Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Gunilla Källenius"'
Publikováno v:
International Journal of Infectious Diseases, Vol 141, Iss , Pp 106984- (2024)
Sustained control of Mycobacterium tuberculosis infection without evidence of disease is based on a finely tuned balance between pro- and anti-inflammatory responses. Loss of this balance leads to tuberculosis (TB) disease, in which exacerbated myelo
Externí odkaz:
https://doaj.org/article/b920ef7648604c268da1161562f72885
Autor:
Zaynab Mousavian, Elin Folkesson, Gabrielle Fröberg, Fariba Foroogh, Margarida Correia-Neves, Judith Bruchfeld, Gunilla Källenius, Christopher Sundling
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105652- (2022)
Summary: Annually, approximately 10 million people are diagnosed with active tuberculosis (TB), and 1.4 million die of the disease. If left untreated, each person with active TB will infect 10–15 new individuals. The lack of non-sputum-based diagno
Externí odkaz:
https://doaj.org/article/775ff39e1bfe422db491ea91ccaf2826
Autor:
Margarida Correia-Neves, Jérôme Nigou, Zaynab Mousavian, Christopher Sundling, Gunilla Källenius
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Glycolipids constitute a major part of the cell envelope of Mycobacterium tuberculosis (Mtb). They are potent immunomodulatory molecules recognized by several immune receptors like pattern recognition receptors such as TLR2, DC-SIGN and Dectin-2 on a
Externí odkaz:
https://doaj.org/article/806bb409abdc4091a7577e16b6cef190
Autor:
Jason L Cantera, Lorraine M Lillis, Roger B Peck, Emmanuel Moreau, James A Schouten, Paul Davis, Paul K Drain, Alfred Andama, Abraham Pinter, Masanori Kawasaki, Gunilla Källenius, Christopher Sundling, Karen M Dobos, Danara Flores, Delphi Chatterjee, Eileen Murphy, Olivia R Halas, David S Boyle
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274415 (2022)
Lipoarabinomannan (LAM), a component of the Mycobacterium tuberculosis (MTB) cell wall, is detectable in the urine of MTB infected patients with active tuberculosis (TB). LAM-specific antibodies (Igs) have been developed by a variety of traditional a
Externí odkaz:
https://doaj.org/article/7a7b7ad7248146ab8ee1ba5f61096fc2
Autor:
Carolina S. Silva, Christopher Sundling, Elin Folkesson, Gabrielle Fröberg, Claudia Nobrega, João Canto-Gomes, Benedict J. Chambers, Tadepally Lakshmikanth, Petter Brodin, Judith Bruchfeld, Jérôme Nigou, Margarida Correia-Neves, Gunilla Källenius
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Upon infection with Mycobacterium tuberculosis (Mtb) the host immune response might clear the bacteria, control its growth leading to latent tuberculosis (LTB), or fail to control its growth resulting in active TB (ATB). There is however no clear und
Externí odkaz:
https://doaj.org/article/fa96c632e81d4eb29b1785a92977feef
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/3b3f550a5d0143ce92cf99ae32754ff4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Glycolipids of the cell wall of Mycobacterium tuberculosis (Mtb) are important immunomodulators in tuberculosis. In particular, lipoarabinomannan (LAM) has a profound effect on the innate immune response. LAM and its structural variants can be recogn
Externí odkaz:
https://doaj.org/article/163b11f55d254a5aa6b168f2782b96d6
Autor:
Gabrielle Fröberg, Emilie Wahren Borgström, Erja Chryssanthou, Margarida Correia-Neves, Gunilla Källenius, Judith Bruchfeld
Publikováno v:
ERJ Open Research, Vol 5, Iss 2 (2019)
Tuberculosis (TB) elimination programmes need to target preventive treatment to groups with an increased risk of TB activation, such as individuals with a latent tuberculosis infection (LTBI) acquired recently. Current diagnostic tests for LTBI have
Externí odkaz:
https://doaj.org/article/8bd3c4cbe3aa4d0ab80ed0a6fc1313da
Autor:
Margarida Correia-Neves, Gabrielle Fröberg, Liudmyla Korshun, Sofia Viegas, Paula Vaz, Nehaben Ramanlal, Judith Bruchfeld, Beston Hamasur, Patrick Brennan, Gunilla Källenius
Publikováno v:
ERJ Open Research, Vol 5, Iss 1 (2019)
Tuberculosis (TB) is considered the most onerous of infectious diseases according to recent reports from the World Health Organization. Available tests for TB diagnosis present severe limitations, and a reliable point-of-care (POC) diagnostic test do
Externí odkaz:
https://doaj.org/article/39e801129d26489b92d7d5de5be9b1c6
Autor:
Violet N Chihota, Antoinette Niehaus, Elizabeth M Streicher, Xia Wang, Samantha L Sampson, Peter Mason, Gunilla Källenius, Sayoki G Mfinanga, Marnomorney Pillay, Marisa Klopper, Webster Kasongo, Marcel A Behr, Nicolaas C Gey van Pittius, Paul D van Helden, David Couvin, Nalin Rastogi, Robin M Warren
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200632 (2018)
OBJECTIVE:To investigate the distribution of Mycobacterium tuberculosis genotypes across Africa. METHODS:The SITVIT2 global repository and PUBMED were searched for spoligotype and published genotype data respectively, of M. tuberculosis from Africa.
Externí odkaz:
https://doaj.org/article/34c5093264e9418c983b4caa213bfdab