Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gunjan D. Manocha"'
Autor:
Donald A. Jurivich, Gunjan D. Manocha
Publikováno v:
Journal of Investigative Surgery, Vol 34, Iss 5, Pp 545-546 (2021)
Externí odkaz:
https://doaj.org/article/785738045249449782506996577f398c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Aging is a major risk factor for Alzheimer’s disease (AD). Insulin-like growth factor-1 receptor (IGF-1R) regulates general aging and lifespan. However, the contribution of IGF-1 to age-related AD pathology and progression is highly controversial.
Externí odkaz:
https://doaj.org/article/a2cf52bfa53c4beb90a805488442e286
Autor:
Holly M. Brown-Borg, Jitendra Kumar Tripathi, Gunjan D. Manocha, Bailey Knopf, Donald A. Jurivich, Shar Rakoczy, Rachana Trivedi
Publikováno v:
GeroScience
How the heat shock axis, repair pathways, and proteostasis impact the rate of aging is not fully understood. Recent reports indicate that normal aging leads to a 50% change in several regulatory elements of the heat shock axis. Most notably is the ag
Autor:
Rachana Trivedi, Sharlene G. Rakoczy, Mary Lizakowski, Holly M. Brown-Borg, Donald A. Jurivich, Gunjan D. Manocha
Publikováno v:
J Gerontol A Biol Sci Med Sci
Age-dependent perturbation of the cellular stress response affects proteostasis and other key functions relevant to cellular action and survival. Central to age-related changes in the stress response is loss of heat shock factor 1 (HSF1)–DNA bindin
Autor:
Joshua A. Kulas, Matthew W. Gorr, Kendra L. Puig, Michael P. McDonald, Colin K. Combs, Justine E. Melvin, Jordan V. Hettwer, Vineeta Tanwar, Loren E. Wold, Mona Sohrabi, Gunjan D. Manocha
Publikováno v:
Environmental Pollution. 241:279-288
Environmental exposure to air pollution has been linked to a number of health problems including organ rejection, lung damage and inflammation. While the deleterious effects of air pollution in adult animals are well documented, the long-term consequ
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Aging is a major risk factor for Alzheimer’s disease (AD). Insulin-like growth factor-1 receptor (IGF-1R) regulates general aging and lifespan. However, the contribution of IGF-1 to age-related AD pathology and progression is highly controversial.
Publikováno v:
Current Alzheimer Research
Background: Alzheimer’s disease (AD) is associated with age-associated central nervous system degeneration and dementia. This decline in the function correlates with deposition of Aβ peptide containing plaques and associated reactive gliosis. The
Autor:
Gunjan D. Manocha, Donald A. Jurivich
Publikováno v:
Journal of investigative surgery : the official journal of the Academy of Surgical Research. 34(5)
This edition of JIS reports on the value of harnessing social media for general surgical training and education [1]. The project’s focus on Twitter is pragmatic because survey studies indicate that...
Autor:
Carter Schimke, Meridee Danks, Donald A. Jurivich, Karen Semmens, Dakota Snustad, Mitchell Floura, Gunjan D. Manocha, Casey Morton, Jeremy Holloway, Sclinda L. Janssen, Marsha Waind
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 18, Iss 10082, p 10082 (2021)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health
Senior population health often is underrepresented in curricula for medical and allied health students. Furthermore, entrenched and dense curricular schedules preclude interprofessional teams from clinical experiences related to senior population hea
Autor:
Colin K. Combs, Christopher M. Norris, Kendra L. Puig, Atreyi Ghatak, Susan D. Kraner, Gunjan D. Manocha
Publikováno v:
Journal of Alzheimer's Disease. 58:775-787
Alzheimer's disease (AD) brains are characterized by fibrillar amyloid-β (Aβ) peptide containing plaques and associated reactive microglia. The proinflammatory phenotype of the microglia suggests that they may negatively affect disease course and c