The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma.

Autor: Gunn, Ellen J.¹ (AUTHOR), Williams, John T.¹ (AUTHOR), Huynh, Daniel T.² (AUTHOR), Iannotti, Michael J.¹ (AUTHOR), Han, Changho³ (AUTHOR), Barrios, Francis J.⁴ (AUTHOR), Kendall, Stephen⁵ (AUTHOR), Glackin, Carlotta A.⁵ (AUTHOR), Colby, David A.^3,4 (AUTHOR), Kirshner, Julia¹ (AUTHOR) jkirshne@purdue.edu

Publikováno v: Leukemia & Lymphoma. Jun2011, Vol. 52 Issue 6, p1085-1097. 13p. 1 Color Photograph, 1 Diagram, 1 Chart, 5 Graphs.

Maytansinoid immunoconjugate IMGN901 is cytotoxic in a three-dimensional culture model of multiple myeloma

Autor: Nierste, Brittany A, Gunn, Ellen J, Whiteman, Kathleen R, Lutz, Robert J, Kirshner, Julia

Environmental-mediated drug-resistance (EM-DR) presents a major challenge for therapeutic development. Tissue microenvironment in the form of extracellular matrix, soluble factors, and stroma contribute to EM-DR. In multiple myeloma (MM), drug-resist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c2421650e06eb5b47d1cd6fd8d5a55f6
https://europepmc.org/articles/PMC4913235/

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Maytansinoid immunoconjugate IMGN901 is cytotoxic in a three-dimensional culture model of multiple myeloma.

Autor: Nierste BA; Department of Biological Sciences, Purdue University West Lafayette, IN, 47907, USA., Gunn EJ; Department of Biological Sciences, Purdue University West Lafayette, IN, 47907, USA., Whiteman KR; ImmunoGen Inc. Waltham, MA, 02451, USA., Lutz RJ; ImmunoGen Inc. Waltham, MA, 02451, USA., Kirshner J; Department of Biological Sciences, Purdue UniversityWest Lafayette, IN, 47907, USA; Current address: Ixchel ScientificSan Jose, CA.

Publikováno v: American journal of blood research [Am J Blood Res] 2016 May 18; Vol. 6 (1), pp. 6-18. Date of Electronic Publication: 2016 May 18 (Print Publication: 2016).