Maltesen, Gunna Christiansen, Anna Uhd Bøge, Søren Risom Kristensen, Shona Pedersen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging due to the dy
Externí odkaz:
https://doaj.org/article/41fc1d200018460e9fa27e434581d2aa
Autor:
Zahra Najarzadeh, Hossein Mohammad-Beigi, Jannik Nedergaard Pedersen, Gunna Christiansen, Jan Skov Pedersen, Janni Nielsen, Daniel E. Otzen
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100055- (2022)
Functional amyloids (FA) are proteins which are evolutionarily optimized to form highly stable fibrillar structures that strengthen the bacterial biofilm matrix. FA such as CsgA (E. coli) and FapC (Pseudomonas) are secreted to the bacterial surface w
Externí odkaz:
https://doaj.org/article/c917f718ac5c44b9b32e48c7b8b2d3fa
Autor:
Line Friis Bakmann Christensen, Kirstine Friis Jensen, Janni Nielsen, Brian Stougaard Vad, Gunna Christiansen, Daniel Erik Otzen
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 4029-4039 (2019)
Externí odkaz:
https://doaj.org/article/aad158caa5e94ab883868c291073dfd7
Autor:
Shona Pedersen, Anne Flou Kristensen, Ursula Falkmer, Gunna Christiansen, Søren Risom Kristensen
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253613 (2021)
Small cell lung cancer (SCLC) patients have augmented risk of developing venous thromboembolism, but the mechanisms triggering this burden on the coagulation system remain to be understood. Recently, cell-derived microparticles carrying procoagulant
Externí odkaz:
https://doaj.org/article/e5944bdfb83b4c8b9bb3e2e9e0d318e8
Autor:
Tue Bjerg Bennike, Thomas Gelsing Carlsen, Torkell Ellingsen, Ole Kristian Bonderup, Henning Glerup, Martin Bøgsted, Gunna Christiansen, Svend Birkelund, Vibeke Andersen, Allan Stensballe
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 511-516 (2017)
The datasets presented in this article are related to the research articles entitled âNeutrophil Extracellular Traps in Ulcerative Colitis: A Proteome Analysis of Intestinal Biopsiesâ (Bennike et al., 2015 [1]), and âProteome Analysis of Rheumatoi
Externí odkaz:
https://doaj.org/article/a1f513ec70574dfd8ba61fdd7d681ffc
Autor:
Hossein Mohammad-Beigi, Lars Kjaer, Hoda Eskandari, Farhang Aliakbari, Gunna Christiansen, Gianluca Ruvo, Jane L. Ward, Daniel Erik Otzen
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
The ability of proteins to aggregate to form well-organized β-sheet rich amyloid fibrils is increasingly viewed as a general if regrettable property of the polypeptide chain. Aggregation leads to diseases such as amyloidosis and neurodegeneration in
Externí odkaz:
https://doaj.org/article/752a9179f32e442f8706c3796ab6e2c5
Autor:
Femke van Diggelen, Dean Hrle, Mihaela Apetri, Gunna Christiansen, Gerhard Rammes, Armand Tepper, Daniel Erik Otzen
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213663 (2019)
Parkinson's Disease (PD) is a neurodegenerative disease for which there currently is no cure. Aggregation of the pre-synaptic protein α-synuclein (aSN) into oligomers (αSOs) is believed to play a key role in PD pathology, but little is known about
Externí odkaz:
https://doaj.org/article/79493b1090b74cd88741eba920d51436
Autor:
Thøger Nielsen, Søren Risom Kristensen, Henrik Gregersen, Elena Manuela Teodorescu, Gunna Christiansen, Shona Pedersen
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210835 (2019)
Multiple myeloma (MM) patients have increased risk of developing venous thromboembolism, but the underlying mechanisms and the effect on the coagulation system of the disease and the current cancer therapies are not known. It is possible that cancer-
Externí odkaz:
https://doaj.org/article/dd4a043b259b4874a67a335fa0abfe61
Autor:
Cagla Sahin, Eva Christina Østerlund, Nicklas Österlund, Joana Costeira-Paulo, Jannik Nedergaard Pedersen, Gunna Christiansen, Janni Nielsen, Anne Louise Grønnemose, Søren Kirk Amstrup, Manish K. Tiwari, R. Shyama Prasad Rao, Morten Jannik Bjerrum, Leopold L. Ilag, Michael J. Davies, Erik G. Marklund, Jan Skov Pedersen, Michael Landreh, Ian Max Møller, Thomas J. D. Jørgensen, Daniel Erik Otzen
Publikováno v:
Sahin, C, Østerlund, E C, Österlund, N, Costeira-Paulo, J, Pedersen, J N, Christiansen, G, Nielsen, J, Grønnemose, A L, Amstrup, S K, Tiwari, M K, Rao, R S P, Bjerrum, M J, Ilag, L L, Davies, M J, Marklund, E G, Pedersen, J S, Landreh, M, Møller, I M, Jørgensen, T J D & Otzen, D E 2022, ' Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization ', Journal of the American Chemical Society, vol. 144, no. 27, pp. 11949-11954 . https://doi.org/10.1021/jacs.2c03607
Sahin, C, Osterlund, E C, Osterlund, N, Costeira-Paulo, J, Pedersen, J N, Christiansen, G, Nielsen, J, Grønnemose, A L, Amstrup, S K, Tiwari, M K, Rao, R S P, Bjerrum, M J, Ilag, L L, Davies, M J, Marklund, E G, Pedersen, J S, Landreh, M, Moller, I M, Jorgensen, T J D & Otzen, D E 2022, ' Structural Basis for Dityrosine-Mediated Inhibition of alpha-Synuclein Fibrillization ', Journal of the American Chemical Society, vol. 144, no. 27, pp. 11949-11954 . https://doi.org/10.1021/jacs.2c03607
Sahin, C, Osterlund, E C, Osterlund, N, Costeira-Paulo, J, Pedersen, J N, Christiansen, G, Nielsen, J, Grønnemose, A L, Amstrup, S K, Tiwari, M K, Rao, R S P, Bjerrum, M J, Ilag, L L, Davies, M J, Marklund, E G, Pedersen, J S, Landreh, M, Moller, I M, Jorgensen, T J D & Otzen, D E 2022, ' Structural Basis for Dityrosine-Mediated Inhibition of alpha-Synuclein Fibrillization ', Journal of the American Chemical Society, vol. 144, no. 27, pp. 11949-11954 . https://doi.org/10.1021/jacs.2c03607
alpha-Synuclein (alpha-Syn) is an intrinsically disordered protein which self-assembles into highly organized beta-sheet structures that accumulate in plaques in brains of Parkinson's disease patients. Oxidative stress influences alpha-Syn structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a12848347027ec45af73136d3afcb59
https://doi.org/10.1021/jacs.2c03607
https://doi.org/10.1021/jacs.2c03607
Autor:
Robert Vogel, Frank A. W. Coumans, Raluca G. Maltesen, Anita N. Böing, Katherine E. Bonnington, Marike L. Broekman, Murray F. Broom, Edit I. Buzás, Gunna Christiansen, Najat Hajji, Søren R. Kristensen, Meta J. Kuehn, Sigrid M. Lund, Sybren L. N. Maas, Rienk Nieuwland, Xabier Osteikoetxea, Rosalie Schnoor, Benjamin J. Scicluna, Mitch Shambrook, Jeroen de Vrij, Stephen I. Mann, Andrew F. Hill, Shona Pedersen
Publikováno v:
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-13 (2016)
Background: Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on in-depth quantification, measurement and identification of EV sub-populations. Qua
Externí odkaz:
https://doaj.org/article/456e048ddbcd4679b521f6fe03db04e9