Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gunhild E. Siboska"'
Autor:
Jesper Just, Niels Anton Friis, Tobias Jung, Tilman Grune, Gunhild E. Siboska, Kim Ryun Drasbek, Simon Lykkemark, Peter Kristensen
Publikováno v:
Just, J, Jung, T, Friis, N A, Lykkemark, S, Drasbek, K R, Siboska, G, Grune, T & Kristensen, P 2015, ' Identification of an unstable 4-hydroxynoneal modification on the 20S proteasome subunit α7 by recombinant antibody technology ', Free Radical Biology & Medicine, vol. 89, pp. 786–792 . https://doi.org/10.1016/j.freeradbiomed.2015.10.405
Free radical biology and medicine, 89: 786-792
Free radical biology and medicine, 89: 786-792
Numerous cellular functions rely on an active proteasome allowing degradation of damaged or misfolded proteins. Therefore changes in the proteasomal activity have important physiological consequences. During oxidative stress the production of free ra
Publikováno v:
Plant Growth Regulation. 32:257-265
In this paper we review the data on the structure and properties of N6-furfuryladenine (kinetin, K) accumulated during the last forty years. In 1955, kinetin was isolated from DNA as an artifactual rearrangement product of the autoclaving process. Su
Publikováno v:
Plant Science. 148:37-45
Kinetin (N 6 -furfuryladenine) was the first cytokinin to be isolated almost 45 years ago from DNA as an artifactual rearrangement product of the autoclaving process. Since then its chemical structure and properties have been well described. Most imp
Autor:
Jan Barciszewski, Gunhild E. Siboska, Miroslawa Z. Barciszewska, Brian F.C. Clark, Suresh I. S. Rattan
Publikováno v:
Molecular Biology Reports. 26:231-238
There are over 100 modified bases and their derivatives found in RNA and DNA. For some of them, data concerning their properties, synthesis and roles in cellular metabolism are available, but for others the knowledge of their functions and biosynthet
Autor:
Jan Barciszewski, Bent O. Pedersen, Brian F.C. Clark, Suresh I. S. Rattan, Gunhild E. Siboska
Publikováno v:
FEBS Letters. 414:457-460
Recently, we have reported the presence of kinetin (N6-furfuryladenine) in commercially available DNA, in freshly extracted cellular DNA and in plant cell extracts. We have also found that kinetin has electrochemical properties which can be used for
Autor:
Jens Nyborg, Ole Steen Kristensen, Poul Nissen, Gunhild E. Siboska, Søren Thirup, Ludmila Reshetnikova
Publikováno v:
Aarhus University
Kristensen, O, Reshetnikova, L, Nissen, P, Siboska, G, Thirup, S & Nyborg, J 1996, ' Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin ', F E B S Letters, vol. 399, no. 1-2, pp. 59-62 .
Kristensen, O, Reshetnikova, L, Nissen, P, Siboska, G, Thirup, S & Nyborg, J 1996, ' Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin ', F E B S Letters, vol. 399, no. 1-2, pp. 59-62 .
Udgivelsesdato: 1996-Dec-9 Kirromycin inhibits bacterial protein synthesis by acting on elongation factor Tu (EF-Tu). Complexes of the antibiotic, Phe-tRNA(Phe), the guanosine triphosphate analog GDPNP, and mesophilic (Escherichia coli), as well as t
Publikováno v:
Biochemical and biophysical research communications. 276(3)
We tested the ability of N(6)-furfuryladenine (kinetin) to protect against oxidative and glycoxidative protein damage generated in vitro by sugars and by an iron/ascorbate system. At 50 microM, kinetin was more efficient (82% inhibition) than adenine
Publikováno v:
Barciszewski, J, Mielcarek, M, Stobiecki, M, Siboska, G & Clark, B F C 2000, ' Identification of 6-furfuryladenine (kinetin) in human urine ', Biochem. Biophys. Res. Commun., vol. 279, pp. 69-73 .
In contrast to the current view of kinetin (K, N(6)-furfuryladenine) as an unnatural and synthetic cytokinin, recently it has been identified in plant DNA and plant extract. Here we describe identification of K in human urine using chromatography/mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8e9141c368fb9e67f467ec89692a1b
https://pure.au.dk/portal/da/publications/identification-of-6furfuryladenine-kinetin-in-human-urine(95229b20-8560-11dc-bee9-02004c4f4f50).html
https://pure.au.dk/portal/da/publications/identification-of-6furfuryladenine-kinetin-in-human-urine(95229b20-8560-11dc-bee9-02004c4f4f50).html
Publikováno v:
Olsen, A, Siboska, G, Rattan, S & Clark, B F C 1999, ' N6-furfuryladenine, kinetin, protects against Fenton reaction-mediated oxidative damage to DNA ', Biochem. Biophys. Res. Commun., vol. 265, pp. 499-502 .
Olsen, A, Siboska, G E, Clark, B F & Rattan, S I 1999, ' N(6)-Furfuryladenine, kinetin, protects against Fenton reaction-mediated oxidative damage to DNA ', Biochemical and Biophysical Research Communications, vol. 265, no. 2, pp. 499-502 . https://doi.org/10.1006/bbrc.1999.1669
Aarhus University
Olsen, A, Siboska, G E, Clark, B F & Rattan, S I 1999, ' N(6)-Furfuryladenine, kinetin, protects against Fenton reaction-mediated oxidative damage to DNA ', Biochemical and Biophysical Research Communications, vol. 265, no. 2, pp. 499-502 . https://doi.org/10.1006/bbrc.1999.1669
Aarhus University
Udgivelsesdato: 1999-Nov-19 N(6)-Furfuryladenine (kinetin) has been shown to have anti-ageing effects on several different systems including plants, human cells in culture, and fruitflies. Since most of the experimental data point toward kinetin acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfbc21da00d9114e769d628fbf7d54b
https://pure.au.dk/portal/da/publications/n6furfuryladenine-kinetin-protects-against-fenton-reactionmediated-oxidative-damage-to-dna(37815cb0-8568-11dc-bee9-02004c4f4f50).html
https://pure.au.dk/portal/da/publications/n6furfuryladenine-kinetin-protects-against-fenton-reactionmediated-oxidative-damage-to-dna(37815cb0-8568-11dc-bee9-02004c4f4f50).html
Autor:
Suresh I. S. Rattan, Bent O. Pedersen, Jan Barciszewski, Brian F.C. Clark, Gunhild E. Siboska
Publikováno v:
Aarhus University
Barciszewski, J, Siboska, G, Pedersen, B O, Clark, B F C & Rattan, S 1997, ' Furfural, a precursor of the cytokinin hormone kinetin, and base propenals are formed by hydroxy radical damage of DNA. ', Biochemical and Biophysical Research Communications, vol. 238, pp. 317-319 .
Barciszewski, J, Siboska, G, Pedersen, B O, Clark, B F C & Rattan, S 1997, ' Furfural, a precursor of the cytokinin hormone kinetin, and base propenals are formed by hydroxy radical damage of DNA. ', Biochemical and Biophysical Research Communications, vol. 238, pp. 317-319 .
Recently, we have detected kinetin (N6-furfuryladenine), a well known cytokinin plant hormone, in commercially available DNA, in freshly extracted cellular DNA and in plant cell extracts. We had suggested that the furfuryl moiety of kinetin originate