Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gunilla Gidö"'
Publikováno v:
Neurobiology of Disease, Vol 1, Iss 1, Pp 31-41 (1994)
Mechanisms causing gradual recruitment of damaged cells in the penumbra zone around the core of a focal ischaemic lesion may encompass irregularly occurring depolarization waves of the spreading depression (SD) type, each leading to transient loading
Externí odkaz:
https://doaj.org/article/8bd3d23ad6504d40a3bdddccd7b99ce7
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Around 80–95% of the immature dopaminergic neurons die when embryonic ventral mesencephalic tissue is transplanted. Cell death occurs both during the preparation of donor tissue and after graft implantation, but the effect of combining successful n
Externí odkaz:
https://doaj.org/article/bcb7166377bc43d886dda63e0d3f0111
Autor:
David von Schack, Daniel J. Chin, Mattias Rickhag, Liza Soriano, Gunilla Gidö, Tadeusz Wieloch, Roman Urfer, Mirella Gonzalez-Zulueta, Mehrdad Shamloo, Karoly Nikolich
Publikováno v:
European Journal of Neuroscience. 24:2705-2720
Basic helix-loop-helix PAS domain proteins form a growing family of transcription factors. These proteins are involved in the process of adaptation to cellular stresses and environmental factors such as a change in oxygen concentration. We describe t
Autor:
Morten Krogh, Mehrdad Shamloo, Gunilla Gidö, Scott Lohr, Daniel J. Chin, Karoly Nikolich, Tadeusz Wieloch, Eskil Elmér, Hans Bitter, David von Schack, Joseph C. Murray, Mattias Rickhag
Publikováno v:
Journal of Neurochemistry. 96:14-29
In order to identify biological processes relevant for cell death and survival in the brain following stroke, the postischemic brain transcriptome was studied by a large-scale cDNA array analysis of three peri-infarct brain regions at eight time poin
Autor:
Roger F. Castilho, Thorsten Melcher, Mirella Gonzalez-Zulueta, Gregor Tomasevic, Gunilla Gidö, Karoly Nikolich, Gustav Mattiasson, Mehrdad Shamloo, Tadeusz Wieloch, Kavitha Mathi, Saili Yi, Craig H Warden
Publikováno v:
Nature Medicine. 9:1062-1068
Whereas uncoupling protein 1 (UCP-1) is clearly involved in thermogenesis, the role of UCP-2 is less clear. Using hybridization, cloning techniques and cDNA array analysis to identify inducible neuroprotective genes, we found that neuronal survival c
Publikováno v:
Acta Physiologica Scandinavica. 168:277-285
alpha-phenyl-tert-butyl nitrone (PBN) reduces infarct size, improves recovery of brain energy metabolism and delays the secondary increase in extracellular potassium after focal ischaemia, presumably by trapping OH radicals. We investigated the effec
Publikováno v:
Experimental Brain Research. 120:503-509
The present experiments were undertaken to define changes in tissue calcium metabolism in focal and perifocal ("penumbral") tissues following 2 h of transient middle cerebral artery occlusion (MCAO) in rats, induced with an intraluminal filament occl
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 15:78-87
The objective of the study was to explore whether hypoglycemic brain damage is affected by superimposed acidosis. To that end, animals with insulin-induced hypoglycemic coma, defined in terms of a negative DC potential shift, massive release of K+, o
Publikováno v:
Brain Research. 641:295-302
The objective of this study was to explore how alterations in tissue pH during ischemia influence cell calcium uptake, as this is reflected in the extracellular calcium concentration (Ca2+e). Variations in pH were achieved by making animals hypo-, no
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 13:955-961
The present experiments were designed to provide information on brain calcium metabolism during hypoglycemic coma. We specifically wished to evaluate changes in extracellular calcium concentration (Ca2+e) during prolonged hypoglycemic coma and recove